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A new small-angle X-ray scattering set-up on the crystallography beamline I711 at MAX-lab.
A small-angle X-ray scattering (SAXS) set-up has recently been developed at beamline I711 at the MAX II storage ring in Lund (Sweden). An overview of the required modifications is presented here together with a number of application examples. The accessible q range in a SAXS experiment is 0.009-0.3 A(-1) for the standard set-up but depends on the sample-to-detector distance, detector offset, beams
Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions.
The complement system is activated in the vasculature during thrombotic and inflammatory conditions. Activation may be associated with chronic inflammation on the endothelial surface leading to complement deposition. Complement mutations allow uninhibited complement activation to occur on platelets, neutrophils, monocytes, and aggregates thereof, as well as on red blood cells and endothelial cells
Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer
Popular Abstract in Swedish Cancer är ett laddat ord, och för de flesta av oss är cancern inte längre bort än hos en nära släkting eller vän. Trots den gemensamma benämningen, är cancer är inte bara en sjukdom, utan ca 200 olika som alla har gemensamt att cellerna börjar dela sig okontrollerat. Cancer är väldigt vanligt och uppskattningsvis kommer var tredje person att drabbas av cancer under sin Early diagnosis and reliable prognosis and treatment prediction of breast cancer will ultimately lead to a decreased mortality rate. This can be achieved by identification of prognostic and treatment predictive biomarkers, and by understanding the mechanisms behind early changes in the breast. The cell cycle is a closely controlled process, involving multiple components with regulation on several
Maternal use of thyroid hormones in pregnancy and neonatal outcome
Objective. To describe neonatal outcome including the presence of congenital malformations in infants born to women substituted with thyroid hormones, and the maternal characteristics of these women. Design. Register study based on prospectively collected data in relation to delivery. Setting. Swedish Health Registers. Population. All pregnant women (n = 848,468) and all infants born (n = 861,989)
Informationsdelning - riskfullt, kostsamt eller värdefullt?
Informationsdelning mellan företag sker dagligen. För att optimera logistiken i försörjningskedjan utbyter företag alltifrån orderstatus och lagernivåer till produktionsplaner och tillväxtstrategier. Men är det lika enkelt som det låter? Vilken information bör företag egentligen dela för att förbättra sin logistik och därigenom öka effektivitet och minska kostnader?
Scientific knowledge dynamics and relatedness in biotech cities
This paper investigates the impact of scientific relatedness on knowledge dynamics in biotech at the city level during the period 1989-2008. We assess the extent to which the emergence of new research topics and the disappearance of existing topics in cities are dependent on their degree of scientific relatedness with existing topics in those cities. We make use of the rise and fall of title words
Upphandling och konkurrenskraft : En utvärdering av potentialen för innovationsupphandling med inriktning mot systemlösningar inom energi- och miljöområdet
Bacterial and fungal colonization and decomposition of submerged plant litter: consequences for biogenic silica dissolution.
We studied bacterial and fungal colonization of submerged plant litter, using a known Si-accumulator (Equisetum arvense), in experimental microcosms during one month. We specifically addressed the microbial decomposer role concerning biogenic silica (bSiO2) dissolution from the degrading litter. To vary the rates and level of microbial colonization, the litter was combined with a range of mineral
Inferior Overall Survival In Cll Patients With Tp53 Mutations And Mdm2 Snp309 Polymorphism
An Improved Divergence Information Criterion for the Determination of the Order of an AR Process
In this article we propose a modification of the recently introduced divergence information criterion (DIC, Mattheou et al., 2009) for the determination of the order of an autoregressive process and show that it is an asymptotically unbiased estimator of the expected overall discrepancy, a nonnegative quantity that measures the distance between the true unknown model and a fitted approximating mod
Manipulation, Responsibility and Rights
Optical response of wurtzite and zinc blende GaP nanowire arrays
We compare the optical response of wurtzite and zinc blende GaP nanowire arrays for varying geometry of the nanowires. We measure reflectance spectra of the arrays and extract from these measurements the absorption in the nanowires. To support our experimental findings and to allow for more detailed investigations of the optical response of the nanowire arrays than possible in experiments, we perf
Pro- and synbiotics to prevent sepsis in major surgery and severe emergencies.
Septic morbidity associated with advanced surgical and medical treatments is unacceptably high, and so is the incidence of complications occurring in connection with acute emergencies such as severe trauma and severe acute pancreatitis. Only considering the US, it will annually affect approximately (app) 300 million (mill) of a population of almost one million inhabitants and cause the death of mo
Directed evolution of chemotaxis inhibitory protein of Staphylococcus aureus generates biologically functional variants with reduced interaction with human antibodies
Chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) is a protein that binds and blocks the C5a receptor (C5aR) and formylated peptide receptor, thereby inhibiting the immune cell recruitment associated with inflammation. If CHIPS was less reactive with existing human antibodies, it would be a promising anti-inflammatory drug candidate. Therefore, we applied directed evolution and comput
Pseudomonas aeruginosa CRASP-2 is a surface protein that uses the human terminal complement regulator vitronectin for protection against complement-mediated attack
Multi-component stable isotope records from Late Weichselian and early Holocene lake sediments at Imiolki, Poland: palaeoclimatic and methodological implications
Late Weichselian and early Holocene climatic and environmental changes are inferred from stable carbon and oxygen isotope records obtained on bulk and biogenic carbonates from the sediment sequence of Lake Lednica, western Poland. Along with sediment and pollen stratigraphic data, a wide range of carbonate components occurring in the sediments was analysed for delta C-13 and delta O-18, including
Theme issue "Quality, scale and analysis aspects of urban city models"
Prescribing, Recording, and Reporting External Beam Therapy a Summary of ICRU Reports Nos 29, 50, 62 and 71
This presentation is a summary and a discussion of the ICRU Reports Nos 29, 50, 62 and 71.
Situating Norms and Jointness of Social Interaction
The paper argues that contexts of interaction are structured in a way that coordinates part actions into normatively guided joint action without agents having common knowledge or mutual beliefs about intentions, beliefs, or commitments to part actions. The argument shows earlier analyses of joint action to be fundamentally flawed because they have not taken contextual influences on joint action pr