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Physical impairments in longstanding hip and groin pain : Cross-sectional comparison of patients with hip-related pain or non-hip-related groin pain and healthy controls

Objectives: To compare physical impairments between patients with hip-related pain and those with non-hip-related groin pain, and to compare both patient groups with healthy controls. Design: Cross-sectional. Participants: Eighty-one hip and groin pain patients were consecutively included and categorized into having hip-related pain or non-hip-related groin pain. Twenty-eight healthy controls were

The contributions of public health policies and healthcare quality to gender gap and country differences in life expectancy in the UK

Background: In many high-income countries, life expectancy (LE) has increased, with women outliving men. This gender gap in LE (GGLE) has been explained with biological factors, healthy behaviours, health status, and sociodemographic characteristics, but little attention has been paid to the role of public health policies that include/affect these factors. This study aimed to assess the contributi

Photodissociation dynamics of halogenated aromatic molecules : The case of core-ionized tetrabromothiophene

We studied the gas-phase photodissociation of a fully halogenated aromatic molecule, tetrabromothiophene, upon core-shell ionization by using synchrotron radiation and energy-resolved multiparticle coincidence spectroscopy. Photodynamics was initiated by the selective soft X-ray ionization of three elements-C, S, and Br-leading to the formation of dicationic states by Auger decay. From a detailed

The Contribution of Iron Oxides to theWet-Rail Phenomenon

This paper reviews the current literature regarding iron oxide formation in the wheel-rail contact in order to assess the possible role of iron oxides in the “Wet-Rail” phenomenon, which causes low adhesion between the wheel and the rail. The paper discusses the structure and formation of oxides from a chemical perspective before analysing the direct tribological effects and outlining the techniqu

Human complex-forming glycoprotein, heterogeneous in charge : the primary structure around the cysteine residues and characterization of a disulfide bridge

The amino acid sequence of the cysteine-containing regions of human complex-forming glycoprotein, heterogeneous in charge (protein HC) was determined by studies of the tryptic peptides of the completely reduced and radioalkylated protein. One of the cysteines was located in the amino-terminal part of the molecule at position 34....Diagonal map electrophoresis showed that the cysteine residue in th

Next-Generation Gene Therapy for Parkinson's Disease Using Engineered Viral Vectors

Recent technological and conceptual advances have resulted in a plethora of exciting novel engineered adeno associated viral (AAV) vector variants. They all have unique characteristics and abilities. This review summarizes the development and their potential in treating Parkinson's disease (PD). Clinical trials in PD have shown over the last decade that AAV is a safe and suitable vector for gene t

Choice of dialysis modality among patients initiating dialysis : results of the Peridialysis study

Background: In patients with end-stage kidney disease (ESKD), home dialysis offers socio-economic and health benefits compared with in-centre dialysis but is generally underutilized. We hypothesized that the pre-dialysis course and institutional factors affect the choice of dialysis modality after dialysis initiation (DI).Methods: The Peridialysis study is a multinational, multicentre prospective

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In Burkina Faso, the recent emergence of the “koglweogo” vigilante groups is often explained as a result of a “security vacuum.” This explanation, however, tends to depoliticize the power relations that underlie the phenomenon of vigilantism. In this article we analyze the justifications for the emergence and work of koglweogo groups and for the national policy of community-based policing that aim

Ombordmätningar av luftburna partiklar i X60 samt på citybanans plattformar

SyfteMålsättningen med denna studie var dels att säkerställa att tågpersonalen inte utsätts för höga halter av partiklar i sitt arbete på X60B fordon som trafikerar Arlanda. Syftet var även att ta fram ett förhållande mellan partikelnivåerna i tunnelmiljö och ombord på pendeltågsfordon av typ X60B i förarhytterna för att avgöra ventilationsfiltrets kapacitet. Kunskapen om filtreringseffektiviteten

Contributions to Molecular Phylogeny of Lichen-Forming Fungi 2. Review of Current Monophyletic Branches of the Family Physciaceae

Seven genera new to science, i.e.: Helmutiopsis, Huriopsis, Johnsheardia, Klauskalbia, Kudratovia, Kurokawia and Poeltonia of the Physciaceae are proposed for the ‘Rinodina’ atrocinerea, the ‘Rinodina’ xanthophaea, the ‘Rinodina’ cinnamomea, the ‘Heterodermia’ obscurata, the ‘Rinodina’ straussii, the ‘Anaptychia’ isidiata and the ‘Physconia’ grisea groups consequently that all form strongly suppor

CDG-Id in two siblings with partially different phenotypes

We present two sibs with congenital disorder of glycosylation (CDG) type Id. Each shows severe global delay, failure to thrive, seizures, microcephaly, axial hypotonia, and disaccharidase deficiency. One sib has more severe digestive issues, while the other is more neurologically impaired. Each is compound heterozygous for a novel point mutation and an already known mutation in the ALG3 gene that

Trajectories of body mass index and risk for coronary heart disease : A 38-year follow-up study

Objective Obesity is a well-known risk factor for coronary heart disease (CHD), but there is little evidence on the effect of long-term trajectories of body mass index (BMI) over the life course. By using repeated assessments, the aim was to study the risk of CHD in adults during 38 years in different trajectories of BMI. Methods A sample of 2129 men and women, aged 20-59 years at baseline, took p

De novo DHDDS variants cause a neurodevelopmental and neurodegenerative disorder with myoclonus

Subcellular membrane systems are highly enriched in dolichol, whose role in organelle homeostasis and endosomal-lysosomal pathway remains largely unclear besides being involved in protein glycosylation. DHDDS encodes for the catalytic subunit (DHDDS) of the enzyme cis-prenyltransferase (cis-PTase), involved in dolichol biosynthesis and dolichol-dependent protein glycosylation in the endoplasmic re