The effect of RNA binding proteins on the regulation of Human papillomavirus type 16 late gene expression
In this paper, we addressed whether cellular RNA binding proteins TIAR, hnRNP C1 and HuR induce HPV 16 late gene expression by interacting with elements of the viral genome that regulate splicing and polyadenylation. Pathogenesis and progression to HPV infected lesion is regulated by the viral gene expression program and it has been previously shown that several RNA binding proteins have an effect