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Background Both internet-based cognitive-behavioural therapy (ICBT) and physical exercise are alternatives to treatment as usual (TAU) in managing mild to moderate depression in primary care.Aims To determine the cost-effectiveness of ICBT and physical exercise compared with TAU in primary care.Method Economic evaluation of a randomised controlled trial (N = 945) in Sweden. Costs were estimated by

PURPOSE: To estimate cause-specific mortality in osteoarthritis patients compared to the general population.METHODS: We identified all residents in southern Sweden aged 45-84 years in 2003. Through the Skåne Healthcare Register we identified those diagnosed with osteoarthritis in peripheral joints between 1998-2003. We followed all residents from 2004 until relocation outside of the region, death,

While there is a huge literature on exchange rate systems since the classical gold standard, less research has been devoted to comparisons of the different arguments that guided the choices. While the origin of the international gold standard in the 1870s was a result of silver coins disappearing from circulation due to rising silver prices, the gold standard has later been interpreted as a quest

Galectin-3 is a carbohydrate binding protein which has important roles in cancer and immunity. Potent galectin-3 inhibitors have been synthesized, for experimental purposes and potential clinical use. As galectin-3 is implicated in both intra- and extracellular activities, permeability of galectin-3 inhibitors is an important parameter determining biological effects. We compared the cellular uptak

Invasive extravillous cytotrophoblast of the human placenta expresses galectins-1, -3, and -8 in vivo and in vitro. This study aimed to investigate the potential role of galectin-3 in cell migration and invasion, using recombinant human galectin-3 (rhgalectin-3), small molecule galectin inhibitor I 47 , and galectin-3 silencing. HTR-8/SVneo cell migration was stimulated by rhgalectin-3 and reduce

Application of the Luttinger theorem to the Kondo lattice YbRh 2 Si 2 suggests that its large 4f-derived Fermi surface (FS) in the paramagnetic (PM) regime should be similar in shape and volume to that of the divalent local-moment antiferromagnet (AFM) EuRh 2 Si 2 in its PM regime. Here we show by angle-resolved photoemission spectroscopy that paramagnetic EuRh 2 Si 2 has a large FS essenti

There is a growing evidence of the protective role of the Mediterranean diet (MD) on cancer. However, no prospective study has yet investigated its influence on lymphoma. We evaluated the association between adherence to the MD and risk of lymphoma and its subtypes in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The analysis included 476,160 participants, recruite

The present paper investigates the fluid flow and heat transfer behaviors of jet impingement in cross-flow modified by a vortex generator pair (VGP). The velocity of the jet is kept at 12 m/s and that of the cross-flow is varied between 5 m/s and 8 m/s. The spacing between the jet and target surface is 4 times the jet diameter. Particle Image Velocimetry (PIV) and Liquid Crystal Thermography (LCT)

Phased array antennas are cornerstones in many proposed antenna solutions concerning the next generation of both airborne radar systems and wireless communication systems (5G). Additionally, millimeter wave (mm-wave) frequencies are expected to play an integral role in 5G, and are deemed well-suited for inspecting structural components used in the aerospace industry.This dissertation consists of a

The effect of sub-monolayer silicon on the oxidation of Al(111) and Al(100) surfaces was investigated using X-ray Photoelectron Spectroscopy (XPS) and density functional theory (DFT) calculations. On both surfaces the adatom site is preferred over substituting Si into the Al-lattice; on Al(100) the four fold hollow site is vastly favored whereas on Al(111) bridge and hollow sites are almost equal

Cross laminated timber (CLT) at in-plane beam loading conditions presents a complex stress state wherefore several failure modes and geometry parameters need to be considered in design. The work presented here includes experimental investigations of CLT beams for comparison and validation of an analytical model and design proposals previously suggested by the authors. All relevant failure modes ar

The relationship between pesticides and pollinators, while attracting no shortage of attention from scientists, regulators, and the public, has proven resistant to scientific synthesis and fractious in matters of policy and public opinion. This is in part because the issue has been approached in a compartmentalized and intradisciplinary way, such that evaluations of organismal pesticide effects re

The optimal mode of delivery for a pregnant hemophilia carrier is still a matter of debate. The aim of the study was to determine the incidence of intracranial hemorrhage and other major bleeds in neonates with moderate and severe hemophilia in relationship to mode of delivery and known family history. A total of 926 neonates, 786 with severe and 140 with moderate hemophilia were included in this

Effective measurement of exposure to air pollution, not least NO2, for epidemiological studies along with the need to better management and control of air pollution in urban areas ask for precise interpolation and determination of the concentration of pollutants in nonmonitored spots. A variety of approaches have been developed and used. This paper aims to propose, develop, and test a spatial pred

During the transition from the last glacial into the Holocene interglacial, the atmospheric circulation in the North Atlantic area changed from a glacial mode, influenced by the presence of large ice sheets, into a system more similar to that of the present day. This change had implications for wind, temperature and precipitation patterns that can be traced in geological archives. Here, we focus o

The plastic carrier bag epitomises many of the features that have transformed plastics into a material that defines our contemporary modern culture. The versatility, durability, strength and low cost have made it into an indispensable companion for consumers. In parallel with plastic becoming an increasingly contested material, the plastic carrier bag has emerged as a controversial object in many

Rapidly developing technology and an increasing number of products containing electrical or electronic functions, has led to discarded electrical and electronic equipment (EEE) being one of the fastest growing waste streams. The European Union (EU) has enacted several iterations of the Waste Electrical and Electronic Equipment (WEEE) Directive to address this complex waste stream. However, recycli

The measurement of pressure using laser-induced thermal grating spectroscopy, LITGS, with improved accuracy and precision is reported. Pressure values are derived from the record of the time-profile of LITGS signals by fitting of modelled signals to experimental data. The procedure is described for accurate modelling of the LIGS signals involving a sequence of calculation steps with appropriate w