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Plasma levels of parathyroid hormone were determined pre-operatively in 27 consecutive patients with clinical and biochemical signs of primary hyperparathyroidism, by the use of one assay recognizing the intact PTH molecule and one assay recognizing the mid-portion of PTH. Plasma levels of mid-molecule PTH were normal in 5 of the patients with primary hyperparathyroidism. In 4 of these patients, p
For preoperative localization of enlarged parathyroid glands, several imaging techniques have been used. In this study we demonstrate the feasibility of using ultrasonography with fine needle aspiration for parathyroid hormone assay as a preoperative localization procedure in 21 patients with primary hyperparathyroidism. A single adenoma was found in 18 patients while 3 patients had multiglandular
We examined the use of an intact parathyroid hormone two-site immunoradiometric assay compared with a mid region parathyroid hormone radioimmunoassay in ethylene diamine tetraacetic acid-infusion test in 15 patients with hyperparathyroidism. During the test, plasma intact parathyroid hormone levels increased by 240 +/- 43%, whereas the plasma levels of mid molecule parathyroid hormone increased by
One of the aims of PhD students’ socialisation is for them to accept the norms of the teaching culture and to be fully engaged with and accepted by the university teaching community. However, when PhD students enter universities, they do not necessarily accept all of the university teaching community’s cultural norms, nor do they all experience acceptance by the community. This phenomenographic st
The microscopic observation of lung tissue is challenging due to its fragile nature. Xylene and isopropanol are common tissue-clearing reagents used before paraffin embedding, yet no studies have compared these two reagents in lung tissue processing. Due to the well-known health risks xylene could introduce to operators, as well as its environmental hazards, it has long been desired that a less ha
BACKGROUND AND AIMS: Identifying the haemodynamic mechanism of autonomic syncope is the essential pre-requisite for effective and personalized therapy aimed at preventing recurrences. The present study assessed the diagnostic efficacy of a two-step assessment.METHODS: Multicentre prospective, cross-sectional, observational study. Patients affected by severe autonomic syncope underwent a two-step a
Current genetic research on obsessive-compulsive disorder (OCD) supports contributions to risk specifically from common single nucleotide variants (SNVs), along with rare coding SNVs and small insertion-deletions (indels). The contribution to OCD risk from rare copy number variants (CNVs), however, has not been formally assessed at a similar scale. Here we describe an analysis of rare CNVs called
Despite the availability of new drugs on the clinics in recent years, drug-resistant epilepsy remains an unresolved challenge for healthcare, and one-third of epilepsy patients remain refractory to anti-seizure medications. Gene therapy in experimental models has emerged as effective treatment targeting specific neuronal populations in the epileptogenic focus. When combined with an external chemic
Intrinsic luminescence in Ce-doped (Lu,Y)2SiO5 (or LYSO:Ce) single crystals have been studied by means of excitation luminescence spectroscopy in the vacuum ultraviolet energy range under synchrotron radiation. A previously unreported luminescence band with emission at 250 nm has been discovered as well as its thermal behavior was described in the temperature range 10–120 K. The excitation spectra
Background/Objectives: Recent decades have witnessed a sharp increase in research investigating the association between hearing loss and cognitive impairment. Few previous studies have stratified for sex when investigating this issue, where results were inconsistent and require further clarification. Thus, the objective was to investigate the association between self-reported hearing loss and leve
Multiplanetary systems spanning the radius valley are ideal testing grounds for exploring the different proposed explanations for the observed bimodality in the radius distribution of close-in exoplanets. One such system is HIP 29442 (TOI-469), an evolved K0V star hosting two super-Earths and one sub-Neptune. We observed HIP 29442 with CHEOPS for a total of 9.6 days, which we modelled jointly with
Digital technologies are changing social work practices in profound ways. Today, digital devices are used by social workers in their everyday work; from assessing social benefit applications digitally, writing pre-formatted investigations and using chatrooms in treatment, to holding digital meetings with colleagues and clients. Digital technology is also utilized as a management instrument. Changi
Background: Multicentre studies have previously reported on national outcomes of surgery for primary hyperparathyroidism, but not investigated whether management and outcome are uniform among countries. This study investigated whether there are differences among European countries in operative management and outcome of surgery for primary hyperparathyroidism. Methods: Using data from Eurocrine®, a
The EU’s Common Agricultural Policy (CAP) has been broadened over recent decades in response to evolving challenges faced by the EU and its farmers. It now claims to support not only food security and farmers’ incomes, but also transitioning to a green economy, conservation of biodiversity and climate action. We have evaluated to what extent four main types of CAP payment instruments form a cohesi
The aim of the project is to investigate the possibility of using people's mobile phones to locate people in a tunnel environment using the mobile phone's Wi-Fi connection. In total, 39 different trials were carried out under different conditions in a road tunnel in Stockholm, Sweden. In the trials, the Wi-Fi-based predicted location has been compared with the actual location of the recruited 16 p
Objectives The study aimed to describe the experiences of physicians, nurses and psychologists employed in primary care in using digital video consultations. The second objective was to study the association between the predictors of behaviour and behavioural intentions to use digital consultations and to relate underlying behavioural beliefs to experiences of digital consultations in primary care
Objectives To develop a protocol for largescale analysis of synovial fluid proteins, for the identification of biological networks associated with subtypes of osteoarthritis. Methods Synovial Fluid To detect molecular Endotypes by Unbiased Proteomics in Osteoarthritis (STEpUP OA) is an international consortium utilising clinical data (capturing pain, radiographic severity and demographic features)
Transport in open quantum systems can be explored through various theoretical frameworks, including the quantum master equation, scattering matrix, and Heisenberg equation of motion. The choice of framework depends on factors such as the presence of interactions, the coupling strength between the system and environment, and whether the focus is on steady-state or transient regimes. Existing litera
