Archaeological radiocarbon dating in coastal northern Hokkaido is challenged by the marine reservoir effect and the scarcity of materials with terrestrial carbon sources. This has contributed to gaps and general uncertainty in the timing of the region's culture-historical periods. The Late Holocene site of Hamanaka 2 on Rebun Island, featuring a stratified shell midden context with excellent prese

The crystal structures of domain-swapped tryptophan repressor (TrpR) variant Val58Ile before and after soaking with the physiological ligand l-tryptophan (l-Trp) indicate that l-Trp occupies the same location in the domain-swapped form as in native dimeric TrpR and makes equivalent residue contacts. This result is unexpected because the ligand binding-site residues arise from three separate polype

The end-Permian mass extinction was the most severe biotic crisis in Earth’s history. In its direct aftermath, microbial communities were abundant on shallow-marine shelves around the Tethys. They colonized the space left vacant after the dramatic decline of skeletal metazoans. The presence of sponges and sponge microbial bioherms has largely gone unnoticed due to the sponges’ size and the cryptic

As no one symptom can predict disease severity or the need for dedicated medical support in coronavirus disease 2019 (COVID-19), we asked whether documenting symptom time series over the first few days informs outcome. Unsupervised time series clustering over symptom presentation was performed on data collected from a training dataset of completed cases enlisted early from the COVID Symptom Study

This article investigates the production of religious literature published in Swedish from 1520 to 1599, specifically looking for translations of Luther’s texts. Previous research has concluded that Luther was relatively absent from the Swedish book market during the sixteenth Century – apart from translations of the Small Catechism and his Bible. In order to challenge previous research, the artic

Introduction: Data on outcome in persons with haemophilia B (PwHB) are limited and mainly extrapolated from studies of haemophilia A (HA). Aim: To characterize treatment outcomes in persons with severe HB in the Nordic region, with a focus on joint health, compared with matched controls with HA. Methods: PwHB attending haemophilia centres in Denmark, Finland, Norway and Sweden were enrolled and ma

In this article, we aim to provide general principles as well as personal views for colonic capsule endoscopy. To allow an in-depth understanding of the recommendations, we also present basic technological characteristics and specifications, with emphasis on the current as well as the previous version of colonic capsule endoscopy and relevant software. To date, there is no scientific proof to supp

We present a model for generating 3d articulated pedestrian locomotion in urban scenarios, with synthesis capabilities informed by the 3d scene semantics and geometry. We reformulate pedestrian trajectory forecasting as a structured reinforcement learning (RL) problem. This allows us to naturally combine prior knowledge on collision avoidance, 3d human motion capture and the motion of pedestrians

Highly responsive teachers tend to foster behaviors that are low in conflict and high in prosociality, among their students, leading to a positive classroom climate and to a decrease in bullying victimization. However, little is known about the interaction between teacher responsiveness and both student–teacher, and student–student relationship characteristics, in influencing students’ bullying vi

Background: Periodontitis is suggested to be associated with a risk of cardiovascular events. Using periodontal treatment recorded in Swedish national registries as a surrogate marker, we aimed to investigate whether periodontitis was associated with a first myocardial infarction. Methods: This nationwide case-control study, with data from national registries, involved 51,880 individuals with a fi

Background: Congenital diaphragmatic hernia (CDH) reportedly has neurologic consequences in childhood however little is known about the impact in isolated CDH. Aims: Herein we aimed to describe the risk of neurodevelopmental complications in children born with isolated CDH. Materials & Methods: We systematically reviewed literature for reports on the neurological outcome of infants born with i

We study the long-term impact of a policy-driven change in childhood nutrition. For this purpose, we evaluate a program that rolled out nutritious school lunches free of charge to all pupils in Swedish primary schools between 1959 and 1969. We estimate the impact of the program on children's economic, educational, and health outcomes throughout life. Our results show that the school lunch program

Research has demonstrated how ignorance is made, manipulated and called upon; how it is the result of strategies, activities and structures. This article extends the literature on ignorance by exploring actors’ own explanations of their self-inflicted ignorance following acts of ignoring. By means of a case analysis, we explore how actors explain and justify ignoring data they themselves produced.

This presentation discusses two examples of participatory sense-making, that fall within the ecological-enactive trajectory of my artistic research. The first work is Tapeshavet, a collaboration between composer Anders Hultqvist, poet Gunnar D. Hansson and ecological sound artist Stefan Östersjö and I, with the first output premiered at GAS festival in Sweden in autumn 2018 and a larger work set f

BACKGROUND: Bladder cancers have high total mutation burdens resulting in genomic diversity and intra-and inter-tumor heterogeneity that may impact the diversity of gene expression, biologic aggressiveness, and potentially response to therapy. To compare bladder cancers among patients, an organizational structure is necessary that describes the tumor at the histologic and molecular level. These 'm

Introduction: Percutaneous ultrasound-guided core needle biopsy is a well-established method in the diagnosis of musculoskeletal tumors. It is unclear which factors contribute the most to a successful biopsy. The aim of the study was to determine the value of ultrasound-guided core needle biopsy of solid lesions in the musculoskeletal system using a 16-gauge needle. Material and methods: A retrosp