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Regression trees are evaluated with respect to mean square error (MSE), mean integrated square error (MISE), and integrated squared error (ISE), as the size of the training sample goes to infinity. The asymptotically MSE- and MISE minimizing (locally adaptive) regression trees are characterized. Under an optimal tree, MSE is O(n^{-2/3}). The estimator is shown to be asymptotically normally distrib
Streptococcus pyogenes is an exclusively human pathogen that can provoke mild skin and throat infections but can also cause fatal septicemia. This gram-positive bacterium has developed several strategies to evade the human immune system, enabling S. pyogenes to survive in the host. These strategies include recruiting several human plasma proteins, such as the complement inhibitor, C4b-binding prot
Several studies have shown that time domain reflectometry (TDR) can be used to measure water content and solute concentration during steady-state experiments with constant soil water content. Few studies have been carried out to identify the relationship between bulk electrical conductivity (σa) and soil solution electrical conductivity (σw) to be used for transient conditions with varying water c
Phosphorylcholine (PC) is an epitope on oxidized low-density lipoprotein (oxLDL), apoptotic cells and several pathogens like Streptococcus pneumoniae. Immunoglobulin M against PC (IgM anti-PC) has the ability to inhibit uptake of oxLDL by macrophages and increase clearance of apoptotic cells. From our genome-wide association studies (GWASs) in four Europeanancestry cohorts, six single nucleotide p
We experimentally explore the role of collective incentives in sustaining cooperation in finitely repeated public goods games with imperfect monitoring. In our experiment players only observe noisy signals about individual contributions, while total output is perfectly observed. We consider sanctioning mechanisms that allow agents to commit to collective punishment in case total output fall short
Although Singapore, a linguistically and ethnically diverse city–state, uses four official languages, namely Malay, Mandarin, Tamil, and English, which are supposed to enjoy equal status, there appears to be a pecking order to these languages. English seems to be the dominant language when taking into consideration the bilingual education policy, numerous campaigns promoting its use in terms of sp
Rye kernel bread (RKB) evening meals improve glucose tolerance, enhance appetite regulation and increase satiety in healthy volunteers. These beneficial effects on metabolic responses have been shown to be associated with increased gut fermentation. The present study aimed to elucidate if RKB evening meals may cause rapid alterations in microbiota composition that might be linked to metabolic-, im
Pedagogik är en av de klassiska vetenskapliga disciplinerna och har som universitetsämne en hundraårig tradition. I takt med att samhället förändras har även det innehåll som sysselsätter pedagogiken ändrats. Var befinner sig det vetenskapliga ämnet pedagogik i dag? Hur ser den historiska bakgrunden till ämnets framväxt ut? Vilka är de fundament som håller samman pedagogikämnet? Vilka framtida utm
Quantitative imaging, where every pixel of an image represents a physical quantity (e.g. timeor velocity) is being increasingly used in the field of diagnostic radiology and has potential toenhance medical diagnosis. Quantitative methods for Magnetic Resonance Imaging (MRI)enables measurements of velocity and flow using a technique called Phase Contrast MagneticResonance (PC-MR), and different tim
If not accounted for, temperature effects on the water content and electrical conductivity measured with time domain reflectometry (TDR) will introduce significant errors. In this study, an automated TDR system was used to quantify the temperature dependence of the apparent dielectric constant and electrical conductivity in wet soils. Sandy, clayey, and organic soils were used to examine the effec
Co-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in thCo-creation (or co-production, Voorberg et al., 2015) of public services together with individual service users is based on the assumption that the individual can define her or his own value to be co-created. However, in the case of children, this can be put into doubt, as children do not have the same cognitive perspectives and abilities as adults, and a weaker voice as agents. This results in th
Large volumes of wastewater with dissolved wood components are treated in wastewater treatment plants at thermomechanical pulp mills. It has been shown previously that hemicelluloses in these wastewater streams can be recovered by membrane filtration. A serious obstacle when treating lignocellulose process streams is fouling of the membranes. Fouling not only increases operating costs but also red
Modelling solute transport in the unsaturated zone is a complex problem given the inherent soil heterogeneity. Using time domain reflectometry (TDR) as described in this paper can improve data quality to be used in predictive models. The TDR technique requires appropriate calibration if it is to be used for solute concentration measurements under constant and varying water content. Two ways of det
