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Radioimmunotherapy of prostate cancer targeting human kallikrein-related peptidase 2

Background: Prostate cancer ranks as the second most lethal malignancy in the Western world. Previous targeting of prostate-specific antigen and human kallikrein-related peptidase 2, two related enzymes abundantly expressed in prostatic malignancies, with radioimmunoconjugates intended for diagnostic purposes, have proven successful in rodent prostate cancer (PCa) models. In this study, we investi

Organic farming affects the potential of a granivorous carabid beetle to control arable weeds at local and landscape scales

Organic farming not only increases plant diversity, but also simultaneously promotes biological weed control through provisioning of ample resources to seed predators. Harpalus affinis (Schrank, 1781) was collected from organically or conventionally managed winter-wheat fields with high or low surrounding shares of organic fields, aiming to test the impact of agricultural management on its activit

Homogenization of lepidopteran communities in intensively cultivated agricultural landscapes

Landscape simplification and habitat fragmentation may cause severe declines of less mobile and habitat specialist species and lead to biotic homogenization of species communities, but large-scale empirical evidence on biotic homogenization remains sparse. We sampled butterfly and day-active geometrid moth communities within 134 differently fragmented landscapes in Finland situated in five geograp

Role of organic and conventional field boundaries on boreal bumblebees and butterflies

This study examined how field boundary habitat quality and farming system (organic or conventional) affect species richness and abundance of diurnal lepidopterans and bumblebees in boreal agricultural landscapes. The results showed positive effects of field boundary area on lepidopteran diversity, as well as positive effects of nectar flower abundance on lepidopterans and bumblebee abundance. Orga

Synthesis, spectroscopic characterization and catalytic activity of platinum(II) carbene complexes

A novel platinum complex with 1,3-bis(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazol-2-ylidenyl ligand has been synthesized and characterized on the basis of elemental analysis, MS, 1H and 13C NMR spectroscopy, X-ray Absorption Spectroscopy and single crystal X-ray diffraction studies. The XRD determination of the complex (monoclinic, C2/c) revealed a structure in which the platinum (II) centre co

Tractor Incidence on Swedish roads

Compared with other industries, agriculture is the most dangerous branch in Sweden. In 2004,at least one injury occurred on 8% of Swedish farms that resulted in body impairments andconstituted obstacle at work. Beside the injuries that occured on the farms farmers also areinvolved in incidents with tractors and other slow-moving vehicles (SMVs) on the roadsoutside the farms.

Quality of Government

The authors argue that the concept of quality of government should be best understood as that of having impartial government institutions. This definition avoids functionalism, ignores the contents of specific policies in favor of the procedures for how they are implemented, and pertain to the output side of the political system. They discuss this concept in relation to several proposed alternativ

Implementation of a Highly-Parallel Soft-Output MIMO Detector with Fast Node Enumeration

This paper presents a high throughput, low latency soft-output signal detector for a 4×4 64-QAM MIMO system. To achieve high data-level parallelism and accurate soft information, the detector adopts a node perturbation technique to generate a list of candidate vectors around Zero Forcing, ZF, result. Additionally a fast and hardware friendly node enumeration scheme is developed to significantly re

Multi-echelon Inventory Control with Integrated Shipment Decisions

Rising fuel prices and increasing environmental awareness emphasizes the importance of the transportation aspect in logistics. This calls for new improved inventory control methods that consider the effects of shipment strategies in a more realistic manner. This thesis, consisting of an introduction and three scientific papers, studies how shipment decisions can be included in the inventory contro

A Digitally Controlled Low-Power Clock Multiplier for Globally Asynchronous Locally Synchronous Designs

Partitioning large high-speed globally synchronous ASICs into locally clocked blocks reduces clock skew problems and if handled correctly it also reduces the power consumption. However, to achieve these positive effects, the blocks need on-chip clock generators having properties such as small area and low power consumption. Therefore, a low power, high frequency, small area digitally controlled on