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Early Detection of Forest Bark Beetle Attack Using Time Series Spatial Variability of Spectral Indexes from Sentinel-2

Bark beetle infestations pose a significant threat to forest ecosystems, necessitating timely intervention for effective management and conservation. This study focuses on an 8,100 km2 area in southern Sweden, heavily impacted by a bark beetle outbreak triggered by a severe drought in 2018. Using spectral indices derived from Sentinel-2 data, it explores the potential of a window-based approach fo

Music and reading activities in early childhood associated with improved language development in preterm infants at 2–3 years of age

Introduction: Children born preterm are at increased risk for adverse neurodevelopmental outcomes. Music and reading activities in childhood could ameliorate these difficulties, as they have shown benefits on both neural and behavioral levels. However, only a few studies have assessed these potential benefits in preterm-born children. We investigated whether music and language activities in early

Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy

Cytidine triphosphate synthetase (CTPS) is a key enzyme in nucleic acid and phospholipid biosynthesis and its activity is increased in certain human cancers, making it a promising drug target. The crystal structure of the synthetase domain of human CTPS, which represents the first structure of a CTPS from an eukaryote, has been determined. The structure is homotetrameric and each active site is fo

Plasmodium motility : actin not actin' like actin

Apicomplexan parasites such as Plasmodium and Toxoplasma display actomyosin-dependent motility in the absence of readily detectable actin polymers. Three recent studies indicate that parasite actin polymers, either harvested from parasites or formed from purified recombinant proteins, are exceptionally short ( approximately 100 nm). We propose that parasite motility could be directed by the transi

Rättskraft och bolagsstämmobeslut – En analys av rättskraftens objektiva utsträckning vid en aktieägares talan mot ett bolagsstämmobeslut

Domens rättskraft hindrar att en sak som redan avgjorts får prövas igen. Att rättskraften begränsas till "saken" brukar benämnas som rättskraftens objektiva utsträckning. Vad "saken" är och följaktligen vad som är samma sak som något annat är emellertid inte en enkel fråga att besvara. Trots en rikhaltig praxis från Högsta domstolen som behandlar ämnet och en långvarig diskussiThe legal force of a judgement prohibits the same subject matter from being tried twice. The fact that the legal force of a judgement is limited to the subject matter is referred to as the objective scope of the legal force. How to decide what constitutes the "subject matter" and consequently what is to be considered the same subject matter as something else is a complex question. Despit

Könskaos i Norden? En analys av åldersgränsen för juridiskt könsbyte

Våren 2024 röstades ett omdebatterat lagförslag igenom i den svenska riksdagen. Under juli 2025 ersätts lag (1972:119) om fastställande av könstillhörighet i vissa fall – könstillhörighetslagen – med en ny. Den nya lagen reducerar rådande 18-årsgräns för det juridiska könsbytet; 16-åringar ska ges möjlighet att ta beslut i frågan, med vårdnadshavares medgivande. Under det senaste decenniet har fIn the spring of 2024, a contentious legislative proposal was voted through in the Swedish parliament. In July 2025 the gender recognition act will be replaced. The new law will reduce the age limit for the right to change legal gender from 18 to 16 years of age, with the consent of the guardians of the youth concerned. Over the last decade, several initiatives have been raised with the objective

Platinum-Tin Surface Alloys Studied during O2 Exposure and CO Oxidation Using Grazing Incidence XANES

Platinum-tin catalysts have been used industrially for decades, but their structural evolution under reaction conditions and the causes of their improved activity relative to platinum are still not well understood. In this study, we investigate Sn/Pt(111) and Sn/Pt(223) surface alloys during oxygen exposure and catalytic CO oxidation using grazing incidence X-ray absorption spectroscopy (GI-XAS).

