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Explaining dwell time delays with passenger counts for some commuter trains in Stockholm and Tokyo

In both Stockholm and Tokyo, small dwell time delays of at most 5 min make up around 90% of the total delays for commuter trains. To understand these disturbances, we use high resolution data on dwell times and passenger counts from both countries over the last several years. We find that trains in Tokyo are much more congested than in Stockholm, and that the exchange of passengers is modest at mo

Matrix Redox Physiology Governs the Regulation of Plant Mitochondrial Metabolism through Posttranslational Protein Modifications

Mitochondria function as hubs of plant metabolism. Oxidative phosphorylation produces ATP, but it is also a central high-capacity electron sink required by many metabolic pathways that must be flexibly coordinated and integrated. Here, we review the crucial roles of redox-associated posttranslational protein modifications (PTMs) in mitochondrial metabolic regulation. We discuss several major conce

Expansion of the Waste-Based Commodity Frontier: Insights from Sweden and Brazil

Waste is a valuable commodity and remains a livelihood source for waste pickers in the global South. Waste to Energy (WtoE) is often described as alternative to landfilling, as it provides cheap fuel while making waste disappear. In some European cities, this method has evolved into an impediment, slowing down the adoption of more sustainable technologies and waste prevention. These plants typical

Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl clusters-diastereomeric control of enantioselectivity

Twenty clusters of the general formula [(μ-H)2Ru3(μ3-S)(CO)7(μ-P-P∗)] (P-P∗ = chiral diphosphine of the ferrocene-based Walphos or Josiphos families) have been synthesised and characterised. The clusters have been tested as catalysts for asymmetric hydrogenation of tiglic acid [trans-2-methyl-2-butenoic acid]. The observed enantioselectivities and conversion rates strongly support catalysis by int

It will soon be 1984… : Ingemar Ståhl’s pioneering 1979 proposal to abolish cash to strengthen the Swedish welfare state

It is clearly evident from recent developments that government authorities in many respects have failed to gain full control over the citizens of our country. This is especially notable in relation to the problems that have arisen from the spread of so-called grey and black markets and the associated increase in the number of transactions that have evaded taxation. This is not just an efficiency p

Bioaccessibility of phenolic compounds in common beans (Phaseolus vulgaris L.) after in vitro gastrointestinal digestion : A comparison of two cooking procedures

Background and objectives: Beans (Phaseolus vulgaris L.) are widely consumed, but the bioaccessibility of their phenolic compounds (PCs) may be affected by different factors. Within this framework, an in vitro gastrointestinal digestion of two bean varieties: “Azufrado” and “Negro Jamapa,” was performed and the bioaccessibility and in vitro release kinetics of PC was evaluated. Mashed beans were p

Trends and recommendations for critical care nursing research in the Nordic countries : Triangulation of review and survey data

Background: Priorities for critical care nursing research have evolved with societal trends and values. In the 1980s priorities were the nursing workforce, in 1990s technical nursing, in 2000s evidence-based nursing and in 2010s symptom management and family-centred care. Objectives: To identify current trends and future recommendations for critical care nursing research in the Nordic countries. M

Is it possible to feel at home in a patient room in an intensive care unit? Reflections on environmental aspects in technology-dense environments

This paper focuses on the patient's perspective and the philosophical underpinnings that support what might be considered optimal for the future design of the intensive care unit (ICU) patient room. It also addresses the question of whether the aspects that support at-homeness are applicable to ICU patient rooms. The concept of “at-homeness” in ICUs is strongly related to privacy and control of sp

Family members’ experiences of waiting in intensive care : a concept analysis

Aim: The aim of this study was to explore the meaning of family members’ experience of waiting in an intensive care context using Rodgers’ evolutionary method of concept analysis. Method: Systematic searches in CINAHL and PubMed retrieved 38 articles which illustrated the waiting experienced by family members in an intensive care context. Rodgers’ evolutionary method of concept analysis was applie

