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A fault handling process for faults in district heating customer installations
Faults in district heating (DH) customer installations cause high return temperatures, which have a negative impact on both current and future district heating systems. Thus, there is a need to detect and correct these faults soon after they occur to minimize their impact on the system. This paper, therefore, suggests a fault handling process for the detection and elimination of faults in DH custo
Load Reduction for Timely Applications in the Cloud
In many IoT applications, sensor data is sent remotely to be processed, but only the freshest result is of interest. In this paper we investigate a feedback mechanism that aborts the processing of stale data at the remote end to reduce the load and save costs. The process is approximated by an M/M/$\infty$ queueing system with a feedback loop. We find the exact expression of the average computatioIn many IoT applications, sensor data is sent remotely to be processed, but only the freshest result is of interest. In this paper we investigate a feedback mechanism that aborts the processing of stale data at the remote end to reduce the load and save costs. The process is approximated by an M/M/∞ queueing system with a feedback loop. We find the exact expression of the average computational tim
Age-specific seasonal influenza vaccine effectiveness against different influenza subtypes in the hospitalized population in lithuania during the 2015–2019 influenza seasons
Background: Continuous monitoring of seasonal influenza vaccine effectiveness (SIVE) is needed due to the changing nature of influenza viruses and it supports the decision on the annual update of vaccine composition. Age-specific SIVE was evaluated against different influenza sub-types in the hospitalized population in Lithuania during four influenza seasons. Methods: A test-negative case-control
3d foot reconstruction based on mobile phone photographing
Foot measurement is necessary for personalized customization. Nowadays, people usually obtain their foot size by using a ruler or foot scanner. However, there are some disadvantages to this, namely, large measurement error and variance when using rulers, and high price and poor convenience when using a foot scanner. To tackle these problems, we obtain foot parameters by 3D foot reconstruction base
ApoE and ApoE Nascent-Like HDL Particles at Model Cellular Membranes : Effect of Protein Isoform and Membrane Composition
Apolipoprotein E (ApoE), an important mediator of lipid transportation in plasma and the nervous system, plays a large role in diseases such as atherosclerosis and Alzheimer's. The major allele variants ApoE3 and ApoE4 differ only by one amino acid. However, this difference has major consequences for the physiological behaviour of each variant. In this paper, we follow (i) the initial interaction
Reinforced versus standard stapler transection on postoperative pancreatic fistula in distal pancreatectomy : multicentre randomized clinical trial
BACKGROUND: Postoperative pancreatic fistula is the leading cause of morbidity after distal pancreatectomy. Strategies investigated to reduce the incidence have been disappointing. Recent data showed a reduction in postoperative pancreatic fistula with the use of synthetic mesh reinforcement of the staple line. METHODS: An RCT was conducted between May 2014 and February 2016 at four tertiary refer
Increased Above- and Belowground Plant Input Can Both Trigger Microbial Nitrogen Mining in Subarctic Tundra Soils
Flowrider: Fast On-Demand Key Provisioning for Cloud Networks
Increasingly fine-grained cloud billing creates incentives to review the software execution footprint in virtual environments. For example, virtual execution environments move towards lower overhead: from virtual machines to containers, unikernels, and serverless cloud computing. However, the execution footprint of security components in virtualized environments has either remained the same or eve
Physical activity patterns, adherence to using a wearable activity tracker during a 12-week period and correlation between self-reported function and physical activity in working age individuals with hip and/or knee osteoarthritis
Background: A majority of individuals with osteoarthritis (OA) are insufficiently physically active. Self-monitoring with wearable activity trackers (WAT) could promote physical activity (PA), and increased knowledge of PA patterns and adherence to using a WAT is needed. The aim of this study was to describe PA patterns and adherence to WAT-use during an intervention among participants of working
Sustainability as a Real Utopia – Heuristics for transformative sustainability research
The idea of ‘Sustainability as a Real Utopia’ elaborated on here adapts sociologist Erik Olin Wright’s emancipatory social science and is a heuristic informed by critical realism and social theory for interdisciplinary research on viable alternatives that move society towards achieving sustainability. Starting from the proposition that many environmental problems are rooted in how social structure
Multimodal Assessment of Vascular and Ventricular Function in Children and Adults With Bicuspid Aortic Valve Disease
Background: Bicuspid aortic valve (BAV), the most common congenital cardiac anomaly, has been associated with an aortopathy, increased aortic stiffness and diastolic dysfunction. The involved mechanisms and impact of age remain unclear. It was the aim of this study to characterize arterial and cardiac function, their correlation, and the effect of age in children and adults with a history of BAV.
