Search results
Filter
Filetype
Your search for "*" yielded 534488 hits
Good life in old age : Qualitative interviews about ageing with older adults with mild intellectual disability, prior to an educational intervention
Background: Knowledge about ageing from the perspective of people with intellectual disability is extremely scarce, which means a lack of evidence-based interventions for healthy ageing adjusted to their needs. Aim: To investigate how people with intellectual disability experience ageing, prior to an educational intervention. Methods: Twenty-six persons with mild intellectual disability, age 42-7
Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome : a pooled analysis of four observational studies
Background: Geoeconomic variations in epidemiology, the practice of ventilation, and outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data of four large observational studies. Methods: In this pooled analysis we harmonised individual patien
Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data : an observational, multicohort, retrospective analysis
Background: Two acute respiratory distress syndrome (ARDS) subphenotypes (hyperinflammatory and hypoinflammatory) with distinct clinical and biological features and differential treatment responses have been identified using latent class analysis (LCA) in seven individual cohorts. To facilitate bedside identification of subphenotypes, clinical classifier models using readily available clinical var
Tre mäktiga kvinnor i blixtbelysning
A story of promising regime of concurrent Electro-Enhanced Chemo Radiation Immune Tumour-therapy
AbstraktSyftet med den här berättelsen handlar om Abskopal regression av subkutant implanterat N29 råttgliom som inträffar efter immunisering med syngena IFN-utsöndrande celler och behandling av kontralaterala tumörer med pulserande elektriska fält (PEF) och/eller strålbehandling (RT). Studien utfördes på råttor av Fischer-344-stammen med råttgliom N29-tumörer implanterade subkutant på flanken el
Label-FreeHigh-ResolutionPhotothermalOpticalInfraredSpectroscopyfor Spatiotemporal Chemica lAnalysis in Fresh, Hydrated Living Tissues and Embryos
Label-free chemical imaging of living and functioning systems is the holy grail of biochemical research. However, existing techniques often require extensive sample preparation to remove interfering molecules such as water, rendering many molecular imaging techniques unsuitable for in situ structural studies. Here, we examined freshly extracted tissue biopsies and living small vertebrates at submi
Bioactive Suture with Added Innate Defense Functionality for the Reduction of Bacterial Infection and Inflammation
Surgical site infections (SSI) are a clinical and economic burden. Suture-associated SSI may develop when bacteria colonize the suture surface and form biofilms that are resistant to antibiotics. Thrombin-derived C-terminal peptide (TCP)-25 is a host defense peptide with a unique dual mode of action that can target both bacteria and the excessive inflammation induced by bacterial products. The pep
Online remote behavioural intervention for tics in 9- to 17-year-olds : the ORBIT RCT with embedded process and economic evaluation
BACKGROUND: Behavioural therapy for tics is difficult to access, and little is known about its effectiveness when delivered online.OBJECTIVE: To investigate the clinical and cost-effectiveness of an online-delivered, therapist- and parent-supported therapy for young people with tic disorders.DESIGN: Single-blind, parallel-group, randomised controlled trial, with 3-month (primary end point) and 6-m
How accessibility to schools is not (just) a transport problem: the case of public school choice in the city of Malmö, Sweden
There is currently a lack of studies exploring how transport investments and school admission policies in a city can affect the distribution of accessibility to schools. The aim of this study is to investigate if, for whom, and the ways in which, accessibility to schools can change following (1) a change to the city’s public school admission policy and (2) investments in public transport infrastru
Hur sannolikt är troligt? Ett entreprenadrättsligt fall ur ett rättsekonomiskt perspektiv
Optically pure lactic acid production from lignocellulosic biomass
Lactic acid is a platform chemical that can be used for many applications. More recently, optically pure lactic acid—L- or D-lactic acid enantiomers—have been used for the polymerisation to poly-lactic acid (PLA). The possibility of tailoring the properties of this bioplastic by adjusting the ratio of each enantiomer might help to accelerate the substitution of petroleum-based plastics with bio-ba
Early Initiation of Breastfeeding and Associated Factors Among Women of Reproductive age in Simiyu Region, Tanzania
BACKGROUND: Breast milk provides infants with complete nutrition for immune development and protection against childhood diseases and associated mortality. Early initiation of breastfeeding (EIBF) aids in providing colostrum to newborns, providing protection against infection, and improving newborn and infant survival. Although Simiyu reported the lowest prevalence of EIBF in Tanzania, no study ha
Sustainability Science: Managing Risk and Resilience for Sustainable Development
Continues to fill gaps between the descriptive, conceptual, and transformative sustainability science.Sustainability is increasingly important across functional sectors and scientific disciplines. Policy-makers, practitioners, and academics continue to wrestle with the complexity of risk, resilience, and sustainability, but because of the necessary transdisciplinary focus, it is difficult to find
Between Belief and Disbelief, Between Religion and Secularity : Introducing Non-Doxasticism and Semi-Secularity in Worldview Education
In order to include all outlooks and perspectives on the world prevalent in contemporary society, countries like Sweden have replaced traditional religious education with worldview education. However, current worldview theory fails to make justice to two important facts concerning the contemporary religious landscape. Firstly, a great many people are semi-secular rather than traditional believers
Photoredox Catalysis Driven by Visible Light and Iron N-Heterocyclic Carbene Complexes
Photoredox catalysis is a rapidly expanding field, in which organic transformations are catalysed using light. The most commonly used photoredox catalysts (PCs) are transition metal complexes which absorb in the visible region of the electromagnetic spectrum. Traditionally, such PCs are based on scarce and expensive metals, such as ruthenium or iridium, in combination with polypyridyl ligands. Res
Taking Environmental Rights in the Anthropocene Seriously : The Case of Biodiversity and the Nagoya Protocol
Anterior cingulate sulcation is associated with onset and survival in frontotemporal dementia
Frontotemporal dementia is the second most common form of early onset dementia ( 0.41, P = 0.02. Education was not associated with age at onset (β = -0.05, P = 0.75). The presence of a right paracingulate sulcus was associated with an 83% increased risk of death per year after age at onset (hazard ratio 1.83, confidence interval [1.09-3.07], P < 0.02), whilst the mean age at death was similar for
A 3D model for detecting and communicating the archaeological risk
Early life influences on adult organ function, health and disease, including data from Swedish population-based cohorts
Prenatal insults or adverse events during the in-utero period may lead to suboptimal function of adult organs because of the impairment of critical organ development and growth, as linked to lower birth weight. This may ultimately predispose the individual to the later onset of some diseases in adulthood, a process known as Developmental Origins of Health and Disease (DOHaD). There is ample eviden