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

Botulinum neurotoxins (BoNTs) are a family of bacterial toxins with seven major serotypes (BoNT/A-G). The ability of these toxins to target and bind to motor nerve terminals is a key factor determining their potency and efficacy. Among these toxins, BoNT/B is one of the two types approved for medical and cosmetic uses. Besides binding to well-established receptors, an extended loop in the C-termin

pH dependence of aqueous oxalic acid observed by X-ray absorption and emission spectroscopy

In this work, X-ray absorption spectroscopy (XAS) and site-selective X-ray emission spectroscopy (XES) were used to measure the oxygen K-edge (OC=O,1s and OCO − ,1s) of oxalic acid, with theoretical calculations performed to reproduce the spectra observed. Structure sampling of a cluster model was performed using an ab initio molecular dynamics trajectory. Relative XES intensities from core-hole e

An Identity Privacy Preserving IoT Data Protection Scheme for Cloud Based Analytics

Efficient protection of huge amount of IoT produced data is key for wide scale data analytic services. The most efficient way is to use pure symmetric encryption as that allows both fast decryption at the analytic engine side as well as energy efficient encryption at the IoT side. However, symmetric encryption can only be performed if there is a way to directly map an encrypted object to the corre

Tomographic reconstruction with a generative adversarial network

This paper presents a deep learning algorithm for tomographic reconstruction (GANrec). The algorithm uses a generative adversarial network (GAN) to solve the inverse of the Radon transform directly. It works for independent sinograms without additional training steps. The GAN has been developed to fit the input sinogram with the model sinogram generated from the predicted reconstruction. Good qual

Global RNA expression and DNA methylation patterns in primary anaplastic thyroid cancer

Anaplastic thyroid cancer (ATC) is one of the most malignant tumors, with a median survival of only a few months. The tumorigenic processes of this disease have not yet been completely unraveled. Here, we report an mRNA expression and DNA methylation analysis of fourteen primary ATCs. ATCs clustered separately from normal thyroid tissue in unsupervised analyses, both by RNA expression and by DNA m

Struggling, settling, solutions : A qualitative study of landscape protection in motorway planning

Landscape is an important public interest with social, cultural, ecological, and environmental dimensions. It is central to the formation of local cultures and contributes to human well-being. Some areas are protected by supranational agreements that have significant international value. The European Landscape Convention (ELC) calls for integrating landscape considerations into other policy areas

Two routes for extracellular electron transfer in Enterococcus faecalis

Enterococcus faecalis cells are known to have ferric reductase activity and the ability to transfer electrons generated in metabolism to the external environment. We have isolated mutants defective in ferric reductase activity and studied their electron transfer properties to electrodes mediated by ferric ions and an osmium complex modified redox polymer (OsRP), respectively. Electron transfer med

An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders

Cerebrospinal fluid analyses and neuroimaging can identify the underlying pathophysiology at the earliest stage of some neurodegenerative disorders, but do not have the scalability needed for population screening. Therefore, a blood-based marker for such pathophysiology would have greater utility in a primary care setting and in eligibility screening for clinical trials. Rapid advances in ultra-se

The World is a Prison to Believers : Naming and Worlds in Malcolm X

In this paper, we look at the terrain of Malcolm X's "failed rhetoric" as producing an apocalyptic refusal of world, and world making. This refusal finds its intensity from a distinct gnostic calculus, driving Malcolm X's political theology of names and worlds, seen in his oratory from the years 1962–1964. First, Malcolm X's nominal history is discussed in relation to the violence of naming and po

Socioeconomic status and survival after stroke - Using mediation and sensitivity analyses to assess the effect of stroke severity and unmeasured confounding

Background: Although it has been established that low socioeconomic status is linked to increased risk of death after stroke, the mechanisms behind this link are still unclear. In this study we aim to shed light on the relationship between income level and survival after stroke by investigating the extent to which differences in stroke severity account for differences in survival. Methods: The stu