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Antiproliferative effects of sea buckthorn (Hippophae rhamnoides L.) extracts on human colon and liver cancer cell lines

Sea buckthorn berries contain many bioactive compounds that have anticancer properties. To investigate whether the anti proliferative effects Could be associated with the presence of certain compounds. a sequential extraction was performed. The extraction started with heptane followed by ethyl acetate, ethanol, and water. A second protocol using ethanol:water (1:1) was also used. The contents of t

Stroke Incidence, Recurrence, and Case-Fatality in Relation to Socioeconomic Position. A Population-Based Study of Middle-Aged Swedish Men and Women.

BACKGROUND AND PURPOSE: Low socioeconomic status is associated with increased incidence of stroke. This study investigated stroke incidence, recurrence, and case-fatality after stroke among middle-aged Swedish men and women and whether this association differs by gender or stroke subtype. METHODS: A total of 69 625 (49% men) citizens, aged 40 to 65 years, living in the city of Malmö in 1990 were s

Measures and time points relevant for post-surgical follow-up in patients with inflammatory arthritis: a pilot study

Background: Rheumatic diseases commonly affect joints and other structures in the hand. Surgery is a traditional way to treat hand problems in inflammatory rheumatic diseases with the purposes of pain relief, restore function and prevent progression. There are numerous measures to choose from, and a combination of outcome measures is recommended. This study evaluated if instruments commonly used i

He and Ne in individual chromite grains from the regolith breccia Ghubara (L5): Exploring the history of the L chondrite parent body regolith

Abstract We analyzed He and Ne in chromite grains from the regolith breccia Ghubara (L5), to compare it with He and Ne in sediment-dispersed extraterrestrial chromite (SEC) grains from mid-Ordovician sediments. These SEC grains arrived on Earth as micrometeorites in the aftermath of the L chondrite parent body (LCPB) breakup event, 470 Ma ago. A significant fraction of them show prolonged exposure

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors

Whether signals mediated via growth factor receptors (GFRs) might influence lineage fate in multipotent progenitors (MPPs) is unclear. We explored this issue in a mouse knockin model of gain-of-function Flt3-ITD mutation because FLT3-ITDs are paradoxically restricted to acute myeloid leukemia even though Flt3 primarily promotes lymphoid development during normal hematopoiesis. When expressed in MP

Delivering and participating in a psycho-educational intervention for family caregivers during palliative home care: a qualitative study from the perspectives of health professionals and family caregivers.

Family caregivers in palliative care have a need for knowledge and support from health professionals, resulting in the need for educational and supportive interventions. However, research has mainly focused on the experiences of family caregivers taking part in interventions. To gain an increased understanding of complex interventions, it is necessary to integrate the perspectives of health profes

Embodying law in the garden: An autoethnographical account of an office of law

Based on an autoethnographical study of the office of the tingsnotarie this article questions the relation between the ethical self and the act of taking up a judicial office, employing the question of how I can live with (my) law. While the office and the ethical self are kept apart, often by recourse to persona, I make a case for the attendance to the self in examinations of ethical responsibili

Fermi Large Area Telescope and Multi-Wavelength Observations of the Flaring Activity of Pks 1510-089 between 2008 September and 2009 June

We report on the multi-wavelength observations of PKS 1510-089 (a flat spectrum radio quasar (FSRQ) at z = 0.361) during its high activity period between 2008 September and 2009 June. During this 11 month period, the source was characterized by a complex variability at optical, UV, and gamma-ray bands, on timescales down to 6-12 hr. The brightest gamma-ray isotropic luminosity, recorded on 2009 Ma

Nanowires With Promise for Photovoltaics

Solar energy harvesting for electricity production is regarded as a fully credible future energy source: plentiful and without serious environmental concerns. The breakthrough for solar energy technology implementation has, however, been hampered by two issues: the conversion efficiency of light into electricity and the solar panel production cost. The use of III-V nanowires (NWs) in photovoltaics

High-spin spectroscopy of Nd-140

The population of the high-spin states in Nd-140 was investigated using the reaction Zr-96(Ca-48,4n). The results from two experiments, one with the EUROBALL array and one with the JUROGAM II + RITU + GREAT setup employing the recoil decay tagging technique, have been combined to develop a very detailed level scheme for Nd-140. Twelve bands of quadrupole transitions and eleven bands of dipole tran

Radar Observations of Arctic Bird Migration in the Beringia Region

Bird migration was recorded by tracking radar and visual observations in the Beringia region. The data were subdivided into seven areas extending from north of Wrangel Island southeastward toward the Bering Strait and then northwestward off the coast of Alaska to Point Barrow. The studies, which took place during a ship-based expedition between 30 July and 19 August 2005, recorded a total of 557 t

Receding Horizon Prediction by Bayesian Combination of Multiple Predictors

This paper presents a novel online approach of merging multiple different predictors of time-varying dynamics into a single optimized prediction. Different predictors are merged by recursive weighting into a single prediction using regularized optimization. The approach is evaluated on two different cases of data with shifting dynamics; one example of prediction using several approximate models of

Phosphite-induced changes of the transcriptome and secretome in Solanum tuberosum leading to resistance against Phytophthora infestans

Background: Potato late blight caused by the oomycete pathogen Phytophthora infestans can lead to immense yield loss. We investigated the transcriptome of Solanum tubersoum (cv. Desiree) and characterized the secretome by quantitative proteomics after foliar application of the protective agent phosphite. We also studied the distribution of phosphite in planta after application and tested transgeni

Breast cancer risk in women who fulfill high-risk criteria: at what age should surveillance start?

Family history is a strong predictor of hereditary breast cancer, particularly when it includes cases of early onset or bilateral breast cancers and multiple cases of breast or ovarian cancers. This article provides relative risks and cumulative risks of breast cancer in women whose family history indicates high risk. Specifically, the aim was to determine how many years earlier the high-risk wome

Real-Time Gas-Phase Imaging over a Pd(110) Catalyst during CO Oxidation by Means of Planar Laser-Induced Fluorescence.

The gas composition surrounding a catalytic sample has direct impact on its surface structure, which is essential when in situ investigations of model catalysts are performed. Herein a study of the gas phase close to a Pd(110) surface during CO oxidation under semirealistic conditions is presented. Images of the gas phase, provided by planar laser-induced fluorescence, clearly visualize the format

Parenthood and factors that influence outdoor recreational physical activity from a gender perspective

Background: A physically active life promotes both physical and mental health, increasing well-being and quality of life. Physical activity (PA) performed outdoors has been found to be particularly good for promoting well-being. However, participation in PA can change during the course of a lifetime. Parenthood has been found to be a life event associated with decreased PA, especially among women,