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Understanding inhomogeneous MT (ihMT) in multi-parameter mapping of human brain: Towards larger ihMT, higher resolution, and influence of T1d

Inhomogenous Magnetization Transfer (ihMT), the differential response to irradiation at single and dual frequency offsets, is more complex than MT approaches. Expressing ihMT in terms of MT-saturation (ihMTsat) is a first step to quantification as it corrects for underlying T and B . Larger ihMTsat was observed for smaller frequency offsets, which is explained using MTsat as proxy for bound pool s

Mapping the architecture of the temporal artery with photoacoustic imaging for diagnosing giant cell arteritis

Photoacoustic (PA) imaging is rapidly emerging as a promising clinical diagnostic tool. One of the main applications of PA imaging is to image vascular networks in humans. This relies on the signal obtained from oxygenated and deoxygenated hemoglobin, which limits imaging of the vessel wall itself. Giant cell arteritis (GCA) is a treatable, but potentially sight- and life-threatening disease, in w

The present is a knife’s edge : St. Augustine’s philosophical presentism and the politics of expectation

The ways in which expectations for the future shape how actors and organizations make sense of the present has received growing interest and attention among science and technology scholars – with particular attention being paid to the role of expectations and prediction making in technology and finance. Nevertheless, while the imaginaries involved in the futures described by tech-entrepreneurs and

Sequence of flexion contracture development in the lower limb : a longitudinal analysis of 1,071 children with cerebral palsy

Background: To prevent severe contractures and their impact on adjacent joints in children with cerebral palsy (CP), it is crucial to treat the reduced range of motion early and to understand the order by which contractures appear. The aim of this study was to determine how a hip–knee or ankle contracture are associated with the time to and sequence of contracture development in adjacent joints. M

Heart age estimated using explainable advanced electrocardiography

Electrocardiographic (ECG) Heart Age conveying cardiovascular risk has been estimated by both Bayesian and artificial intelligence approaches. We hypothesised that explainable measures from the 10-s 12-lead ECG could successfully predict Bayesian 5-min ECG Heart Age. Advanced analysis was performed on ECGs from healthy subjects and patients with cardiovascular risk or proven heart disease. Regress

Shorter reproductive life span is associated with increased cardiovascular risk and total mortality in Swedish women from an observational, population-based study

Objectives: Reproductive history of women is of importance to estimate cardiovascular disease (CVD) risk. One aspect of that history is the reproductive life span (RLS), the period between onset of menarche and menopause. Previous studies have indicated an increased risk associated with shorter RLS, but this has never previously been tested in Scandinavian women. Our aim was to investigate such as

Laser excitation effects in lifetime-based high-speed phosphor thermometry

With high-speed phosphor thermometry becoming more established follows the need for an improved understanding of laser excitation induced measurement errors. With this aim in mind, the impact of kHz laser excitation on the lifetime method was investigated for the phosphors Mg3FGeO6:Mn (MFG) and YVO4:Tm. The results showed that significant measurement errors can occur for both phosphors. The Maximu

Seismic reflectivity, fracturing and stress field data from the FFC-1 exploratory geothermal project in SW Skåne, Sweden

Enhanced geothermal systems (EGS) are a potential heat source in many parts of the world, even in locations where the temperature gradient is relatively low. We present here an integrated study of reflection seismic data, borehole logs and seismicity analysis performed in conjunction with a geothermal exploratory project operated by E.ON in Malmö, Sweden. In 2020, the pre-existing 2.1 km deep FFC-