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The Three Axial Perineal Evaluation (TAPE) score : A new scoring system for comprehensive evaluation of pelvic floor function

Aim: Abnormalities of one pelvic floor compartment are usually associated with anomalies in the other compartments. Therapies which specifically address one clinical problem may potentially adversely affect other pelvic floor activities. A new comprehensive holistic scoring system defining global pelvic function is presented. Method: A novel scoring system with a software program is presented expr

The impact of lymph vascular space invasion on recurrence and survival in patients with early stage endometrial cancer

The aim of this study was to determine impact of lymph vascular space involvement (LVSI) on recurrence and survival in early stage of endometrial cancer. From 1991 through 2010, all endometrial cancer patients at University Hospital of Bari, Italy were identified. The Log-rank test and Kaplan-Meyer methods were used for time-to-event analysis to evaluate the effects of on lymph vascular space invo

Bowel dysfunction following nerve-sparing radical hysterectomy for cervical cancer : A prospective study

Objective: To objectively assess anorectal dysfunction following nerve-sparing radical hysterectomy in stage I-II cervical carcinoma patients. Material and Methods: Between 2008 and 2012, 21 patients with primary cervical cancer stage FIGO I-II were enrolled in this prospective study. All women underwent nerve-sparing radical hysterectomy. Anorectal manometry was performed preoperatively and 6 mon

CADdy - Colposcopy learning machine for computer aided diagnosis

The study and development of a decision support system for doctors and students is presented, aiming to ease the diagnosis of the cervix cancer through an automated smart system: using a web application, a medical expert can upload colposcopic images feeding an expert system that carries out a deep analysis by a processing system on images uploaded by doctors; results coming out of the processing

Changes in the management and outcome of central nervous system involvement from ovarian cancer since 1994

Objective: To identify differences in the management and outcome of patients with central nervous system metastases from epithelial ovarian cancer. Methods: The clinical and pathologic characteristics, treatment, and outcome of 23 patients with brain metastases from epithelial ovarian cancer who were treated during 1982-1994 were compared with those of 20 patients treated during 1995-2010 at the s

Prognostic factors and outcomes in 28 cases of uterine leiomyosarcoma

Objectives: It was the aim of this study to evaluate clinicopathological characteristics and prognostic factors of uterine leiomyosarcomas (LMS). Methods: Twenty-eight patients with uterine LMS were evaluated in this retrospective study. Their features and survival were analyzed by Kaplan-Meier and log-rank tests. Results: The median age of the patients was 52 years (range 25-74). Nine patients ha

Central nervous system metastases from epithelial ovarian cancer : Prognostic factors and outcome

Objectives: To analyze the clinicopathological characteristics and prognostic factors associated with survival in patients with central nervous system (CNS) metastases from epithelial ovarian cancer. Methods: Twenty patients with CNS involvement from ovarian carcinoma were evaluated in this retrospective study; their features and survivals were analyzed using Kaplan-Meier and log-rank test methods

Carcinosarcoma of the ovary : Analysis of 13 cases and review of the literature

Objectives: The aim of this study was to evaluate our experience with patients affected by ovarian carcinosarcoma. Patients and Methods: During a 16-year period, data on 13 patients with ovarian carcinosarcoma were collected. They were obtained from hospital charts and follow-up visits. Survival curves were estimated by the Kaplan-Meier method and compared using the log-rank test. All tests were t

Investigating Critical Friendship: Peeling Back the Layers

This self-study documents two teacher educators’ professionalinquiry into the notions of critical friendship. Specifically, we asked:How does our interactive inquiry on the topic of critical friendshiplead us to new understandings of critical friends? Three theoreticalperspectives framed this study – More Knowledgeable Others,Thought Collective, and reflection. Data sources included (a) artifactsfThis self-study documents two teacher educators’ professional inquiry into the notions of critical friendship. Specifically, we asked: How does our interactive inquiry on the topic of critical friendship lead us to new understandings of critical friends? Three theoretical perspectives framed this study – More Knowledgeable Others, Thought Collective, and reflection. Data sources included (a) artif

Nuclear disaster as chronic crisis : Accounts of radiation embodiment by survivors of the Chernobyl nuclear disaster from Belarus born before, in and after 1986

This article looks at chronic crisis on an empirical example of radiation embodiment by survivors of a nuclear disaster. Developing further the work of Henrik Vigh, this article argues that chronic crisis is conflictual in nature, where some individuals fully embrace it, while others reject it. A total of 16 in-depth interviews were conducted with survivors of the Chernobyl nuclear disaster from B

Reduced workforce participation 5 years prior to first Parkinson’s disease sick-leave

The importance of understanding the prodromal phase of Parkinson’s disease (PD) by systematic recording of prediagnostic symptoms and reductions in body functions has been highlighted. The aim of this study was to investigate whether persons later diagnosed with PD exhibit increased physician-certified sickness absence 1, 2, and 5 years prior to a first sick-leave episode attributed to PD. A case-

Motivations and mechanisms for the development of the reactive what-x construction in spoken dialogue

With data from two comparable corpora of spoken British English, the London-Lund Corpus and the new London-Lund Corpus 2, this study tracks the development of the reactive what-x construction half a century back in time. The study has two goals: (i) to describe the uses of the construction over time and (ii) to establish the motivations and mechanisms related to its development in spoken dialogue.

Atomic Layer Deposition and Immobilised Molecular Catalysts Studied by In and Ex Situ Electron Spectroscopy

Popular ScienceThe growing need for green processes in industry makes scientists design and develop processes that are more energy efficient than current processes. Naturally, some reactions require a high energy and long time to occur. This will cause high energy consumption and, typically, even more waste production. Therefore, many efforts have been done to design materials that can help to chaThe research work that I describe in my thesis deals with three different heterogenisation approaches for synthesising a heterogeneous transition metal catalyst used for direct C-H activation reactions. The three heterogenisation approaches considered in my research are: (1) heterogenisation of a molecular catalyst on a polymer support using covalent bonds, (2) heterogenisation of a catalyst on a

Recognition and Separation of Hemoglobin Variants via Molecularly Imprinted Polymers

Hemoglobin (Hb) is the predominant protein in red blood cells with allosteric regulation mechanisms for delivering oxygen between the lungs and tissues. After the 1980s, concentrated research on modified Hb emerged because of the necessity for the development of a blood substitute (oxygen carrier). Several purification procedures and genetic/chemical modifications of Hb have been undertaken by bot