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A 75 kDa protein was purified to homogeneity from granule extracts of normal human granulocytes using Sephadex G-75 chromatography, Mono-S cation exchange chromatography and chromatofocusing. The protein consisted of one chain with a molecular mass of 75 kDa, as determined by SDS/PAGE. Tryptic peptide analysis by MALDI-TOF (matrix-assisted laser-desorption ionization-time-of-flight) MS and sequenc

We consider a class of generalized harmonic functions in the open unit disc in the complex plane. Our main results concern a canonical series expansion for such functions. Of particular interest is a certain individual generalized harmonic function which suitably normalized plays the role of an associated Poisson kernel.

Enterococcus faecalis can cause infective endocarditis and other complicated infections. We prospectively investigate the incidence of persistent bacteremia with E. faecalis. Of 50 episodes with monomicrobial E. faecalis bacteremia the control blood culture after 48 to 72 hours was positive in 5 episodes (10%) of which 4 had a complicated focal infection.

A series of new cationic dioxidomolybdenum(VI) complexes [MoO2(Ln)]PF6 (2–5) with the tripodal tetradentate pyridyl aminophenolate ligands HL2-HL5 have been synthesized and characterized. Ligands HL2-HL4 carry substituents in the 4-position of the phenolate ring, viz. Cl, Br and NO2, respectively, whereas the ligand HL5, N-(2-hydroxy-3,5-di-tert-butylbenzyl)-N,N-bis(2-pyridylmethyl)amine, is a der

We contribute to the literature on the assessment of innovation systems by relating the amount of inputs available to the system and its performance through the concept of returns to scale (increasing, constant or decreasing). We study to what extent the size or scale of innovation systems relates to their performance, which is estimated through frontier Data Envelopment Analysis-TOPSIS methods, w

Recent theoretical developments in growth models, triggered particularly by unified theories of growth, suggest that the child quantity-quality trade-off is a defining element in our explanation of a transition from Malthusian stagnation to a sustained growth path. This paper presents a model and derive a testable empirical framework to investigate the role of gender in the trade-off between educa

PurposeZinc has been suggested to be protective against breast cancer, but the evidence remains inconclusive. One reason for inconsistent findings in previous studies may be that zinc only influences the risk of developing certain subtypes of breast cancer. Our study is the first study assessing zinc levels in relation to the risk of different breast cancer subgroups, defined by their tumor charac

Artikeln handlar om domstolsprövningens inriktning vid överprövning av förvaltningsbeslut. I artikeln ställs frågan om det finns skäl att i något avseende förändra den form av allsidig prövning som normalt sker inom ramen för förvaltningsbesvärsinstitutet. Frågan ställs mot bakgrund av att allt fler frågor kan prövas i förvaltningsbeslut, dels som en följd av att begreppet överklagbart beslut i vi

Om den moderna gymnasieskolans plats i samhällsomvandlingen vid 1960-talets ingång

High-risk neuroblastoma has a poor prognosis despite intense treatment, demonstrating the need for new therapeutic strategies. Here we evaluated the effects of rigosertib (ON-01910.Na) in preclinical models of high-risk neuroblastoma. Among several hundred cancer cell lines representing 24 tumor types, neuroblastoma was the most sensitive to rigosertib. Treatment of MYCN-amplified neuroblastoma or

Softwood is of interest as a renewable carbon source for production of lactic acid. Softwood hydrolysate contains a high content of mannose. Lactic acid production from mannose by two modified strains, L-lactic acid producing Pediococcus acidilactici TY112 and D-lactic acid producing ZP26, was investigated in the current work. The two strains efficiently converted mannose to L- and D-lactate isome

Recent outlooks suggest a long-term relevance of internal combustion engines for both power generation and transportation. Nonetheless, stringent pollutant reduction requirements combined with new CO2 mandates draws a challenging scenario, requiring intensive research and development activities to develop and optimize combustion modes to fulfill these requirements. Among the recent advancements, t

In the standard Lambda cold dark matter paradigm, pure dark matter simulations predict dwarf galaxies should inhabit dark matter haloes with a centrally diverging density 'cusp'. This is in conflict with observations that typically favour a constant density 'core'. We investigate this 'cusp-core problem' in 'ultra-faint' dwarf galaxies simulated as part of the 'Engineering Dwarfs at Galaxy formati

Mild cognitive impairment (MCI) can be an early manifestation of Alzheimer's disease (AD) pathology, other pathologic entities [e.g., cerebrovascular disease, Lewy body disease, LATE (limbic-predominant age-related TDP-43 encephalopathy)], or mixed pathologies, with concomitant AD- and non-AD pathology being particularly common, albeit difficult to identify, in living MCI patients. The National In

Most of the work in Referent Grammar so far has focused on syntax, but it is clear that the syntactic rales must rely on some kind of lexical information about the form, meaning and category of the words to be used in the rules. As the lexicon cannot include all possible forms, at least not in such languages as Swedish, Russian and Georgian, some kind of moiphological rules are needed. Such rules

Staphylococcal enterotoxins (SE) pose a great threat to human health due to their ability to bypass antigen presentation and activate large amounts of conventional T cells resulting in a cytokine storm potentially leading to toxic shock syndrome. Unconventional T- and NK cells are also activated by SE but the mechanisms remain poorly understood. In this study, the authors aimed to explore the unde