The gut microbiota plays a crucial role in health and is significantly modulated by human diets. In addition to Western diets which are rich in proteins, high-protein diets are used for specific populations or indications, mainly weight loss. In this study, we investigated the effect of protein supplementation on Bacteroides caccae, a Gram-negative gut symbiont. The supplementation with whey prote

Background: Optimal anticoagulation management in patients with myeloproliferative neoplasms (MPN) experiencing splanchnic vein thrombosis (SpVT) requires balancing risks of bleeding and recurrent thrombosis. Objectives: We conducted a systematic review and meta-analysis to assess the incidence of bleeding and thrombosis recurrence in patients with MPN-SpVT. Methods: We included retrospective or p

Antibiotic resistance is a growing global concern, with many ecological niches showing a high abundance of antibiotic resistance genes (ARGs), including the human gut. With increasing indications of ARGs in infants, this study aims to investigate the gut resistome profile during early life at a wider geographic level. To achieve this objective, we utilized stool samples data from 26 studies involv

Chromosomal aneuploidy, that is, numerical chromosome aberrations, is one of the molecular hallmarks of cancer. However, when neoplasms are studied with sequencing- and array-based approaches, chromosome numbers and ploidy states are typically inferred from bulk DNA data. Furthermore, published molecular estimates of neoplasia-associated aneuploidy often also include genomic imbalances resulting f

The gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, we used high-resolution shotgun metagenomics and targeted metabolomic analysis to characterize influenza-associated changes in the composition and metabolism of the mouse gut microbiota. We observed several taxonomic-level changes on day (D)7 post-infection, including

The TFM-DYN model represents a significant advancement from static flow accumulation estimations into dynamic hydrological modeling (Nilsson et al., 2021). It incorporates variable precipitation in time and space as input together with high-resolution topography and includes functions for friction and infiltration to produce results such as water depths, flow velocity, inundated areas, flow pathwa

In 2023, the first edition of the diachronic-contemporary Swedish AcademyDictionary (SAOB) was finished after more than 130 years of work. The dictionary contains over 500,000 entries and describes the Swedish language from the 1520s to the present day. However, a consequence of the extended time of publication is that a significant part of the content, in particular in the first volumes, was out In 2023, the first edition of the diachronic-contemporary Swedish Academy Dictionary (SAOB) was finished after more than 130 years of work. The dictionary contains over 500,000 entries and describes the Swedish language from the 1520s to the present day. However, a consequence of the extended time of publication is that a significant part of the content, in particular in the first volumes, was out

Direct oral anticoagulants (DOAC) are increasingly common, with bleeding events associated with elevated plasma concentrations. Rotational thromboelastometry (ROTEM), a point-of-care tool for assessing secondary hemostasis, has demonstrated a correlation with increasing concentrations of DOAC. However, previous studies have only partially explored this relationship. The primary aim in the current

Bakgrund: HLR innebär att hjärtkompressioner och inblåsningar ska göras i händelse av ett plötsligt hjärtstopp. En legitimerad läkare får, i samråd med annan legitimerad personal, fatta beslut om att avstå HLR. Att genomföra utsiktslös HLR vid svår kronisk sjukdom, eller vid livets slut, kan leda till förlängt lidande och förlust av värdighet för patienten. Att genomföra utsiktslös HLR kan även le

Bakgrund: Äldres population ökar globalt och behovet av akutsjukvård är större hos den äldre befolkningen än populationen i övrigt. Våld mot äldre kan vara svårt att upptäcka och kan leda till stora konsekvenser för den äldre. Akutsjukvården har en betydelsefull roll i att identifiera äldre våldsutsatta personer. Syfte: Beskrivning av hur våld i nära relation mot äldre kan identifieras inom akutsj

Introduction: Although antiretroviral therapy (ART) leads to reduced tuberculosis (TB) incidence in people with HIV (PWH), ART recipients remain at higher risk of TB compared to HIV-seronegative people. With accelerated ART rollout in sub-Saharan Africa, increasing proportions of TB cases among PWH in people receiving long-term ART have been reported. Objective: To determine TB notifications among

We investigate whether number of episodes (NoEs) meaningfully reflect genetic risk and genetic heterogeneity for five primary disorders—Drug Use Disorder (DUD), Alcohol Use Disorder (AUD), Major Depression (MD), Bipolar Disorder (BD), and Schizophrenia (SZ) ascertained from Swedish population registries. We utilize Genetic Risk Ratios (GRR)—defined as the ratio of the genetic risk for secondary di

Significant groundwater (GW) head decline due to excessive withdrawal is an essential hydrological concern in several major plains of Iran. The capacity of an aquifer to retain GW can be described through the storativity parameters. Traditional methods to define these parameters are costly, time-consuming, and sometimes ineffective. The storativity of an aquifer, irrespective of its confinement ty

The Cretaceous period is the time of the first appearance of the diatoms in the fossil record. These fossils give us direct evidence of the age and early evolution of the diatom lineage. The fossil record, however, is incomplete and therefore often extrapolated through time-calibrated phylogenies. These two approaches offer different perspectives on the early evolution of diatoms, which is still p

Volunteers participating in medical research must be adequately protected. A volunteer can be a person undergoing treatment for an illness (a patient) or a healthy person. The radiological imaging and therapy procedures used could be routine or project-specific with different purposes. This contribution aims to explore the features and conditions of this planned exposure situation and to address s

Hanna Poddig interviewed by Sophia New. As part of the research week at the HZT-Inter-University Centre for Dance Berlin we were looking into different practices and contexts in which bodies turn into shields, either by choice or by force. The following conversation explores Hanna's experience as eco-activist and the body- based strategies that she shared during the workshop.

Schlieren imaging has been established as a reliable optical measurement technique for flame visualizations and retrieval of laminar burning velocity information. However, it is off limited capability and adaptability due to the optical configuration of a conventional Schlieren setup. In this regard, background oriented Schlieren (BOS) provides a unique opportunity to quantitatively characterize d

Many forms of bioimage analysis involve the detection of objects and their outlines. In the context of microscopy-based high-throughput drug and genomic screening and even in smaller scale microscopy experiments, the objects that most often need to be detected are cells. In order to develop and benchmark algorithms and neural networks that can perform this task, high-quality datasets with annotate