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Loss of Cxcr5 alters neuroblast proliferation and migration in the aged brain

Neurogenesis, the production of new neurons from neural stem cells, dramatically decreases during aging concomitantly with increased inflammation both systemically and in the brain. However, the precise role of inflammation and whether local or systemic factors drive the neurogenic decline during aging is poorly understood. Here, we identify CXCR5/5/CXCL13 signaling as a novel regulator of neuroge

Finding Belonging, Finding Agency : Unaccompanied Refugee Minors Converting to Christianity in the Church of Sweden

The arrival 44,617 unaccompanied refugee minors (URM) to Sweden between 2014 and 2016 was met by a large number of civil society volunteers responding to their needs and assisting them in the early stages of their asylum processes, among them the Church of Sweden (CoS). What was not expected was that thousands of these Muslim-background young people would decide to convert to Christianity. Drawing

The road towards autonomous driving – A differentiated view of institutional agency in path transformation

The purpose of the article is to contribute to conceptual and empirical understandings of institutional agency in path transformation. Previous studies of links between institutional change and industrial transformation have focused mainly on the institutionalization of new practices and influence of territorially defined institutional preconditions, leaving a need to disentangle different types o

Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study

OBJECTIVE: The first-appearing β-cell autoantibody has been shown to influence risk of type 1 diabetes (T1D). Here, we assessed the risk of autoantibody spreading to the second-appearing autoantibody and further progression to clinical disease in the Environmental Determinants of Diabetes in the Young study.RESEARCH DESIGN AND METHODS: Eligible children with increased HLA-DR-DQ genetic risk for T1

Conspiracy Beliefs Are Associated with Lower Knowledge and Higher Anxiety Levels Regarding COVID-19 among Students at the University of Jordan

The world has been afflicted heavily by the burden of coronavirus disease 2019 (COVID-19) that overwhelmed health care systems and caused severe economic and educational deficits, in addition to anxiety among the public. The main aim of this study was to evaluate the mutual effects of belief that the pandemic was the result of a conspiracy on knowledge and anxiety levels among students at the Univ

Word length effects on pictorial memory encoding in 5- to 7-year-old children: An eye-tracking study

How speech coding is used for visual material is critical to understanding the link between language and memory development. Using eye-tracking, the present study examined whether the number of syllables of pictured objects’ names, monosyllabic versus multisyllabic, predicts looking time at the stimuli-objects in the context of a memory task, thereby indicating verbal recoding. The children’s (N =

Concentrations and temporal trends in pesticide biomarkers in urine of Swedish adolescents, 2000–2017

Agricultural pesticides are extensively used for weed- and pest control, resulting in residues of these compounds in food. The general population is mainly exposed through dietary intake. Exposure to certain pesticides has been associated with adverse human health outcomes. Our aim was to assess urinary concentrations and temporal trends in the biomarkers of commonly used pesticides. Samples were

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This expert opinion argues that citizens would not benefit from a temporal VAT reduction as a measure to combat the Corona crisis.

Skåda framtiden i ett ännu okänt förflutet

Artikel om tidsuppfattningars betydelse i tider av kriser och katastrofer med science fiction-filmer som "La Jatée" och "De 12 apornas armé" som exempel och coronapandemin som kontext.

Paul and the Construction of Early Christian Identity

E. P. Sanders’ reconstruction of ancient Judaism resulted in an increasing interest in Paul’s relation to Judaism. While scholars before Sanders commonly assumed that Paul converted to Christianity and thus developed a religious identity separate from Judaism, Sanders’ view of Judaism as a religion of grace forced scholars to problematize Paul’s relation to his religious identity. Three major scho

Endovascular aneurysm repair for symptomatic abdominal aortic aneurysms has comparable results to elective repair in the long term

Objective: Endovascular aneurysm repair (EVAR) has been extensively study regarding elective and ruptured abdominal aortic aneurysm (AAA) repair. However, much less is known about EVAR of symptomatic nonruptured AAA, especially concerning the long-term results. The aim of this study was to assess the outcomes of EVAR of symptomatic AAA compared with asymptomatic AAA at a tertiary center using a si

Comparative analysis on the film cooling mechanisms of elliptical and cylindrical holes with 90° compound angle

Purpose: In this study, numerical simulations are performed to compare the adiabatic film cooling effectiveness and reveal the difference of film cooling mechanisms of two models with the same geometries and cross-section areas of film holes’ exits at three typical blowing ratios (M = 0.5, 1 and 1.5). The two models are an elliptical model and a cylindrical model with 90° compound angle, respectiv

Moral choices and responsibilities: : The home-help service at the borderland of care management when older people consider relocation to a residential home

The aim of this article is to reveal how care workers in the home-help services handle the process when older people’s relocation to a residential home is under consideration. Since the care workers are engaged daily in defining care receivers’ needs and yet have no formal influence on care decisions in Sweden, the focus is on how they solve this dilemma. In this inductive study, the theoretical f

Plasma adrenomedullin peptides and precursor levels in pulmonary arterial hypertension disease severity and risk stratification

Adrenomedullin is a potent vasodilatory peptide, linked to pulmonary arterial hypertension pathology. Proximity extension assays were utilized to study plasma biomarkers related to vasoregulation, with focus on adrenomedullin peptides and precursor levels, collectively referred to as ADM. ADM was measured in 48 treatment-naïve pulmonary arterial hypertension patients at diagnosis, and in 31 of the

Gendered dimensions of migration in relation to climate change

It is widely accepted that climate change may be contributing to population movement and has gendered effects. The relationship between climate change as a direct cause of migration continues to give rise to debates concerning vulnerabilities, while at the same time gendered dimensions of vulnerabilities remain limited to binary approaches. There is limited cross-fertilization between disciplines