Determination of Mass- and Heat Transfer Coefficients for Computer Modelling of Pharmaceutical Freeze-Drying
This thesis work deals with the determination of mass- and heat transfer coefficients for pharmaceutical vial freeze-drying and the one-dimensional steady state computer modelling of primary drying. The overall heat transfer coefficient K_V for the vial/freeze-dryer system was successfully determined using a gravimetric method. The overall resistance to mass transfer R_p was successfully determine