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Anna Sundgren, MOBM02 September 23 - January 24, Department of Biology, Lund University Baby infection as Alzheimer´s disease protection? The characteristic pathology of Alzheimer’s disease (AD) includes accumulation of amyloid-beta protein as plaques, and tau-protein as tangles in the brain. Another important feature of the disease is neuroinflammation. One important risk gene for AD is the apo
This study aimed to investigate various properties associated with human protein deletions, encompassing deletion length and position, amino acid composition, flanking amino acid composition, functions of the host proteins, the functional role of the corresponding gene, relative positioning with protein domains, protein structure within the deletion region, and conservation, to identify potential
Bakgrund: Meningsfulla aktiviteter är sammankopplade med hälsa och välbefinnande. När människor åldras eller deras förutsättningar för aktivitet förändras kan förlusten av meningsfulla aktiviteter leda till ohälsa. Äldre personer kan både förlora förmågan att utföra aktiviteter, men också finna att förutsättningar till aktivitetsutförande förändras när hemmiljö och äldreboende blir ett. Syfte: SyfBackground: Meaningful activities are interconnected with health and well-being. When people age or their circumstances for engaging in occupations change, a loss of meaningful activities can occur, leading to illness. Older people may not only lose the ability to perform occupations but may also find that their circumstances for engaging in occupations change when the home environment and nursing
Inom vägbyggnad har det skett minimala förändringar av byggmetodiken sedan det romerska imperiets tid, detta fram till att McAdam dök upp. McAdams filosofi handlade om att bygga en ogenomtränglig och upphöjd överbyggnad i förhållande till de omgivande ytorna för att minimera vatteneffekterna på konstruktionen. Med hänsyn till dagens klimatförändringar krävs dock implementering av nyare konstruktioIn road construction there have been minimal changes to the construction since the time of the Roman empire, until the time of McAdam. McAdam’s philosophy included an impermeable and raised superstructure in relation to the surrounding surfaces to minimize the water effects on the construction. In view of today's challenges with climate change, however, new thinking is required in road constru
RNA-seq has become a revolutionary tool for genome-wide gene expression analysis, opening new possibilities for research. This study focuses on using RNA-seq data for variant calling at Single Nucleotide Polymorphisms in a non-model organism, the bank vole. Variant calling from RNA-seq can for example be used for Allele-Specific Expression (ASE) analysis which sheds light on the impact of genetic
Nedbrytarsvamparnas arvsmassa ger oss ökad kunskap om deras Livsstil Saprotrofiska nedbrytarsvampar spelar en mycket viktig roll i kolets kretslopp. De får näring och energi genom att bryta ned dött växtmaterial i marken, till exempel döda kvistar och löven som faller på hösten. I nedbrytningsprocessen frigörs kol och andra näringsämnen som tas upp av svamparna, men kol avges även till atmosfären
En insektshjärna i ett kräftdjur Alla djur navigerar på något sätt. Men hur navigerar de, vad använder olika djur för att navigera genom världen? Det kan till synes verka som en trivial sak, bara gå i rätt riktning. Men hur vet man vad som är rätt riktning? Det har visat sig att det finns många olika sätt att veta om man ’navigerar rätt’. Insekter framför allt använder sig av alla möjliga typer aThe Central Complex (CX) is a highly conserved brain region at the center of the arthropod brain. It is believed to be the navigational center with a special neural circuit called the head direction system. The head direction system is the neural basis for a typical navigational strategy called path integration. Path integration requires the animal to have an external compass like the sun and an i
This thesis is dedicated to exploring and understanding public reactions within negotiated peace settlements based on social media data. Concretely, to modeling public opinion and sentiment within the context of the Colombian peace process using a curated dataset of N= ~1.3 million user comments expressing discord on 15,509 Facebook posts, throughout three years (2020-2022). A critical period embr
Food availability is known to influence animal distribution and abundance, playing a crucial role in population dynamics. However, this correlation remains somewhat unclear due to interactions with several other factors such as climate, predation pressure, competition, or even human influence. Therefore, understanding the mechanisms underlying these processes is crucial for ecologists to effective
