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Does mesh implantation affect the spermatic cord structures after inguinal hernia surgery? An experimental study in rats

Background: Inguinal hernia repair is the most common operation in general surgery. Prosthetic reinforcement of the inguinal area with polypropylene mesh has increased dramatically in the last decade. The aim of this study was to evaluate how different types of mesh affect the spermatic cord structures. Methods: Thirty rats were divided into three groups. The spermatic cord was dissected free and

Hidden consumers in marketing - the neglect of consumers with scarce resources in affluent societies

Abstract Research in marketing has neglected economic scarcity in affluent societies, with a few exceptions. Many affluent states are today facing financial difficulties and a global belief in the market as self-regulating, and in de-regulation have led to a focus on consumer agency. This has also contributed to a widening gap regarding opportunities to consume in affluent societies. The purpose o

An ecosystem model-based estimate of changes in water availability differs from water proxies that are commonly used in species distribution models

To assess whether the water availability measures commonly used in species distribution models might be misleading because they do not account for the hydrological effects of changes in vegetation structure and functioning. Europe. We compared different methods for estimating water availability in species distribution models with the soil water content predicted by a process-based ecosystem model.

Arterial pulse wave velocity with tissue doppler imaging

This paper describes a new noninvasive ultrasonic method for estimating pulse wave velocity (PWV), an important physical parameter for characterizing the elastic properties of the arterial walls. The method utilizes a relatively new color Doppler modality for measuring tissue motion (tissue Doppler imaging or TDI). In contrast to previously proposed methods, the TDI modality offers multiple record

Galanin-positive nerves of trigeminal origin innervate rat cerebral vessels

(GAL)-positive nerve fibers in rat cerebral vessels were demonstrated by immunohistochemistry, and their origin in the trigeminal ganglia and pathway in the nasociliary nerve to the vessels was shown by retrograde tracer technique and nerve transection. Some fibres in the vertebrobasilar system appear to originate in extracranial sources. With the antiserum used only few GAL fibers could be seen i

Two-photon excitation in fluorescence polarization receptor-ligand binding assay

Fluorescence polarization is one of the most commonly used homogeneous assay principles in drug discovery for screening of potential lead compounds. In this article, the fluorescence polarization technique is combined with 2-photon excitation of fluorescence. Theoretically, the use of 2-photon excitation of fluorescence increases the volumetric sensitivity and polarization contrast of fluorescence

Using panel data to increase the power of modified unit root tests in the presence of structural breaks

When testing for unit roots using the Dickey-Fuller test, the presence of structural breaks can cause serious size distortions to the test. Previous research has suggested two modified tests, the weighted symmetric and the recursively mean-adjusted test, that has robust size properties even in the presence of a structural break. However, recent findings have shown that the power of the two modifie

Enzymatic fatty acid exchange in glycerophospholipids

Lipases can be used to exchange fatty acids in the sn-1 position of glycerophospholipids and phospholipase A2 is useful for the corresponding exchange reaction in the sn-2 position. In both cases, the exchange can be done in a one-step acidolysis process or in a two-step process. In the latter case, the original fatty acid in the desired position is removed by enzymatic hydrolysis or alcoholysis a

Utilisation of antihyperglycaemic drugs in ten European countries: different developments and different levels.

Aims/hypothesis The aim of this study was to compare developments in the utilisation of antihyperglycaemic drugs (AHGDs) in ten European countries. Subhect and methods Data on the yearly utilisation of insulin and oral AHGDs were collected from public registers in Denmark, Finland, Norway, Sweden, Belgium, England, Germany, Italy, Portugal and Spain, and were expressed as defined daily doses per 1

Viscoelasticity of a nonionic lamellar phase

The linear viscoelastic properties of a nonionic lamellar phase in C-orientation were studied as a function of temperature by small-amplitude oscillatory measurements in the frequency range 0.5-5 Hz. An almost solidlike elastic response was observed at all studied temperatures, from 42 to 20 degrees C. In this range, the elastic modulus was found to increase strongly with decreasing temperature. T

A label of health: a previous immune challenge is reflected in the expression of a female plumage trait.

