Search results

Filter

Filetype

524864 hits

Revisiting the Standard of Proof for Charges of Exceptional Gravity before the International Court of Justice

The International Court of Justice has consistently required a stricter standard of proof for ‘charges of exceptional gravity’. The Bosnia Genocide and Croatia Genocide cases saw the Court require the high standard of ‘fully conclusive’ evidence across all elements of the allegations of genocide. Despite the difficulties associated with obtaining the necessary evidence of the intent of the perpetr

The New CERN Low-energy Facilities for Neutrino Detector Tests

The beamlines at CERN's North and East Areas offer secondary beams in a wide range of momenta between 0.5 GeV/c and 400 GeV/c for fixed-target experiments as well as for test beam campaigns with a flexible configuration and variable beam composition and intensities. Recently, two new facilities for neutrino detectors tests have been established in an extension of the CERN North Area in context of

Multicentre Studies

The first part of the chapter provides an introduction on the implementation of quality-assurance programmes in nuclear medicine (NM) services. It is argued that participation in interlaboratory comparisons has two main benefits. First, on top of existing local quality-assurance programmes, participation can add a level of reassurance on quality. Second, interlaboratory comparisons are prerequisit

Activity Quantification from Planar Images

Planar imaging was for a long time the most-used technique for image-based activity quantification. Owing to its simplicity and speed, the possibility to acquire dynamic image sequences, and to generate whole-body images at a reasonable acquisition time, it is still frequently used in nuclear-medicine imaging. Today, planar imaging is most commonly used for diagnostic examinations with qualitative

A computational study of the reaction mechanism and stereospecificity of dihydropyrimidinase

Dihydropyrimidinase (DHPase) is a key enzyme in the pyrimidine pathway, the catabolic route for synthesis of β-amino acids. It catalyses the reversible conversion of 5,6-dihydrouracil (DHU) or 5,6-dihydrothymine (DHT) to the corresponding N-carbamoyl-β-amino acids. This enzyme has the potential to be used as a tool in the production of β-amino acids. Here, the reaction mechanism and origin of ster

Cardiac q-space trajectory imaging by motion-compensated tensor-valued diffusion encoding in human heart in vivo

Purpose: Tensor-valued diffusion encoding can probe more specific features of tissue microstructure than what is available by conventional diffusion weighting. In this work, we investigate the technical feasibility of tensor-valued diffusion encoding at high b-values with q-space trajectory imaging (QTI) analysis, in the human heart in vivo. Methods: Ten healthy volunteers were scanned on a 3T sca

Ever Smoking is Not Associated with Performed Spirometry while Occupational Exposure and Respiratory Symptoms are

Objective: Despite recommendations, assessment using spirometry or peak expiratory flow is insufficient in the clinical evaluation of suspected obstructive pulmonary disease. The aim was to investigate factors associated with performing spirometry or peak flow expiratory flow assessment. Methods: Randomly selected subjects from the general population aged 50–65 completed a respiratory questionnair

Does a good story prompt visit intention? Evidence from the augmented reality experience at a heritage site in China

The emergence of digital technology has led researchers, businesses, and entrepreneurs to reflect more on the potential value that Augmented Reality (AR) can play in tourism. Although the relationship between authenticity and travel intention has been examined previously, little is known about how authenticity influences tourist travel intention after an AR experience. To fill this research gap, t

Photodissociation of bromine-substituted nitroimidazole radiosensitizers

Heavy elements and some nitroimidazoles both exhibit radiosensitizing properties through different mechanisms. In an effort to see how the overall radiosensitivity might be affected when the two radiosensitizers are combined in the same molecule, we studied the gas-phase photodissociation of two brominated nitroimidazoles and a bromine-free reference sample. Synchrotron radiation was employed to i

Size characterisation of noble-metal nano-crystals formed in sapphire by ion irradiation and subsequent thermal annealing

Metallic nano-particles embedded in transparent dielectrics are very important for new technological applications because of their unique optical properties. These properties depend strongly on the size and shape of the nano-particles. In order to achieve the synthesis of metallic nano-particles it has been used the technique of ion implantation. This is a very common technique because it allows

Size-and shape-dependent nonlinear optical response of au nanoparticles embedded in sapphire

Nonlinear optical response of Au metallic nanoparticles, synthesized and embedded in sapphire by using ion implantation, as a function of their size and shape is studied. The size of the Au NPs was varied by controlling the annealing time of the gold-irradiated sapphire in a reducing atmosphere. Their shape was changed from approximately spherical to prolate by swift heavy-ion irradiation using Si

Functional genomics approaches to dissect causal DNA variations in obesity and type 2 diabetes

GWAS studies have identified hundreds of loci that associate with obesity and type 2 diabetes. However, the functional relevance of the genetic variants, and their impact on disease or traits, is largely unknown. To address those questions, we applied functional genomics approaches to study genetic variants pertinent to obesity and type 2 diabetes-related traits.In paper I, we demonstrate that rs6

Vocational education in Sweden and youth transitions to working life : - challenges and possibilities in the light of a local follow-up study

The basis of this article is a follow-up study of a cohort of pupils in the third largest city of Sweden, Malmö. The pupils finished fourth grade at compulsory school in 2008. We have data about every individual in the cohort as well as corresponding information about their parents. The information concern educational choices, educational accomplishments, employment relations, incomes from work and

Benefits, Challenges and Applications of Ultra-High Field Magnetic Resonance

Human ultra-high field (UHF) MR at 7T and above has been on a rapid rise since the first installations in the 1990s, motivated by the opportunities created by SNR gains and contrast changes. Research efforts were for long focused mainly on technological developments to cope with the challenges posed by UHF. This has brought 7T MR neuroimaging to maturity and into an application dominated realm, fu