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Structural basis of glycosaminoglycan modification and of heterotypic interactions of perlecan domain V

The C-terminal perlecan domain V of about 90 kDa consists of laminin-type G domain modules (LG) (25 kDa) and epidermal growth factor-like modules (EG) (4 kDa) in the tandem arrangement LG1-EG1-EG2-LG2-EG3-EG4-LG3. Several shorter fragments have been prepared by recombinant production in mammalian cells and used to map the single glycosaminoglycan (GAG) substitution site and the binding of several

A model for stochastic drift in memory strength to account for judgments of learning

Previous research has shown that judgments of learning (JOLs) made immediately after encoding have a low correlation with actual cued-recall performance, whereas the correlation is high for delayed,judgments. In this article, the authors propose a formal theory describing the stochastic drift of memory strength over the retention interval to account for the delayed-JOL effect. This is done by firs

Direct evidence of defect annihilation during structural relaxation of amorphous indium phosphide

Extended x-ray absorption fine structure measurements have been used to characterize the low-temperature, thermally induced structural relaxation of amorphous InP. We show reductions in both chemical and structural disorder associated with homopolar and heteropolar bonding, respectively, are operative during structural relaxation of this amorphous compound semiconductor. The latter is analogous to

Contribution of religiousness in the prediction and interpretation of mystical experiences in a sensory deprivation context: Activation of religious schemas

M. A. Persinger (2002) claimed that transcranial magnetic stimulation with weak, complex magnetic fields evokes mystical experiences. However, in a double-blind experiment, P. Granqvist, M. Fredrikson, P. Unge, A. Hagenfeldt, S. Valind., et al. (2005) found no effects of field exposure on mystical experiences (N = 89), though a minority of participants reported spontaneous mystical experiences. Fo

Sheep and goat in Norse Paganism

Sheep and goats are some of the most important animals in prehistoric Scandinavia. The habitus of the animals was used and transformed into cultural categories. Owing to their important and long-term utility they were ritualised during the pre-Christian periods. The role of these animals and the attitudes towards them in and beyond Norse paganism is discussed with habitus perspectives applied to t

Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death.

AIMS: To compare the incidence of myocardial infarction and death in non-diabetic subjects with and without insulin resistance. METHODS: Population-based prospective cohort study, in Malmö, Sweden, of 4748 non-diabetic subjects (60% women), aged 46-68 years, with no history of myocardial infarction or stroke. The prevalence of insulin resistance was established by the homeostasis model assessment

High-order laser guide star performance for the Euro50 telescope

High-order laser guide star performance for the Euro50 telescope is analyzed. Focus anisoplanatism residual errors using multiple LGSs are obtained by numerical simulations. Results calculated for annual mean conditions at the La Palma site show that, considering only focus anisoplanatism, it will be possible to obtain a Strehl ratio of 0.72 similar to 0.82 at 2.2 mum using 13 LGSs. A Strehl ratio

Association between low concentrations of antibodies to protein alpha and Rib and invasive neonatal group B streptococcal infection

Background: Infection with group B streptococci (GBS) is a serious neonatal disease. The GBS cell surface proteins a and Rib elicit protective immunity in animal models and have been suggested as potential antigens in a vaccine against human GBS disease. Aims: To test the hypothesis that transplacentally transferred maternal antibodies to GBS proteins contribute to the protection of the neonate fr

Education, Labor Force Participation and Changing Fertility Patterns. A Study of Women and Socioeconomic Change in Twentieth Century Sweden.

Popular Abstract in Swedish Denna avhandling handlar om kvinnor och ekonomisk förändring i Sverige under 1900-talet. Den centrala frågeställningen är hur kvinnors förändrade utbildning och arbetsmarknadsdeltagande har påverkat och samvarierat med fertilitet över tid. Även om många idag anser Sverige vara ett jämställt land där män och kvinnor har lika möjligheter, fortsätter traditionella könsrollThis book deals with women and socioeconomic change in twentieth century Sweden. The main focus is on how women’s education and labor force participation have affected fertility over time. Although many perceive Sweden as a country where men and women have equal opportunities, traditional gender roles continue to constrain male and female activities and opportunities. The gender division of labor

Lexical structure and accenting in English and Swedish restricted texts

The issue of describing identity of sense relations that are used in contexts of anaphora to express contextually given information is discussed. In text-to-speech applictions, it is important to model given information, both linguistically and computationallly, since it is associated with tone accent patterns that differ from those on new information. The anlysis is illustrated using restricted t

Spin relaxation dynamics of quasiclassical electrons in ballistic quantum dots with strong spin-orbit coupling

We performed path integral simulations of spin evolution controlled by the Rashba spin-orbit interaction in the semiclassical regime for chaotic and regular quantum dots. The spin polarization dynamics have been found to be strikingly different from the D'yakonov-Perel' (DP) spin relaxation in bulk systems. Also an important distinction has been found between long time spin evolutions in classical

The dasyscyphins A similar to C and niveulone, new biologically active compounds from the ascomycete Dasyscyphus niveus

In the course of a screening for cytotoxic Compounds from fungi four new terpenoid metabolites, named dasyscyphins A, B, C, and niveulone were isolated from fermentations of Dasyscyphus niveus strain A0101. While dasyscyphin A (1) exhibited no significant biological activities in our test systems dasyscyphin B (2) and dasyscyphin C (3) showed cytotoxic activities against human (HepG2, Hela S3, U93