Combined with concerns about climate change, air pollution and human health, the COVID-19 pandemic has renewed the use of and policy interest in active transport (AT) modes, namely cycling and walking. However, we note a high degree of uncertainty and lack of assessments addressing the economic benefits of AT policies; particularly when they are used as a mix of policies at the local level. This s

The aim of this report is to provide a detailed description of the eight development projects recommended for the first strategy period (2021-2023) of the project “A National Strategy for Standardisation of Digital Information Management within the Built Environment”. The report also contains a description of the vision and the objectives of the strategy. The project has been led by Pontus Bengtso

Background: Digital breast tomosynthesis (DBT) improves breast cancer (BC) detection compared to mammography, however, it is unknown whether this reduces interval cancer rate (ICR) at follow-up. Methods: Using individual participant data (IPD) from DBT screening studies (identified via periodic literature searches July 2016 to November 2019) we performed an IPD meta-analysis. We estimated ICR for

Background: Mutations in the CDH1 and the role of E-cadherin proteins are well established in gastric cancer. Several in silico tools are available to predict the pathogenicity of the mutations present in the genes with varying efficiency and sensitivity to detect the pathogenicity of the mutations. Objective: Our objective was to identify somatic pathogenic variants in CDH1 involved in Gastric Ca

Pathological nystagmus is a symptom of oculomotor disease where the eyes oscillate involuntarily. The underlying cause of the nystagmus and the characteristics of the oscillatory eye movements are patient specific. An important part of clinical assessment in nystagmus patients is therefore to characterise different recorded eye-tracking signals, i.e. waveforms. Approach. A method for characterisat

In this article I look at two hypothetical examples with the purpose of challenging some of the underlying intuitions that affect our views on immortality.

Prostate cancer bone metastasis is still not fully understood, and increased knowledge could aid in the development of better treatment options for patients in the future. This thesis focuses on microRNAs (miRNAs), which modulate gene expression in healthy and tumour cells. Using cell culture, animal and patient studies, we investigated the biological role of microRNA-96 (miR-96) and microRNA-379

Affective and anxiety diagnoses are common in older people with intellectual disability (ID). The aim was to describe support and social services for older people with ID and affective and/or anxiety diagnoses, also to investigate in this study group the association between support and social services and frailty factors in terms of specialist healthcare utilisation, multimorbidity, polypharmacy,

Acylation of 1D-myo-inositol 1,2,6-trisphosphate (α-trinositol) followed by alkylation of the phosphate groups with benzyl bromoacetate or 2-benzyloxyethyl iodide and deprotection provides a route to analogues with modified phosphate groups. The modifications made alter steric and ionisation properties but the possibility to participate in hydrogen bonding and ionic interaction is retained.

Despite the growing interest in employee voice, real opportunities for co-workers to challenge the status quo are limited (Kenny et al., 2020; Wilkinson et al., 2018; de Maria, 2008). This conceptual paper explores the unruly dimension of employee voice in connection to whistleblowing and protest as modes of ethical resistance (de Maria, 2008). It partly follows recent attempts inorganisation stud

Electrostatic interactions play crucial roles in protein function. Measuring pKa value perturbations upon complex formation or self-assembly of e.g. amyloid fibrils gives valuable information about the effect of electrostatic interactions in those processes. Site-specific pKa value determination by solution NMR spectroscopy is challenged by the high molecular weight of amyloid fibrils. Here we rep

Hvorfor skal den vigtige debat om Spotifys indflydelse på musiklytning og musikoplevelse ende som et ufrugtbart møde mellem et personangreb og en forsvarstale? Er Seismografs læsere mon blevet klogere på, hvad Spotifys digitale infrastruktur kan gøre ved brugerens lytteoplevelse? Streaming-forskeren Andreas Helles Pedersen hiver et tredje øre ind i debatten.

The ALICE Collaboration reports the first fully-corrected measurements of the N-subjettiness observable for track-based jets in heavy-ion collisions. This study is performed using data recorded in pp and Pb-Pb collisions at centre-of-mass energies of s = 7 TeV and sNN = 2.76 TeV, respectively. In particular the ratio of 2-subjettiness to 1-subjettiness, τ2/τ1, which is sensitive to the rate of two

Active matter exhibits various forms of nonequilibrium states in the absence of external forcing, including macroscopic steady-state currents. Such states are often too complex to be modeled from first principles, and our understanding of their physics relies heavily on minimal models. These are mostly studied in the case of "dry"active matter, where particle dynamics are dominated by friction wit