Routine Oxygen Therapy Does Not Improve Health-Related Quality of Life in Patients With Acute Myocardial Infarction—Insights From the Randomized DETO2X-AMI Trial
Background: After decades of ubiquitous oxygen therapy in all patients with acute myocardial infarction (MI), recent guidelines are more restrictive based on lack of efficacy in contemporary trials evaluating hard clinical outcomes in patients without hypoxemia at baseline. However, no evidence regarding treatment effects on health-related quality of life (HRQoL) exists. In this study, we investig
The human anti-CD40 agonist antibody mitazalimab (ADC-1013; JNJ-64457107) activates antigen-presenting cells, improves expansion of antigen-specific T cells, and enhances anti-tumor efficacy of a model cancer vaccine in vivo
Non-responders to checkpoint inhibitors generally have low tumor T cell infiltration and could benefit from immunotherapy that activates dendritic cells, with priming of tumor-reactive T cells as a result. Such therapies may be augmented by providing tumor antigen in the form of cancer vaccines. Our aim was to study the effects of mitazalimab (ADC-1013; JNJ-64457107), a human anti-CD40 agonist IgG
Trust in government in Sweden and Denmark during the COVID-19 epidemic
Did the different public-health policies that Sweden and Denmark pursued in the beginning of the COVID-19 pandemic result in different levels of public trust in governments’ and health authorities’ ability to guide the two countries safely through the pandemic? How did the level of trust change as the pandemic unfolded? And were there any cross-country differences in the correlates of trust? Using
On the Uniqueness Problem for Quadrature Domains
We study questions of existence and uniqueness of quadrature domains using computational tools from real algebraic geometry. These problems are transformed into questions about the number of solutions to an associated real semi-algebraic system, which is analyzed using the method of real comprehensive triangular decomposition.
Ett rum för de ostyrigaste och bullersammaste - eller: Var låg proban? : Del 2
Den andra av två artiklar rörande det fängelse, den s k proban, som Lunds universitet hade under den tid lärosätet ägde egen jurisdiktion över anställda och studenter. Denna andra del behandlar studentoroligheter under tidigt 1800-tal, den oklara frågan var proban var placerad under 1800-talet samt några av de sista studenterna att spärras in häri under 1830- och 1840-talen, dels för brott, dels s
“True Religion” and Hume’s Practical Atheism
The argument and discussion in this paper begins from the premise that Hume was an atheist who denied the religious or theist hypothesis. However, even if it is agreed that that Hume was an atheist this does not tell us where he stood on the question concerning the value of religion. Some atheists, such as Spinoza, have argued that society needs to maintain and preserve a form of “true religion”,
Exploring physiological stability of infants in Kangaroo Mother Care position versus placed in transport incubator during neonatal ground ambulance transport in Sweden
Background: The positive effects of Kangaroo mother care in NICU’s are well documented but, to a lesser extent, explored during inter-hospital neonatal transport. Inter-hospital transport, with the infant placed in a transport incubator, increases the risk of separation while infants in Kangaroo mother care position implies that the parents accompany the transport. There exists limited knowledge i
Millimeter-Wave Vertical III-V Nanowire MOSFET Device-To-Circuit Co-Design
Vertical III-V nanowire MOSFETs show potential towards the ultimate transistor scaling. A high transconductance and current density are achieved based on the gate-all-around architecture. This work presents a high-frequency design of such devices, achieving more than 600 GHz cut-off frequencies (fT, fmax), at 20 nm gate length. Furthermore, capacitance design and scaling trends, supported by COMSO