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Two common structural motifs for TCR recognition by staphylococcal enterotoxins

Superantigens are toxins produced by Staphylococcus aureus, called staphylococcal enterotoxins (abbreviated SEA to SEU). They can cross-link the T cell receptor (TCR) and major histocompatibility complex class II, triggering a massive T cell activation and hence disease. Due to high stability and toxicity, superantigens are potential agents of bioterrorism. Hence, antagonists may not only be usefu

Provoking, disturbing, hacking : Media archaeology as a framework for the understanding of contemporary DIY composers’ instruments and ideas

The article is a discussion of works by two Danish composers who both, with self-constructed instruments challenge computer music both as genre, the understanding and use of conventional technology and the relation to history. At first glance, the use of the homemade instruments appears as a common characteristic. But, when one takes a closer look, different discourses and various discussions of m

Retroutopier : Transmediale og CTM 2013

Under årets kallaste tid värmdes Berlin av två särpräglade festivaler: Transmediale och CTM (tidigare Club Transmediale). Elektroniska events, mystiska maskiner och forna framtidsdrömmar var centrala utgångspunkter i det täta programmet. En del magplask till trots, bjöd festivalen också i år på enastående upplevelser och intressanta reflektioner. Sanne Krogh Groth rapporterar från några intensiva Under årets kallaste tid värmdes Berlin av två särpräglade festivaler: Transmediale och CTM (tidigare Club Transmediale). Elektroniska events, mystiska maskiner och forna framtidsdrömmar var centrala utgångspunkter i det täta programmet. En del magplask till trots, bjöd festivalen också i år på enastående upplevelser och intressanta reflektioner. Sanne Krogh Groth rapporterar från några intensiva

The complement inhibitor factor H generates an anti-inflammatory and tolerogenic state in monocyte-derived dendritic cells

The activation of the complement system is a key initiating step in the protective innate immune-inflammatory response against injury, although it may also cause harm if left unchecked. The structurally related soluble complement inhibitors C4b-binding protein (C4BP) and factor H (FH) exert a tight regulation of the classical/lectin and alternative pathways of complement activation, respectively,

Family counts : deciding when to murder among the Icelandic Vikings

In small scale societies, lethal attacks on another individual usually invite revenge by the victim's family. We might expect those who perpetrate such attacks to do so only when their own support network (mainly family) is larger than that of the potential victim so as to minimise the risk of retaliation. Using data from Icelandic family sagas, we show that this prediction holds whether we consid

An EU Strategy for relations with Iran after the nuclear deal

This report outlines the potential for a more structured and strategic relationship between the European Union and the Islamic Republic of Iran following the Joint Comprehensive Plan of Action (JCPOA). To both address areas of disagreement and complaints, as well as pursue common interests and matters of mutual benefit, the EU needs to put in place an institutional framework that can withstand the

“Just trained to be a chef, not a leader:” A Study of Head Chefs ́ Practices

Hierarchical manners and taxing work complicate the picture of the restaurant industry, a sector in great need of personnel. There is little scientific research on daily work in restaurants. Through interviews and observations in restaurant kitchens, three head chef practices were detected: “Master the materiality” is a stipulation for leading kitchens, but does not imply leadership aspirations; “

Getting the picture of home lighting: Adding participant photography to the interview

This paper draws attention to the potential benefits of using photographs in combination with interviews, that is to say photo elicitation. As defined by Harper (2002), photo elicitation is “based on the simple idea of inserting a photograph into a research interview” (p. 13). The photographs can be taken by the researcher or the participant to evoke comments. If participants are asked to produce

The effect of high post-mortem temperature on the development of pale, soft and exudative pork : Interaction with ultimate pH

The effects of post-mortem temperature and ultimate pH (pHu, 24 h post mortem) on the development of the pale, soft and exudative (PSE) characteristics in pig longissimus dorsi muscle were studied. Ten out of the 13 pigs used received pre-slaughter injections of adrenaline in order to deplete muscle glycogen stores. The two muscles from each pig were held at 12 or 35°C during rigor mortis developm