ABSTRACT: Neuroinflammation is implicated in the development and maintenance of persistent pain states, but there are limited data linking cerebrospinal fluid (CSF) inflammatory mediators with neurophysiological pain processes in humans. In a prospective observational study, CSF inflammatory mediators were compared between patients with osteoarthritis (OA) who were undergoing total hip arthroplast

Background: Finn Chambers AQUA (FCA) is a development of the Finn Chambers (FC) test system in which the test chambers are mounted on a moisture-resistant adhesive patch. FCA has pre-fixed filter papers. Because the use of FCA does not require any extra taping or use of separate filter papers, a change from FC to FCA chambers may be beneficial for both patients and patch-test technicians. Objectiv

The glabrous skin around the nostrils in mammals is called a rhinarium or planum nasale. Rhinarium skin has multiple epidermal domes that are generally assumed to form a tactile surface. The rhinarium is innervated by a branch of the trigeminal nerve which is associated with stimuli such as touch, chemical irritants and temperature. In this study, our aim was to correlate variation in rhinarium sk

Aims and objectives: To describe nurses' experiences of a child-centred family guided intervention of obesity tested within the child health services targeting children identified with overweight and their caregivers. Background: Interventions aiming to support families towards a healthier lifestyle can lead to decreased risk of overweight evolving into obesity in a child. At the same time, nurses

Linear Parameter Varying (LPV) models can be used to describe the vehicular lateral dynamic behavior of self-driving cars. They are particularly suitable for model-based control schemes such as model predictive control (MPC) applied to real-time trajectory tracking control, since they provide a proper trade-off between accuracy in different scenarios and reduced computation cost compared to nonlin

The use of concepts is a vital part of the research process. Many researchers overexploit popular concepts by adding more and more vague and poorly defined meanings to them, thereby making their boundaries unclear and the concepts increasingly unwieldy. We will refer to these types of concepts as hembigs – an acronym for hegemonic, ambiguous, big concepts. The article demonstrates the problem in t

Background and purpose: Various blood biomarkers reflecting brain amyloid-β (Aβ) load have recently been proposed with promising results. However, to date, no comparative study amongst blood biomarkers has been reported. Our objective was to examine the diagnostic performance and cost effectiveness of three blood biomarkers on the same cohort. Methods: Using the same cohort (n = 68), the performan

Chapter about the reactions to and reception of the arrival of refugees in Octover and November 1943 and during the spring of 1945 in the south of Sweden.

The Open Porous Media (OPM) initiative is a community effort that encourages open innovation and reproducible research for simulation of porous media processes. OPM coordinates collaborative software development, maintains and distributes open-source software and open data sets, and seeks to ensure that these are available under a free license in a long-term perspective. In this paper, we present

We present an adaptive Discontinuous Galerkin discretization for the solution of porous media flow problems. The considered flows are immiscible and incompressible. The fully adaptive approach implemented allows for refinement and coarsening in both the element size, the polynomial degree and the time step size.

We defne a weak compatibility condition for the Newest Vertex Bisection algorithm on simplex grids of any dimension and show that, using this condition, the iterative refnement algorithm terminates successfully. Additionally we provide an O(n) algorithm that renumbers any simplex grid to fulfll this condition. Furthermore we conduct experiments to estimate the distance to the standard compatibilit

The existing information supports the use of this material as described in this safety assessment. Glyceryl monooleate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that glyceryl monooleate is not genotoxic. Data on glyceryl monooleate provide a cal

Epicardial adipose tissue has a paracrine effect, enhancing coronary artery atherosclerotic plaque development. This study evaluated epicardial fat volume (EFV), adipokines, coronary atherosclerosis, and adverse cardiovascular events in a cohort of asymptomatic patients with type 2 diabetes mellitus (T2DM). Epicardial fat volume was calculated using data from computed tomography coronary angiogram