Arvegods armchair which has its roots in the sustainable design tradition, is a journey through the eternal appeal of locally sourced materials. Bringing inspiration from the enduring bonds we create with treasured items, the user incorporate handcrafted linen textiles that evoke sentiments of love and workmanship from generations. The design encourages users to incorporate their own stories into
High-order Harmonic Generation (HHG) is a highly non-linear process in which an atom interacts with a strong laser field. The laser field lowers the atomic potential barrier allowing bound electrons to escape into the continuum through tunnel ionization, propagate, and, with some probability, recombine with the parent ion. As a result, coherent eXtreme UltraViolet (XUV) radiation is emitted in the
The Jordanian Christian community is, in many aspects, a unique case within the MENA region. Mostly neglected by scholars and the mainstream public alike, it is perceived as unproblematic due to the institutional guarantees granted by the Hashemite regime, and the absence of apparent existential threats. Nonetheless, the copious influx of refugees from neighboring “sectarianized” contexts, the alw
Avståndet mellan produktion och konsumtion av livsmedel är långt. Dagens komplexa matsystem har försvagat vår relation till råvarors ursprung och dess värde. Industrier hamnar allt längre bort i periferin och blir otillgängliga för stadens invånare. Med växande befolkning och ökat livsmedelsbehov krävs alternativa och transparenta former av matsystem som grundar sig i naturens egna processer. TåThe distance between production and consumption of food is big. Today’s complex food systems have weakened our relationship with the source of raw materials and its value. Industries end up the periphery and becoming unaccessible to people in the city. With a growing population and increased food demand, alternative and transparent forms of food systems are required, grounded in nature’s own proce
Debatten om en hejdlös rivningskultur i Sverige har börjat ta fart de senaste åren. Utöver samtidens klimatfrågor som präglat kritiken om resursslöseri och utsläpp har även röster börjat höjas för historiska och kulturella värden som går förlorade. Viljan och förmågan att bevara befintlig arkitektur i Sverige har inte varit stark historiskt sett och fortsätter inte heller att vara det i vår samtidThe debate concerning the widespread demolition-culture in Sweden has sparked during recent years. Beside questions regarding climate change, waste of resources and emissions, voices have also started to rise for the historic and cultural values that are being lost. The will and capability to preserve existing architecture in Sweden hasn’t been strong historically and continues not to be so in mod
A semi-analytical simulation was developed to evaluate the K-band magnitudes of Red Giants [0.96 - 1.02 M⊙] orbiting the supermassive black hole in the galactic centre. The model assumed star formation between 10-12 Gyrs ago and by following the IMF and applying a random age condition, a stellar population was created. It was established that stars with mK ≤ 16 can be observed and then they become
Maarten van Heemskerck’s St. Lawrence Altarpiece came to Sweden and Linköping Cathedral in the early 1580s. Around 50 years later, its design was copied by Johan Werner the elder for the altarpiece in Skänninge Vårfrukyrka, within the same diocese. The aim of this thesis is to map and contextualize discrepancies between the two altarpieces, doing so with the following research question: What diffe
Introduction: Phlorotannins, bioactive natural phenolic polymer, existing in mostly brown seaweeds have been commonly quantified through colorimetric methods. Background: Colorimetric methods such as Folin-Ciocalteu (F-C) and 2,4- dimethoxybenzaldehyde (DMBA) assays have been widely used for total phlorotannins content (TPC) estimation. Aim(s): The aim of this study was to compare two different
Title Powering Tomorrow - Implementation of Battery Energy Storage System in today's Power Grid Authors Henrik Ramström and Krenar Gerxhaliu Supervisor Ingela Elofsson, Dept. of Production Management, Faculty of Engineering, Lund University Maricruz Bravo, Flower Infrastructure Technologies AB Background We are currently undergoing a transition in the industrial development, taking plac
This project looks at the potential of integrating the human perception and specifically our own perception of scent into the design process. To create something unique, valuable and potentially tangible with a powerful perception that is the exact opposite, intangible. In my Thesis I explored different uses cases, went on a sensual experiences myself to encounter the enriching potential,
