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PURPOSE. Pre-mRNA processing factor 31 (PRPF31) is a ubiquitous protein needed for the assembly of the pre-mRNA splicing machinery. It has been shown that mutations in this gene cause autosomal dominant retinitis pigmentosa 11 (RP11), which is characterized by rod-cell degeneration. Interestingly, mutations in this ubiquitously expressed gene do not lead to phenotypes other than retinal malfunctio

Detta working-paper kom till efter att företrädare inom Individ och familjeomsorgen i Hässleholms kommun ville effektutvärdera sin familjeverksamhet. Ett samarbete påbörjades mellan Socialhögskolan och Familjebehandlingsenheten i Hässleholm.Papret är ett försök att genom föra små effektstudier i hög vetenskaplig design. Det finns flera små behandlingsenheter inom socialförvaltningar runt om i Sver

This paper compares the capacity improvement capability of spatial multiplexing and beamforming techniques for 60 GHz spatial transmissions in a multi-carrier radio system such as orthogonal frequency division multiplexing. The term beamforming in this paper refers to the conventional gain focusing, for the strongest propagation path, by narrow antenna beams. Our channel capacity metric depends on

Gamma rays from the decay of an isomer in W-190(116) have been observed following projectile fragmentation of a 1 GeV per nucleon Pb-208 beam. An earlier experiment indicated decay from a (10(-)) isomer to the ground state rotational band. Improved statistics have enabled gamma coincidence and time-difference measurements to be made which alter the previous interpretation. Blocked BCS calculations

Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT.

The production of the strange and double-strange baryon resonances (Sigma (1385)(+/-), Xi (1530)(0)) has been measured at mid-rapidity (vertical bar y vertical bar < 0.5) in proton-proton collisions at root s = 7 TeV with the ALICE detector at the LHC. Transverse momentum spectra for inelastic collisions are compared to QCD-inspired models, which in general underpredict the data. A search for the

Based on high-resolution spectra obtained during gravitational microlensing events we present a detailed elemental abundance analysis of 32 dwarf and subgiant stars in the Galactic bulge. Combined with the sample of 26 stars from the previous papers in this series, we now have 58 microlensed bulge dwarfs and subgiants that have been homogeneously analysed. The main characteristics of the sample an

The politics of European collaborative Big Science are inherently uncertain. The European Spallation Source (ESS) for materials science, planned to be built in Sweden with a collaborative European funding solution that was recently finalized is the most recent example. Sweden has so far invested around one billion SEK (&E110 million), taking a significant risk given these uncertainties and giv

Managing risk using an “all-hazards” and “whole of society”-approach involves extensive communication of risk descriptions among many stakeholders. In the present study we investigate how professionals working with disaster risk management in such contexts perceive the usefulness of different descriptions of risk. Empirical data from the Swedish disaster risk management system were used in an atte

Background: Pediatric intestinal biopsy procedures including considerable transpharyngeal manipulation of a wire-guided metal capsule require adequate sedation or anesthesia. This retrospective cohort study was designed to evaluate intravenous sedation with ketamine and low-dose midazolam in young children undergoing these procedures before and also after discharge from the hospital. Methods: A t

This article investigates whether public funds should support R&D and if so, how such support should be designed in order to be efficient and to comply with the legal requirements stated in EU law and in domestic budget law. The article puts the emphasis on tax expenditure and, in particular, on tax incentives. The findings show that Member States should only subsidize projects where the socia

Urban water management policy in Japan, with examples from Fukuoka city, is described and the potential for sustainability of Fukuoka's urban water system is discussed. A framework of the qualitative characteristics of a sustainable system (including social, environmental and economic factors) is developed and used in the analyses presented here. The Fukuoka example shows that technically advanced

Cement hydration needs water to proceed and if water is lost by drying, the hydration rate will decrease This can be of importance in cases when concrete surfaces are exposed to drying so that their strength development will be retarded We describe a method based on isothermal calorimetry to assess how the rate of cement hydration is influenced by removal of water (drying) at different times up to

Customers are important stakeholders for any company; yet, they seem not to be widely discussed in merger and acquisition research. This chapter synthesizes the current body of research on customers in mergers and acquisitions through presenting a systematic literature review. The chapter is based on a systematic literature review resulting from a search in EBSCO Host for any research item that re

Popular Abstract in Swedish Partiella differentialekvationerna} är kraftfulla verktyg som kan användas för att beskriva fysikaliska fenomen inom bland annat naturvetenskap, teknik, ekonomi och medicin. Listan med tillämpningar kan göras hur lång som helst: Partiella differentialekvationer kan beskriva hur en snöflinga bildas, hur strukturer deformeras när de utsätts för mekaniska krafter, hur blodSplitting methods are widely used as temporal discretizations of evolution equations. Such methods usually constitute competitive choices whenever a vector field can be split into a sum of two or more parts that each generates a flow easier to compute or approximate than the flow of the sum. In the research presented in this Licentiate thesis we consider dissipative evolution equations with vector