Background: In recent years a variety of eHealth solutions has been introduced to enhance efficiency and to empower patients, leading to a more accessible and equitable health care system. Within pediatric care eHealth has been advocated to reduce emergency and hospital outpatient visits, with many parents preferring eHealth to physical visits following the transition from hospital to home. Still,

The ‘Race to Zero’ emissions is here, where cities around the world have recognised the need to reduce greenhouse gas emissions and increase resilience to the impacts of climate change. In this episode, we focus on cities within the USA, and the ‘Race to Zero’ as well as the ‘Race to Resilience’. We interview Angie Fyfe, the Executive Director of ICLEI USA. She provides insights into how cities in

Work rate has a direct impact on the systolic blood pressure (SBP) during aerobic exercise, which may be challenging in the evaluation of the SBP response in athletes reaching high work rates. We aimed to investigate the exercise SBP response in endurance athletes in relation to oxygen uptake (VO2), work rate and to recent reference equations for exercise SBP in the general population. Endurance a

It’s time for Africa. A continent that is home to 1.2 billion people. But how are cities and communities responding to a changing climate and building resilience? In this episode, we discuss how cities in Africa are working with nature and biodiversity. We interview Ingrid Coetzee who is the Director of Biodiversity, Nature and Health at ICLEI Africa and the ICLEI Cities Biodiversity Center. She t

The Taj Mahal, Bollywood, and a cricket powerhouse. India means many things to many people. It is also a country of some 1.3 billion people where mitigation and adaptation to climate change is rising up the agenda. In this episode, we discuss transformative urban action in the City of Pune in India. We interview Kunal Kumar who is Municipal Commissioner from the Pune Municipal Corporation in India

Medals at the Olympics, the Oscars in Hollywood, Nobel Prizes for scientists – but what about an award for cities working with sustainability? In this episode, we discuss the ‘Prize for Cities’ recognising transformative projects in cities around the world that are igniting innovation on sustainability and climate action. We interview Rogier Vandenberg – the Global Director for the Ross Centre for

Therapeutic resistance is one of the main reasons for treatment failure in cancer patients. The polyaneuploid cancer cell (PACC) state has been shown to promote resistance by providing a refuge for cancer cells from the effects of therapy and by helping them adapt to a variety of environmental stressors. This state is the result of aneuploid cancer cells undergoing whole genome doubling and skippi

Purpose: Allogeneic hematopoietic stem cell transplantation (HSCT) is an intensive curative treatment that increases family caregivers’ burden. The aim of this study was to explore the feasibility of remotely assessing and addressing family caregivers’ support needs in terms of demand and acceptability using the Carer Support Needs Assessment Tool Intervention (CSNAT-I) in the HSCT context. Method

Droughts affect ecosystems at multiple time scales, but their sub-seasonal legacy effects on vegetation activity remain unclear. Combining the satellite-based enhanced vegetation index MODIS EVI with a novel location-specific definition of the growing season, we quantify drought impacts on sub-seasonal vegetation activity and the subsequent recovery in the Northern Hemisphere. Drought legacy effec

Heat exchanger network synthesis is an essential optimisation tool for Process Integration, particularly in energy-intensive industries. Proper design or retrofit of heat exchanger network can enable energy conservation, efficiency improvement, and process debottlenecking. Many earlier pieces of research have focused on the impact of the network structure and process features such as network topol

Results from the radiological environmental monitoring of the European Spallation Source (ESS) are presented for 2021. Previous zero-point assessments (2017-2020) have mainly focussed on terrestrial samples. New sample types for 2021 include a sediment sample from a pond at the ESS and brown seaweed (Fucus) from Lomma bay and from the east coast of Scania (Skillinge). For gamma-emitting radionucli

Objective: To determine whether a tight control (TC) regime with monthly consultations to the physician for the first 6 months, could increase remission rate and improve reported pain of patients with early rheumatoid arthritis (RA). Methods: In this single-centre, TC study, with monthly visits to the physician, a cohort of 100 patients with early RA was consecutively included. They were compared

Abnormal metabolism of β-amyloid (Aβ) and soluble phosphorylated tau (P-tau), as well as neurodegeneration, are key components of Alzheimer disease (AD), but it is unclear how these different processes are related to genetic risk factors for AD.MethodsIn the Swedish BioFINDER study, we tested associations between a priori defined polygenic risk scores (PRSs) for AD (excluding single-nucleotide pol

We have developed a method for simultaneous tomosynthesis and mechanical imaging, called DBTMI. Mechanical imaging measures the stress distribution over the compressed breast surface. Malignant tissue is usually stiffer than benign, which results in higher stress on the compressed breast and enables to distinguish malignant from benign findings. By combining tomosynthesis and mechanical imaging, w

Abstract: Sexual dimorphism in somatic investment may be shaped by two distinct forms of sexual conflict; under intralocus sexual conflict (IASC), males and females have different optimal levels of somatic investment but are constrained from reaching their respective optima by their shared genome, while under interlocus sexual conflict (IRSC), males and females have different optimal sexual strate

Background: Flexible assertive community treatment (FACT) is an innovative model for providing long-term treatment to people with severe mental illness. The model was developed in the Netherlands but is now used in other countries, including Norway, which has a geography different from the Netherlands, with many rural and remote areas. Implementation of innovations is context dependent. The FACT m

The immunoglobulin genes of inbred mouse strains that are commonly used in models of antibody-mediated human diseases are poorly characterized. This compromises data analysis. To infer the immunoglobulin genes of BALB/c mice, we used long-read SMRT sequencing to amplify VDJ-C sequences from F1 (BALB/c x C57BL/6) hybrid animals. Strain variations were identified in the Ighm and Ighg2b genes, and an