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Global Consensus Recommendations on Improving the Safety of Chronic Total Occlusion Interventions

Safety is of critical importance to chronic total occlusion (CTO) percutaneous coronary intervention (PCI). This global consensus statement provides guidance on how to optimise the safety of CTO) PCI, addressing the following 12 areas: 1. Set-up for safe CTO PCI; 2. Guide catheter-–associated vessel injuries; 3. Hydraulic dissection, extraplaque haematoma expansion, and aortic dissections; 4. Haem

Machining of Compacted Graphite Iron : A review

Compacted Graphite Iron (CGI) represents a unique combination of the characteristics of grey and spheroidal cast irons, sparking significant interest over the past two decades, particularly as a favoured material in several automotive industry applications, including engine components and heavy-duty vehicle parts. Despite its growing prominence, the full potential of CGI remains underutilised, pri

Role of land-ocean interactions in stepwise Northern Hemisphere Glaciation

The investigation of triggers causing the onset and intensification of Northern Hemisphere Glaciation (NHG) during the late Pliocene is essential for understanding the global climate system, with important implications for projecting future climate changes. Despite their critical roles in the global climate system, influences of land-ocean interactions on high-latitude ice sheets remain largely un

VR-assisted aggression treatment in forensic psychiatry : a qualitative study in patients with severe mental disorders

Introduction: Improvements in virtual reality (VR) have made it possible to create realistic, virtual settings for behavioral assessment and skills training that cannot otherwise be accessed in a safe way in forensic psychiatric settings. VR interventions are under development but little is known how forensic psychiatric patients with severe mental disorders experience VR-assisted assessments or t

Discovery of a dormant 33 solar-mass black hole in pre-release Gaia astrometry

Context. Gravitational waves from black-hole (BH) merging events have revealed a population of extra-galactic BHs residing in short-period binaries with masses that are higher than expected based on most stellar evolution models-And also higher than known stellar-origin black holes in our Galaxy. It has been proposed that those high-mass BHs are the remnants of massive metal-poor stars. Aims. Gaia

Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of clinical symptoms. Analysis of brain atrophy patterns using structural MRI and multivariate data analysis are an effective tool in identifying patients with subjective cognitive decline (SCD) at higher risk of progression to AD dementia. Atrophy patter

Relative decline in density of Northern Hemisphere tree species in warm and arid regions of their climate niches

Although climate change is expected to drive tree species toward colder and wetter regions of their distribution, broadscale empirical evidence is lacking. One possibility is that past and present human activities in forests obscure or alter the effects of climate. Here, using data from more than two million monitored trees from 73 widely distributed species, we quantify changes in tree species de

Prevalence of diabetes and hospitalization due to poor glycemic control in people with bladder cancer or renal cell carcinoma in Sweden

Background: Bladder cancer (BC) and Renal cell carcinoma (RCC) are the most common urogenital cancers among both sexes, with a yearly global incidence of around 500 000 each. Both BC and RCC have been linked to diabetes. Poor glycemic control (malglycemia) is a serious consequence of diabetes and a possible consequence of systemic treatments used in BC and RCC. The objective of this study was to i

Amniotic fluid derived mesenchymal stem cells reduce inflammation and improve lung function following transplantation in a porcine model

BACKGROUND: Lung transplantation is hindered by low donor lung utilization rates. Infectious complications are reasons to decline donor grafts due to fear of post-transplant primary graft dysfunction. Mesenchymal stem cells are a promising therapy currently investigated in treating lung injury. Full-term amniotic fluid-derived lung-specific mesenchymal stem cell treatment may regenerate damaged lu

The body says it all: non verbal indicators of choice-awareness

Recent work in cognitive science argues for the illusory nature of conscious will and considers occasional “blindness” to manipulations as indicative of our lack of awareness in choice making (e.g., Dennett, 1996; Johansson et al., 2013; Wegner, 2018). This claim is based upon the tendency of experimental participants not to detect such manipulations, and the similarity between verbal justificatio

Wounded and a Little Bit Monitored: An Ethnographic Study of Psychological Help in the Belarussian Refugee Community in Lithuania

This is an ethnographic study of psychological help for the refugees within the Belarusian refugee community in Lithuania. The paper approaches this phenomenon with attention to various cultural, political, and social factors that influenced how psychological discourse was mobilized and how the notion of psychological care was experienced, practiced, and resisted. The main argument of this study

Living with the threat of losing a child : Parents' experiences of the transplantation process with a severely ill child who received stem cells from a sibling

Purpose: When a child needs a hematopoietic stem cell transplant, the seriousness of the child's illness is highlighted. The purpose of this study was to explore parents' experiences of the transplantation process when two children in the family are involved, one severely ill child as the recipient and the other as the donor. Methods: In this qualitative study, interviews were conducted with 18 pa

Loss of Chromosome Y in Neuroblastoma Is Associated With High-Risk Disease, 11q-Deletion, and Telomere Maintenance

Neuroblastoma (NB) is a heterogeneous childhood cancer with a slightly higher incidence in boys than girls, with the reason for this gender disparity unknown. Given the growing evidence for the involvement of loss of the Y chromosome (LoY) in male diseases including cancer, we investigated Y chromosome status in NB. Male NB tumor samples from a Swedish cohort, analyzed using Cytoscan HD SNP-microa

L1 Swedish prominent syllable perception in Japanese words

This thesis investigates the perception of prominent syllables in Japanese words by native Swedish speakers. The study explores factors such as word type, pitch placement, and sentence structure that influence L1 Swedish speakers' accuracy in identifying the prominent syllable in Japanese words. The study also highlights the influence of linguistic context and individual variation on the perce

Related in Death? Further Insights on the Curious Case of Bishop Peder Winstrup and His Grandchild’s Burial

In 2021, we published the results of genomic analyses carried out on the famous bishop of Lund, Peder Winstrup, and the mummified remains of a 5–6-month-old fetus discovered in the same burial. We concluded that the two individuals were second-degree relatives and explored the genealogy of Peder Winstrup to further understand the possible relation between them. Through this analysis, we found that