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It is well known that one fragility fracture begets another. Fracture Liaison Services have been shown to narrow the care gap that exists in the care of patients with fragility fractures. A secondary fracture prevention programme "OPTIMAL" (Osteoporosis Patient Targeted and Integrated Management for Active Living) has been in existence in the public restructured hospitals and polyclinics of Singap
Ceruloplasmin, a ferroxidase present in cerebrospinal fluid (CSF), plays a role in iron homeostasis protecting tissues from oxidative damage. Its reduced enzymatic activity was reported in Parkinson's disease (PD) contributing to the pathological iron accumulation. We previously showed that ceruloplasmin is modified by oxidation in vivo, and, in addition, in vitro by deamidation of specific NGR-mo
Background: Unilateral vestibular deafferentation (uVD), as performed in vestibular schwannoma surgery, results in a chronic vestibular deficit, though most of the insufficiency can be compensated by other sensory input. By vestibular training (prehabituation) performed before surgery, motor adaptation processes can be instigated before the actual lesion. The adaptation processes of the altered se
We present a Bayesian ideal observer model that estimates observer translation and rotation from optic flow and an extra-retinal eye movement signal. The model assumes a rigid environment and noise in velocity measurements, and that eye movement provides a probabilistic cue for rotation. The model can simulate human heading perception across a range of conditions, including: translation with simul
In this study, 10 hematologists and 10 lung oncologists were interviewed regarding the information they provide to patients in four situations of uncertainty: determining the treatment that is in the patient's best interest; recurrence or progression of the patient's disease; determining when to withdraw life-prolonging treatment; discussing death, addressing questions such as whether the patient
This paper presents the co-design of a class-D digitally-controlled oscillator (DCO) and a low-dropout voltage regulator (LDO) generating the supply voltage for the DCO. Despite the high intrinsic supply pushing of the class-D oscillator topology, the LDO noise has only a very marginal impact on the DCO phase noise. The class-D DCO and LDO have been integrated in a 65nm CMOS process without any th
Popular Abstract in Swedish Mikroti är en medfödd avvikelse där ytterörat inte utvecklats normalt. Defekten kan variera från att örat nästan är normalt till att det saknas helt och hållet, s.k. anoti. I Sverige inträffar detta i c:a 2 fall per 100 000 nyfödda. Pojkar drabbas i större utsträckning och höger sida är den vanligaste. Båda sidor drabbas i c:a en tiondel av fallen. Förträngning av yttreMicrotia is a congenital malformation where the auricle is not fully developed. In some cases the malformation is complete and the auricle is absent. In Sweden the incidence of microtia is about 2 per 10,000 births. Reconstruction of the external ear is possible by using autologous rib cartilage in three surgical steps: rib cartilage transplantation, ear elevation and final adjustments. Although t
A measurement of the production cross-section for top quark pairs (t (t) over bar) in pp collisions at root s = 7 TeV is presented using data recorded with the ATLAS detector at the Large Hadron Collider. Events are selected in two different topologies: single lepton (electron e or muon mu) with large missing transverse energy and at least four jets, and dilepton (ee, mu mu or e mu) with large mis
Moths depend on pheromone communication for mate finding and synthetic pheromones are used for monitoring or disruption of pheromone communication in pest insects. Here we produce moth sex pheromone, using Nicotiana benthamiana as a plant factory, by transient expression of up to four genes coding for consecutive biosynthetic steps. We specifically produce multicomponent sex pheromones for two spe
Background: In European countries, knowledge about availability and utilization of support for informal caregivers caring for older persons (>= 65 years) with dementia (PwD) is lacking. To be able to evaluate and develop the dementia support system for informal caregivers to PwD, a survey of European support systems and professionals involved is needed. The aim of this study was to explore support
Lion fecal DNA extracts from four individuals each from Yankari Game Reserve and Kainji-Lake National Park (central northeast and west Nigeria, respectively) were Sanger-sequenced for the mitochondrial cytochrome b gene. The sequences were aligned against 61 lion reference sequences from other parts of Africa and India. The sequence data were analyzed further for the construction of phylogenetic t
Northern high-latitude wetlands are well known to seasonally emit methane gas into the atmosphere, and therefore contribute to greenhouse effects. While these gas emissions are well documented, their causes are not well understood. The method described in this work can be used to analyze the changes happening in the soil during gas emissions, and therefore help the understanding of the sub-surface
Popular Abstract in Swedish Det är känt att kvalitén på inomhusluften har en avgörande betydelse för folkhälsan bla avseende astma, eksem samt luftvägsinfektioner. Detta är ett för samhället mycket kostsamt problem. I avhandlingen har studerats vissa luftföroreningar inomhus som kan bli följden av att en byggnad drabbats av fuktskada. När fukt påverkar byggnadsmaterial frigörs och bildas en rad oUnsatisfactory indoor air quality (IAQ) may result from polluting emissions that are spread from building materials such as volatile organic compounds (VOCs) and/or microbial components or from various kinds of human activity such as smoking. Different methods are available to limit the exposure to unwanted pollutants and improve human wellbeing and health. One goal of this thesis was to determine
This paper presents a model of long waves and an empirical analysis of Swedish growth since 1850. The model emphasises the creation of new complementarities around macro innovations. The growth process is periodised in two main parts. The first period is characterised by transformation when development is uneven and unbalanced. The second period is characterised by rationalisation when the economy
There is an urgent need to start generating energy within cities in order to pave the way for a more sustainable and resilient society. Renewable energy by means of active solar energy systems (solar thermal, ST and/or photovoltaics, PV) can be generated using roofs and facades of buildings. In this study, the annual solar energy potential of typical Swedish city blocks was analysed in order to de
A dynamic model of forest ecosystems was used to investigate the effects of climate change, atmospheric deposition and harvest intensity on 48 forest sites in Sweden (n = 16) and Switzerland (n = 32). The model was used to investigate the feasibility of deriving critical loads for nitrogen (N) deposition based on changes in plant community composition. The simulations show that climate and atmosph
Effects of a dietary combination of omega-3 polyunsaturated fatty acids (n-3-PUFA) and conjugated linoleic acids (CLAs) on fasting and postprandial plasma lipids was investigated in healthy volunteers with different ages and body mass index (BMI). Lean (BMI 20-26 kg/m2) and obese (BMI 29-35 kg/m2), young (20-37 years) and older (50-65 years) men consumed 3 g/day each of CLA and n-3-PUFA or 6 g/day
