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Single amino acid substitutions in the selectivity filter render NbXIP1;1α aquaporin water permeable

BACKGROUND: Aquaporins (AQPs) are integral membrane proteins that facilitate transport of water and/or other small neutral solutes across membranes in all forms of life. The X Intrinsic Proteins (XIPs) are the most recently recognized and the least characterized aquaporin subfamily in higher plants. XIP1s have been shown to be impermeable to water but permeable to boric acid, glycerol, hydrogen pe

Drainage mechanisms in porous media : From piston-like invasion to formation of corner flow networks

Water drainage from porous media is a highly dynamic process often marked by rapid piston-like air invasion events at the front and other rapid interfacial reconfigurations. Liquid phase entrapped behind the moving front drains at significantly slower rates often via gravity driven flow through corners and crevices. This distribution of slowly draining residual water phase determines the plant ava

Factors Associated with Motorcyclists’ Speed Behaviour on Malaysian Roads.

This research uses data from observations of 8277 motorcyclists at various types of roads of the road hierarchy in Malaysia in 2015, to investigate the effects of road characteristics, motorcyclists’ riding behaviour, motorcyclists’ and motorcycles’ characteristics on the occurrence of riding with excessive speed. For data collection and analysis, new software, i.e. MECHROM, was developed. The speThis research uses data from observations of 8277 motorcyclists at various types of roads of the road hierarchy in Malaysia in 2015, to investigate the effects of road characteristics, motorcyclists’ riding behaviour, motorcyclists’ and motorcycles’ characteristics on the occurrence of riding with excessive speed. For data collection and analysis, new software, i.e. MECHROM, was developed. The spe

The tyranny of the averages and the indiscriminate use of risk factors in public health : The case of coronary heart disease

Modern medicine is overwhelmed by a plethora of both established risk factors and novel biomarkers for diseases. The majority of this information is expressed by probabilistic measures of association such as the odds ratio (OR) obtained by calculating differences in average "risk" between exposed and unexposed groups. However, recent research demonstrates that even ORs of considerable magnitude ar

Ignoring Ecosystem-Service Cascades Undermines Policy for Multifunctional Agricultural Landscapes

Over and above food, agricultural landscapes provide citizens with crucial public-good ecosystem services, such as biodiversity conservation, cultural values, recreational opportunities, and food security. Because continuing agricultural intensification undermines the ability of landscapes to provide public goods, policies have been implemented to preserve landscape multifunctionality, but with li

Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes : results from the TEDDY study

AIMS: The onset of clinical type 1 diabetes (T1D) is preceded by the occurrence of disease-specific autoantibodies. The level of autoantibody titers is known to be associated with progression time from the first emergence of autoantibodies to the onset of clinical symptoms, but detailed analyses of this complex relationship are lacking. We aimed to fill this gap by applying advanced statistical mo

Open Badges : Acknowledging Soft Skills Acquisition

In 2010 the Mozilla Foundation established the Digital Open Badges concept as a virtual incarnation of physical counterparts such as a paper certificate or a youth organisation merit badge. Digital Open Badges offer embedded, verifiable, metadata containing information such as the issuer and award criteria. Open Badges can be used to reward learning, participation or achievement. They can be store

Into the Film with Music : Measuring Eyeblinks to Explore the Role of Film Music in Emotional Arousal and Narrative Transportation

In this chapter, we explore whether eyeblinks can be used as a measurementof spectators’ narrative transportation into a cinematic narrative. In ourexperiment, we show that spectators’ eyeblinks increase when watchingfilm clips together with what might be called congruent music. Increasedeyeblinks indicate an emotional arousal that motivates attention, whichin turn is a prerequisite for narrative