Regulating RET receptor expression using targeted proteasomal degradation
Parkinson Disease (PD) is a neurodegenerative disease affecting many neurons in the brain. Particularly nigrostriatal Dopamine (DA) neurons of the substantia nigra pars compacta (SNpc) appear to be the epicenter of the disease. Cell death of these neurons is believed to be the primary cause for motor defects and many of the symptoms seen in PD patients. Many experimental therapies look to prevent
