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The European pressurized-water reactor between narratives and policies: exploring the French nuclear reactor design with a feasibility framework to assess wider implications for France and the EU

With fossil fuel-dependencies affecting energy generation, and renewables being contextually limited by intermittency and dispatchability issues, this work explores European Pressurized-water Reactors (EPRs) as a nuclear-based climate mitigation measure in France and in the EU. Through its conceptual framework, this paper evaluates the technical potential of EPRs through the gate-keeping effect of

Min tid i Alger : mellan makt och tillit i Algers diplomatiska rum under Henric Gottfrid Brandels konsulstillträde 1765–1768

"My memories from Algiers - Between power and trust in Algiers' diplomatic spaces during Henric Gottfrid Brandel's accession to the consular office 1765-1768." In 1764, Henric Gottfrid Brandel was appointed consular secretary to the Swedish consul in Algiers. He would remain as secretary until late 1765 and early 1766, when he was appointed as temporary consul by the then current

The Role of Designers in the Transition from a Linear to a Circular Economy

Research shows that a significant portion of the environmental impact from products is determined already in the design phase. Implementation of principles of Circular Economy (CE) in design practice has the potential to reduce waste and to encourage reuse of resources. Since designers are responsible for the design process, it is therefore relevant to investigate whether designers are properly eq

Proposing "sustainable meetings" : international convention bureaus positionings in the post covid time

Proposing “sustainable meetings”: convention bureaus marketing of destinations as ethicalIn the wake of a crisis and restrictions on physical interactions, the importance of meetings is emphasized more than ever. The meetings industry has gone from unprecedented down-sizing to higher booking rates than ever, and attracting meetings is an important part of municipalities place brandingstrategies. A

MicroRNA-9-3p : a novel predictor of neurological outcome after cardiac arrest

Aims: Resuscitated out-of-hospital cardiac arrest (OHCA) patients who remain comatose after hospital arrival are at high risk of mortality due to anoxic brain injury. MicroRNA are small-non-coding RNA molecules ultimately involved in gene-silencing. They show promise as biomarkers, as they are stable in body fluids. The microRNA 9-3p (miR-9-3p) is associated with neurological injury in trauma and

Hydride formation and dynamic phase changes during template-assisted Pd electrodeposition

We investigated the structural evolution of electrochemically fabricated Pd nanowires in situ by means of grazing-incidence transmission small- and wide-angle x-ray scattering (GTSAXS and GTWAXS), x-ray fluorescence (XRF) and two-dimensional surface optical reflectance (2D-SOR). This shows how electrodeposition and the hydrogen evolution reaction (HER) compete and interact during Pd electrodeposit

Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe

This is the first report comparing EULAR and national treatment recommendations for PsA patients across Europe, and the first this decade to compare ASAS-EULAR and national treatment recommendations in axSpA patients. An electronic survey was completed from October 2021–April 2022 by rheumatologists in 15 European countries. One and four countries followed all EULAR and ASAS-EULAR recommendations,

Putting appraisal in context : Appraisal of climate anxiety and the role of nature connectedness

Global climate change has increasing detrimental effects on mental health (e.g., in the form of climate anxiety), both through direct exposure to its consequences (e.g., extreme weather) and through indirect exposure (i.e., the social representation of climate change without direct contact to its physical consequences). To help people cope with the anxious response, nature connectedness is suggest

Mitochondrial heteroplasmic shifts reveal a positive selection of breast cancer

BACKGROUND: Breast cancer is, despite screening, not always detected early enough and is together with other tumor types known to shed genetic information in circulation. Unlike single-copy nuclear DNA, mitochondrial DNA (mtDNA) copies range from 100s to 10,000s per cell, thus providing a potentially alternative to identify potential missing cancer information in circulation at an early stage.METH

Argonaute, Vault, and Ribosomal Proteins Targeted by Autoantibodies in Systemic Lupus Erythematosus

OBJECTIVE: To expand, in an unbiased manner, our knowledge of autoantigens and autoantibodies in patients with systemic lupus erythematosus (SLE) and evaluate their associations with serological and clinical variables. METHODS: Human proteome arrays (> 21,000 proteins) were screened with serum from patients with SLE (n = 12) and healthy controls (n = 6) for IgG and IgA binding. Top hits were valid

Use of metal nanoparticles in agriculture. A review on the effects on plant germination

Agricultural nanotechnology has become a powerful tool to help crops and improve agricultural production in the context of a growing world population. However, its application can have some problems with the development of harvests, especially during germination. This review evaluates nanoparticles with essential (Cu, Fe, Ni and Zn) and non-essential (Ag and Ti) elements on plant germination. In g

Simulating surface soil moisture on sandy beaches

A model that simulates surface moisture content on sandy beaches for aeolian transport applications is developed and integrated into the aeolian transport model AeoLiS. The moisture content of a thin surface layer (≈2 mm thickness) is computed as a function of wave runup, precipitation, evaporation, percolation, and capillary rise from the groundwater table. The groundwater table is simulated usin

Mechanisms underpinning recruitment of the HUSH-MORC2 corepressor to transposable elements in neural progenitor cells

The HUSH-MORC2 corepressor has emerged as a key player in epigenetic silencing of L1 retrotransposons and other mobile genetic elements during human development. In the ‘canonical’ mode of its recruitment to chromatin, HUSH makes interactions with nascent transcripts from target elements, leading to the assembly of SETDB1, which deposits the repressive heterochromatin mark H3K9me3, and chromatin r