Studies of ornaments as indicators of individual quality have hitherto focused on males, while studies of female ornaments have been almost absent. However, females within the same species may show large variation in both outer appearance and individual quality. We experimentally examined the effect of an immune challenge on the size of white fringes in the wing feathers produced one to two months

Knowledge sharing in project appraisals of coastal zone management – towards increased transparency in the decision process

n this article we discuss coastal erosion, efforts to deal with it and its associated problems on both a national and international basis, and difficulties in making long-range predictions of it. We emphasise the need to: assemble and share knowledge, information and experience in this area internationally; upgrade shoreline management guidelines; employ the latest methods and techniques for comba

Wireless Esophageal pH Monitoring Is Better Tolerated than the Catheter-Based Technique: Results from a Randomized Cross-Over Trial.

OBJECTIVES: Esophageal pH monitoring using a wireless pH capsule has been suggested to generate less adverse symptoms resulting in improved patient acceptance compared with the catheter-based method although evidence to support this assumption is lacking. The aim of this study was to evaluate and compare the subjective experience of patients undergoing both techniques for esophageal pH monitoring.

Lactoferricin treatment decreases the rate of cell proliferation of a human colon cancer cell line.

Food components modify the risk of cancer at a large number of sites but the mechanism of action is unknown. In the present investigation, we studied the effect of the peptide lactoferricin derived from bovine milk lactoferrin on human colon cancer CaCo-2 cells. The cells were either untreated or treated with 2.0, 0.2, or 0.02 microM lactoferricin. Cell cycle kinetics were investigated with a brom

Metabolic rate and thermal conductance of lemmings from high-arctic Canada and Siberia

The arctic climate places high demands on the energy metabolism of its inhabitants. We measured resting (RMR) and basal metabolic rates (BMR), body temperatures, and dry and wet thermal conductances in summer morphs of the lemmings Dicrostonyx groenlandicus and Lemmus trimucronatus in arctic Canada, and the BMR of D. torquatus, D. groenlandicus, L. sibiricus, L. bungei and L. trimucronatus in Sibe

Health claims in Europe: new legislation and PASSCLAIM for substantiation.

A regulation on nutrition and health claims made on foods was introduced in the European Union in 2007. This Regulation provides opportunities for the use of health claims on foods in Europe, including reduction of disease risk claims. The Regulation will be fully implemented by January 2010. A community list of permitted and rejected claims will be established and made available to the public. So

Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels - A meta-analysis of 21 cohort studies including more than 300,000 persons

Background: The extent to which moderate overweight (body mass index [BMI], 25.0-29.9 [calculated as weight in kilograms divided by height in meters squared]) and obesity ( BMI, >= 30.0) are associated with increased risk of coronary heart disease (CHD) through adverse effects on blood pressure and cholesterol levels is unclear, as is the risk of CHD that remains after these mediating effects are

Perturbations of Jordan matrices

We consider perturbations of a large Jordan matrix, either random and small in norm or of small rank. In the case of random perturbations we obtain explicit estimates which show that as the size of the matrix increases, most of the eigenvalues of the perturbed matrix converge to a certain circle with centre at the origin. In the case of finite rank perturbations we completely determine the spectra

Challenging the importance of size as determinant for CSR activities

Purpose – This paper aims to contribute to the development and understanding of corporate social responsibility (CSR) by discussing two interrelated characteristics of current literature: a tendency in discourses to portray CSR as equal to the societal activities displayed by and demanded from large, multinational firms; and an increasing focus on and description of “small firm CSR” in research. T

Iodixanol 320 results in better renal tolerance and radiodensity than do gadolinium-based contrast media: Arteriography in ischemic porcine kidneys

Purpose: To prospectively compare nephrotoxicity and radiodensity of plasma hyperosmotic gadolinium chelates (attenuation-osmotic ratio of 1: 1) with those of plasma iso-osmotic iodine-based contrast media (attenuation-osmotic ratio of 3: 1 or 6: 1) after renal arteriography in ischemic porcine kidneys. Materials and Methods: The local animal care committee approved this study. The following contr