Conformational Selection of a Tryptophan Side Chain Drives the Generalized Increase in Activity of PET Hydrolases through a Ser/Ile Double Mutation

Poly(ethylene terephthalate) (PET) is the most common polyester plastic in the packaging industry and a major source of environmental pollution due to its single use. Several enzymes, termed PET hydrolases, have been found to hydrolyze this polymer at different temperatures, with the enzyme from Ideonella sakaiensis (IsPETase) having optimal catalytic activity at 30-35 °C. Crystal structures of Is

New and Noteworthy Lichen-Forming and Lichenicolous Fungi 14. Xanthoria Pedersenii and X. Wennergrenii - Two New Species from the Xanthoria Calcicola Subclade (Xanthorioideae, Teloschistaceae) Proved by Integrative Approach

Two species new to science, Xanthoria pedersenii and X. wennergrenii in the Xanthoria calcicola complex (Xanthoria, Xanthorioideae, Teloschistaceae), characterized by a complex of morphological, anatomical and molecular characters, are described, illustrated and compared with closely related taxa.

Photoinduced charge transfer renormalization in NiO

Photodoped states in strongly correlated charge-Transfer insulators are characterized by d-d and d-p interactions and the resulting intertwined dynamics of charge excitations and local multiplets. Here, we use femtosecond x-ray absorption spectroscopy in combination with dynamical mean-field theory to disentangle these contributions in NiO. Upon resonant optical excitation across the charge-Transf

Sensory noise as a possible non-pharmacological intervention for children with attention-deficit/hyperactivity disorder

BakgrundAttention-deficit/hyperactivity disorder (ADHD) är en vanlig neuropsykiatrisk diagnossom påverkar ungefär 5% av jordens barn, med en större andel pojkar än flickor.Diagnosen debuterar oftast i barndomen och kännetecknas av svårigheter meduppmärksamhet, hyperaktivitet och impulsivitet. Dessa symtom gör det svårt för barnatt hantera vardagens krav, särskilt i skolmiljöer som ställer höga kraBackgroundChildren diagnosed with attention-deficit/hyperactivity disorder (ADHD) commonlyexhibit academic underachievement. The condition is thought to be linked to adysregulation of the dopamine (DA) and norepinephrine (NE) systems, which arenormalized with pharmacological medication. While pharmacological and non-pharmacological interventions are available, more than 50% abort treatment after o

Unravelling the force-induced dynamics of integrin-based adhesion complexes

A cell’s ability to sense and respond to mechanical cues from its extracellular environment is essential for maintaining the health of itself and its organism. The mechanical cues a cell encounters include physical forces such as shear, tensile, and compressive forces, as well as cues arising from the mechanical properties of the extracellular matrix (ECM), such as stiffness or composition. Throug

Utility of Simultaneous Left Atrial Strain–Volume Relationship During Passive Leg Lift to Identify Elevated Left Ventricular Filling Pressure—A Proof-of-Concept Study

Background: The assessment of left ventricular (LV) filling pressure in heart failure (HF) poses a diagnostic challenge, as HF patients may have normal LV filling pressures at rest but often display elevated LV filling pressures during exercise. Rapid preload increase during passive leg lift (PLL) may unmask HF in such challenging scenarios. We explored the dynamic interplay between simultaneous l

Aspects of insulin secretion and action in Middle Eastern immigrants to Sweden

Background: Middle Eastern (ME) immigrants to Europe have a higher prevalence of type 2 diabetes (T2D) as compared to Europeans. Previous findings from the MEDIM population-based cohort (Impact of ethnicity and migration on diabetes in Malmö) have shown that ME immigrants are more insulin resistant before developing T2D as compared to native Swedes. However, knowledge is still lacking if there are

Topological Superconductivity in Heavily Doped Single-Layer Graphene

The existence of superconductivity (SC) appears to be established in both twisted and nontwisted graphene multilayers. However, whether their building block, single-layer graphene (SLG), can also host SC remains an open question. Earlier theoretical works predicted that SLG could become a chiral d-wave superconductor driven by electronic interactions when doped to its van Hove singularity, but que