BACKGROUND AND AIMS: Although increasing evidence suggests involvement of the distal airway in all stages of asthma, it is not known whether structural changes (defined as airway remodelling) occur in the distal airways of subjects with mild asthma and those with atopy. The aim of this study was to compare control subjects and those with mild asthma in relation to fibroblast phenotypes and remodel

Introduction to the poetry of Italian writer Andrea Zanzotto

The radiative lifetimes of the states in the (n=5-8) 3snp P-1(1) sequence of neutral magnesium were investigated using time-resolved laser-induced fluorescence. Excitation from the 3s2 S-1(0), ground state was performed using VUV radiation, which was produced by resonant sum-difference frequency mixing in a krypton gas cell. We find tau(n=5): 54(3) ns, tau(n=6): 140(10) ns, tau(n=7): 290(20) ns, t

The global methylation profile and the mutational status of 633 specific epigenetic regulators were analyzed in the pediatric tumor clear cell sarcoma of the kidney (CCSK). Methylation array analyses of 30 CCSKs revealed CCSK tumor DNA to be globally hypermethylated compared to Wilms tumor, normal fetal kidney, and adult kidney. The aberrant methylation pattern of CCSKs was associated with activat

Objectives. To gain updated estimates of prevalence and incidence of RA and proportion on biological treatment in southern Sweden. Methods. Inpatient and outpatient health care provided to residents in the southernmost county of Sweden (1.2 million inhabitants) is registered in the Skåne Health Care Register (SHCR). We identified residents aged >/=20 years who had received a diagnosis of RA at lea

Popular Abstract in English In the past decade, mobile wireless communication have had a tremendous impact on the way people perceive and use mobile devices, most popularly the mobile phone. Apart from making phone calls, they are capable of being cameras to take pictures and videos, able to browse the Internet, do video calling and much more just like an yesteryear computer. The wireless medium iThe demand for spectrum resources in cellular systems worldwide has seen a tremendous escalation in the recent past. The mobile phones of today are capable of being cameras taking pictures and videos, able to browse the Internet, do video calling and much more than an yesteryear computer. Due to the variety and the amount of information that is being transmitted the demand for spectrum resources i

Test application and test design, performed to ensure the production of fault-free chips, are becoming complicated and very expensive, especially in the case of SoCs (System-on-Chip), as the number of possible faults in a chip is increasing dramatically due to the technology development. It is therefore important to take test design into consideration as early as possible in the SoC design-flow in

Classical B lymphocyte activation is dependent on BCR cross-linking in combination with physical interaction with Th cells. Other B cell molecules that contribute to the activation are complement, cytokine, and TLRs recognizing specific pathogen-associated molecular patterns. Moraxella (Branhamella) catarrhalis is a common Gram-negative respiratory pathogen that induces proliferation in human IgD-

Metabolic complications are prevalent in individuals treated with cranial radiotherapy (CRT) for childhood acute lymphoblastic leukemia (ALL). The hypothalamus is a master regulator of endocrine and metabolic control. The aim of this study was to investigate whether the hypothalamic volume would be associated to metabolic parameters in ALL survivors. Thirty-eight (21 women) survivors participated

Vilka utmaningar skapar den globala rättviserörelsen för äldre och nyare teorier om sociala rörelser? I denna text diskuteras dels traditionella teorier som Marx och Sombarts, dels teorierna om "nya sociala rörelser" (Touraine med flera). Denna diskussion kompletteras med presentationen av data från en enkätundersökning gjord vid lokala sociala forum i Sverige.

Diabetic kidney disease is the leading cause of end-stage renal disease. Genetic factors have been suggested to contribute to its susceptibility. However, results from genetic studies are disappointing possibly because the role of glucose in diabetic kidney disease predisposed by epigenetic mechanisms has not been taken into account. Since thioredoxin-interacting protein (TXNIP) has been shown to

Interannual variability in meteorological dryness and wetness in central Finland during the period 1959–2009 was analysed using Standardized Precipitation Index (SPI) on three timescales (annual, seasonal and monthly). For different time steps (12, 3 and 1 months) of SPI values (SPI12, SPI3 and SPI1), trends based on the Mann-Kendall non-parametric test and the most significant relationships with

The Goto-Kakizaki (GK) rat is a well-studied non-obese spontaneous type 2 diabetes (T2D) animal model characterized by impaired glucose-stimulated insulin secretion (GSIS) in the pancreatic beta cells. MicroRNAs (miRNAs) are short regulatory RNAs involved in many fundamental biological processes. We aim to identify miRNAs that are differentially-expressed in the pancreatic islets of the GK rats an