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Single-step affinity purification, partial structure and properties of human platelet cGMP inhibited cAMP phosphodiesterase

The human platelet cilostamide- and cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) was rapidly purified approximately 19,000-fold to apparent homogeneity using single step affinity chromatography on the isothiocyanate derivative of cilostamide coupled to aminoethyl agarose. Within 24 h, 30 micrograms of enzyme protein was obtained from 20 ml of packed platelets. Vmax for cAMP and cGMP was 6.1 and

Prognostic significance of elevated creatine kinase MB after coronary bypass surgery and after an acute coronary syndrome: Results from the GUARDIAN trial

Objective: To determine if the correlation between magnitude of creatine kinase-myocardial band release after coronary artery bypass surgery and 6-month mortality is comparable to that of patients admitted with an acute coronary syndrome. Methods: The GUARDIAN trial tested the efficacy of cariporide, an Na+/H+ exchange inhibitor, on reduction of myocardial ischemia or death in high-risk patients.

NaK photoabsorption and resonant KLL Auger spectra in naf and NaCl

The nature of Na Is photoabsorption in NaF and NaCl is investigated using the resonant Auger decay of Na Is core excitations. The appearance of new peaks in Auger spectra, when the energy of excitation coincides with the photoabsorption thresholds, shows that the core excitons are created in the threshold region of the Na 1s photoabsorption spectrum. The core excitons around 1074.2 eV originate fr

Densities of large living and dead trees in old-growth temperate and boreal forests

We recorded and reviewed densities and basal areas of large living and dead trees in old-growth forest in Europe. Recorded densities were similar to those reported from old-growth forests in eastern North America, but lower than in northwestem North America. Based on our results we suggest that, 10-20 living trees per ha with dbh > 70 cm may have been typical values for many central European and s

Experimental and Clinical Studies on Platelet Receptors in Cardiovascular Disease

The crucial role of platelets in maintaining primary hemostais has been evident for a long time and there is now also mounting evidence for their involvement in inflammation. In combination with aspirin, inhibition of the platelet P2Y12 ADP receptor with clopidogrel has become a cornerstone in the antiplatelet in acute coronary syndromes. Recently, several studies have indicated that a considerabl

Hair element concentrations in females in one acid and one alkaline area in southern Sweden.

Concentrations of 34 trace elements in hair have been determined in 47 females from an acid region in southern Sweden, who were compared with 43 females from an alkaline area. The concentrations of these elements in hair and drinking water were determined by inductively coupled plasma optical emission spectroscopy and inductively coupled plasma mass spectrometry. The hair concentrations of boron a

Nordisk katolicism : katolsk mission och konversion i Danmark i ett nordiskt perspektiv

This book, which is the result of my work within the project Conversion and Change of Confession, deals with Catholic mission and conversion in Scandinavia in the 19th and 20th cetries. I focus on Denmark, but the Danish situation is studied in a comparative Nordic pespective and against the background of the general religious, ideological and church-political development at the time. Up to the Se

Reactive dc magnetron sputter deposited Al2O3: large area coatings for industrial application

Stoichiometric Al2O3 films are produced with a pure Al source in the metallic state in an O2+Ar gas mixture using reactive d.c. magnetron sputtering. Substrates as large as 70×100 cm2 are uniformly coated at room temperature while moving in front of the cathode. The key to the success lies in utilizing a sufficiently high working gas pressure and a sufficiently large source-to-substrate distance.

Just-in-Time : Hur industriella rationaliseringsstrategier formar arbetsdelning och kompetens

The emergence of new modes of production, referred to as flexible specialization, post-Fordism or neo-Fordism, has played an important and controversial role in the debate among economic geographers and industrial sociologists. In the discussion assumptions have been made about a process of up-skilling of the work force. In this study a random sample of 351 white- and blue-collar workers in eight

Phosphonation of polysulfones via lithiation and reaction with chlorophosphonic acid esters

A noncatalytic route for the phosphonation of polysulfones was established in which lithiated sites on polysulfones were reacted with an excess of chlorophosphonic acid esters through an SNP(V) mechanism. Both the bisphenol A and biphenyl sulfone segments of the polysulfone main chain were modified according to whether brominated polysulfone or pristine polysulfone was used. Up to 50% of the repea

Sonography in total hip arthroplasty

Purpose: The distance between the anterior surface of the neck of the prosthetic stem and the anterior joint capsule, the "capsular distance", is increased in total hip arthroplasty (THA) with synovitis. We evaluated the potential of ultrasonography (US) in measuring the "capsular distance" in THA hips one year after insertion. Materials and Methods: We compared the measurements of the capsular di

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Popular Abstract in Swedish Denna avhandling bygger på en korpus (Corpus Jabet) av intervjuer som genomfördes med vuxna talare 1996 i Abidjan, Elfenbenskustens största stad och ekonomiska medelpunkt. Informanterna har delats in i tre grupper efter sociolingvistiska kriterier, där skolgång med franska som undervisningsspråk är det väsentligaste: ingen eller ytterst lite skolgång (Grupp A1), avslutaThis study examines the omission of the article and of the subject pronoun in the spoken French of Abidjan, economic capital of Côte d'Ivoire. The occurrence of the bare nouns (NSDs for Noms Sans Déterminant) and subject-less tensed verbs (SujNuls for Sujets Nuls) in question is contrary to common use in standard as well as ordinary French. The findings made show that both kinds of omissions are