A combination of NMR chemical shift imaging and self-diffusion experiments is shown to give a detailed molecular picture of the events that occur when tablets of hydrophobically modified poly(acrylic acid) loaded with a drug (griseofulvin) swell in water in the presence or absence of surfactant (sodium octylbenzenesulfonate). The hydrophobic substituents on the polymer bind and trap the surfactant

Ankylosing Spondylitis (AS) is a chronic, potentially disabling, inflammatory disease that poses a longstanding burden on the patient and the society. The epidemiology of AS in Sweden has not been extensively studied previously. Radiographic and self-perceived health information from 1,005 men aged 69-81 years, showed a prevalence of moderate to severe radiographic sacroiliitis of 1.4% (95% Confid

Background. The aim of this study was to determine the relationship between single-nucleotide polymorphisms (SNPs) in MRP2 genes and mycophenolic acid (MPA) pharmacokinetics in renal transplant recipients of the Symphony Pharmacogenomic substudy. Methods. Sixty-six renal transplant recipients of eight Spanish centres were randomized into four branches of immunosuppressive regimen: low dose of cycl

We simulated and experimentally investigated the sputter yield of ZnO and GaAs nanowires, which were implanted with energetic Mn ions at room temperature. The resulting thinning of the nanowires and the dopant concentration with increasing Mn ion fluency were measured by accurate scanning electron microscopy (SEM) and nano-x-Ray Fluorescence (nanoXRF) quantification, respectively. We observed a cl

Uncommon categorization, i.e. disparities in how similar terms and information is interpreted, coded and categorized, has been shown to impede inter-agency communication and collective sense-making. This study focuses on the presence and effects of uncommon categorizations in disaster risk management systems. We use the Swedish disaster risk management system as our case, and our empirical data co

Ketamine an intravenous anesthetic and a major drug of abuse, is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. Ketamine's enantiomer. S(+)-ketamine, acts stereoselectively on neuronal NMDA receptors. The purpose of this in vitro study was to compare the direct effects of S(+)-ketamine. 2 other noncompetitive NMDA receptor antagonists (dextrorphan and dextromethorphan), and the

Den första fastoxidbränslecellen (SOFC) utvecklades redan 1937, dock har den stora kommersialiseringen väntat. Under 2012 förväntas 20 MW SOFC-system att levereras till kund, att jämföras med 1,3 MW under 2008. Det är främst inom specifika nischmarknader, t.ex. lokal kraftgenerering till datacenter, småskalig kraftvärme för enskilda hushåll samt för militära ändamål där SOFC-system är tillgängliga

Most musculoskeletal soft tissue tumors are benign, lipoma being the most common. Malignant soft tissue tumors may be difficult to clinically distinguish from benign.Scandinavian recommendations are that all lesions suspicious for sarcoma be referred to a sarcoma center. This has led to improved tumor control and less post-operative functional deficits.Magnetic resonance imaging (MRI) can reliably

Charge transfer pathways and charge transfer times in molecular films and in adsorbate layers depend both on the details of the electronic structure as well as on the degree of the initial localization of the propagating excited electronic state. For C6F6 molecular adsorbate films on the Cu(111) surface we determined the interplay between excited state localization and charge transfer pathways. In

Objective Several families with characteristic features of hereditary myopathy with early respiratory failure (HMERF) have remained without genetic cause. This international study was initiated to clarify epidemiology and the genetic underlying cause in these families, and to characterise the phenotype in our large cohort. Methods DNA samples of all currently known families with HMERF without mole

We have investigated growth of thin epitaxial layers of InAs on Si (1 1 1) substrates by metalorganic vapor phase epitaxy (MOVPE) and successfully grown GaSb layers on InAs. Furthermore, we have studied the effect of growth temperature and material flow on the nucleation stage and also nucleated GaSb nanowires on the underlying GaSb layer. The InAs layers are grown by a standard two-step growth ap

Creating innovations that successfully meet societal challenges on a grand scale involves great vision, great ideas and great execution. While coming up with a plethora of ideas is undoubtedly critical to innovation, many individuals, teams and organizations are lacking insight into how to practically move forward beyond the great idea without losing touch with the overall vision. This article des

Abstract is not available

"Contentment in the moment" is a classic grounded theory exploring safety and contentment within a small community in northern Norway. The purpose of the study was to explore the village's everyday life from a participant's perspective and to develop an understanding of their living conditions. We found different survival strategies, which have their roots in the village's history of poverty, isol

OBJECTIVE: Employment rates are significantly lower among individuals with arthritis compared to a general population. There is, however, limited research about how men with arthritis perceive their ability to maintain working. The aim of this study was thus to explore their perception of this. PARTICIPANTS: Nine employed men with arthritis were purposively sampled. METHODS: Interviews were perfor

The hyperfine structure of a large number of transitions in Al II cannot be described using A and B hyperfine constants and the hyperfine structure is therefore said to be anomalous. In this paper, we have studied the hyperfine structure of a few transitions in Al II, 3s5s(3)S-3s5p(3)P, 3s4d(3)D-3s5p(3)P and 3s5p(3)P-3s5d(3)D, by combining theory and experiment. It is shown that the anomalous hype

Fresh water availability and demand are unevenly distributed both temporally and geographically. Furthermore, the availability of fresh water has remained more or less constant, while the demand for clean water is steadily increasing. With demand surpassing supply, an integrated water resource management approach is required to ensure even distribution of potable water to all levels of society whi

Recension av Anders Wahlgren, Vasa 1628 – människorna, skeppet, tiden.

The influence of Thermomyces lanuginosus lipase (TLL) on the phase behaviour of liquid-crystalline phases of aqueous phytantriol as well as conformational changes of TLL entrapped in the cubic Q(230) phase have been studied by small angle X-ray diffraction (SAXD), FT-Raman, and FT-IR techniques. It was found that the lipidic Q(230) Phase is able to accommodate up to 10 wt.% of TLL, and the tempera