Given an undirected graph and two pairs of vertices (si, ti) for i ϵ{ 1, 2} we show that there is a polynomial time Monte Carlo algorithm that finds disjoint paths of smallest total length joining si and ti for i ϵ{1, 2}, respectively, or concludes that there most likely are no such paths at all. Our algorithm applies to both the vertex- and edge-disjoint versions of the problem. Our algorithm is

Objectives: Assess the relationship of cognitive impairment to disability, accounting for depression severity and frailty, among older adults with late-life depression (LLD). Methods: Data were analyzed from 78 community-dwelling older adults with LLD and without dementia (age M = 71.9; SD = 6.1). Cognitive functioning was assessed using a comprehensive neuropsychological battery. Depression sever

Background and aims Symptoms of dizziness and pain are both common complaints and the two symptoms often seem to coincide. When symptoms appear concomitant for sustained periods of time the symptoms might maintain and even exacerbate each other, sometimes leading to psychological distress. In order to evaluate such comorbidity we studied patients referred to a vestibular unit and to a psychiatric

Commodity prices and their secular trends are at the core of many different development theories, particularly relevant for the Latin American region, like the Prebisch-Singer hypothesis, the natural resource curse theory or the somehow malthusian scarcity prediction. In this article we review the international copper price indices available in the literature and we compare them with a new data se

Innovation productivity of expatriate researchers and human capital that empowers them is an important issue; however, with a scarcity of relevant data, formal empirical evidence has been limited. This paper uses a rich dataset of foreign researchers at a leading German research institution to study the drivers of their innovation productivity (measured by patents and invention disclosures). Anoth

Transcription factor (TF)-based reprogramming of somatic tissues holds great promise for regenerative medicine. Previously, we demonstrated that the TFs GATA2, GFI1B, and FOS convert mouse and human fibroblasts to hemogenic endothelial-like precursors that generate hematopoietic stem progenitor (HSPC)-like cells over time. This conversion is lacking in robustness both in yield and biological funct

The main current methods for controlling American Foulbrood (AFB) in honeybees, caused by the bacterial pathogen Paenibacillus larvae, are enforced incineration or prophylactic antibiotic treatment, neither of which is fully satisfactory. This has led to an increased interest in the natural relationships between the pathogenic and mutualistic microorganisms of the honeybee microbiome, in particula

Purpose: This study aims to clarify the mechanism of film hole location at the span-wise direction of an internal cooling channel with crescent ribs on the adiabatic film cooling performance, three configurations are designed to observe the effects of the distance between the center of the ellipse and the side wall(Case 1, l = w/2, Case 2, l = w/3 and for Case 3, l = w/4). Design/methodology/appro

We present the first study to examine the year-round distribution, activity patterns, and habitat use of one of New Zealand’s most common seabirds, the fluttering shearwater (Puffinus gavia). Seven adults from Burgess Island, in the Hauraki Gulf, and one individual from Long Island, in the Marlborough Sounds, were successfully tracked with combined light-saltwater immersion loggers for one to thre

Humoral immunity is important in limiting clinical disease in malaria, yet the longitudinal B cell response to infection remains unclear. We performed a 1-year prospective study in patients treated for acute Plasmodium falciparum malaria for the first time or with previous exposure to the disease. Using an unbiased exploratory approach with mass cytometry, followed by targeted flow cytometry, we f

The grand challenges of contemporary fundamental physics-dark matter, dark energy, vacuum energy, inflation and early universe cosmology, singularities and the hierarchy problem-all involve gravity as a key component. And of all gravitational phenomena, black holes stand out in their elegant simplicity, while harbouring some of the most remarkable predictions of General Relativity: event horizons,

Background: Roux-en-Y gastric bypass (RYGB) is an effective obesity treatment in adults and has become established in adolescents. Lower adherence to supplementation in adolescents confers a risk for long-term nutritional deficiencies. Objectives: To assess adherence to supplementation, micronutrient intake, and biochemistry in adolescents through 5 years after RYGB. Setting: University hospitals,

Den idag helt dominerande idén om den täta staden har en rad olika uttryck. Även i miljonprogramsområden får förtätningsprojekt olika effekt beroende på specifika omständigheter, inte minst hur förtätningar samverkar med andra större stadsomvandlingsprojekt—såsom storskaliga renoveringar av hyreshusbestånd och privatisering—och rent materiella utvecklingslinjer såsom ökad bostadsbrist, trångboddhe

Depression is a disabling condition, causing suffering worldwide. The purpose of this paper is to review studies that have used Intensive Longitudinal Data (ILD) in research on depression treatment. Intensive longitudinal data in the form of daily diaries, experience sampling method (ESM), and ecological momentary assessment (EMA) are increasingly used in psychotherapy research to gather individua

We evaluated a structured education- and exercise-based self-management program for patients with knee or hip osteoarthritis (OA), using a registry-based study of data from 44,634 patients taken from the Swedish “Better Management of Patients with Osteoarthritis” registry. Outcome measures included a numeric rating scale (NRS), EuroQol five dimension scale (EQ-5D), Arthritis self-efficacy scale (A

Goda kamrater, ett antal buteljer punsch, en droska, och en likkista av barnmodell – vad är det värsta som kan hända? I lundastudenten Carl Lindells fall slutade det riktigt illa, med både tidningsskriverier och rektorsförhör. Arkivarien vid universitetsarkivet Henrik Ullstad berättar historien om en Malmöutflykt på 1880-talet som tog en ände med förskräckelse.Good companions, numerous bottles of punsch, a carriage and a child-sized coffin – what could possibly go wrong? In the case of Lund student Carl Lindell, it all went horribly wrong, with stories in the newspapers and being taken before the vice-chancellor. University Library archivist, Henrik Ullstad, tells the story of a Malmö excursion in the 1880s that came to an alarming end.