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A series of 3-triazole-thiogalactosides and 3,3′-triazole-thiodigalactosides substituted with different five-membered heterocycles at the C-4 triazole position were found to have high selectivity for galectin-1. Initial studies on the 3-triazole-thiogalactosides indicated that five membered heterocycles in general gave increased affinity for galectin-1 and improved selectivity over galectin-3. The
Living labs for sustainability, low carbon and smart cities that have emerged in Europe have different goals and ways of working, they are initiated by various actors, and they form different types of partnerships. There is clearly no uniform definition of living labs. Some scholars and organisations define them as partnerships between sectors (often between public, private and people) where unive
Industrial processes currently account for a significant share (25–35 %) of the world’s total energy demand and related emis- sions. During recent years, the amount of low-carbon electric- ity from renewable energy sources (such as wind and solar) has increased continuously. There is therefore an increasing inter- est in electrification of industrial processes in order to achieve long-term decarboIndustrial processes currently account for a signifcant share (25–35 %) of the world’s total energy demand and related emissions. During recent years, the amount of low-carbon electricity from renewable energy sources (such as wind and solar) has increased continuously. Tere is therefore an increasing interestin electrifcation of industrial processes in order to achieve long-term decarbonisation g
All cities face a pressing challenge - how can they provide economic prosperity and social cohesion while achieving environmental sustainability? In response, new collaborations are emerging in the form of “urban living labs” (ULL) - sites devised to design, test and learn from social and technical innovation in real time. ULL are proliferating rapidly across cities internationally as one means th
This book has sought to advance the theorisation of the interface between experimentation, socio-technical transitions and the city, through an internationally comparative empirical analysis of ULL. This has been structured through three core elements. First, through a set of conceptually informed empirical case studies from Africa, Asia, Europe and North America, based on original empirical work
All cities face a pressing challenge - how can they provide economic prosperity and social cohesion while achieving environmental sustainability? In response, new collaborations are emerging in the form of urban living labs - sites devised to design, test and learn from social and technical innovation in real time. The aim of this volume is to examine, inform and advance the governance of sustaina
Urban experimentation has gained traction in cities all over the world as a way to find new, more sustainable ways to plan and develop cities. Interventions designed to address a diverse range of urban challenges bring innovative social and technical components together to learn by doing. Seen through this lens, the modernist planning that dominated the urban arena for much of the twentieth centur
Extracting microanatomical information beyond the image resolution of MRI would provide valuable tools for diagnostics and neuroscientific research. A number of mathematical models already suggest microstructural interpretations of diffusion MRI (dMRI) data. Examples of such microstructural features could be cell bodies and neurites, e.g. the axon's diameter or their orientational distribution for
Objectives: The aim is to estimate agreement between two-dimensional transvaginal ultrasound (2D-TVS) and three-dimensional volume contrast imaging (3D-VCI) in diagnosing deep myometrial invasion (MI) and cervical stromal involvement (CSI) of endometrial cancer and to compare the two methods regarding inter-rater reliability and diagnostic accuracy. Methods: Fifteen ultrasound experts assessed off
This report summaries knowledge concerning the impact of the maintenance of bicycle and pedestrian infrastructure. The aim of the literature review was to compile existing knowledge on operation and maintenance of the transport infrastructure for pedestrians and cyclists, the highlight how operation andmaintenance affect pedestrians and cyclists, in terms of accessibility, safety and security. TheThis report summarises knowledge concerning the impact of the maintenance of bicycle and pedestrianinfrastructure. The aim of the literature review was to compile existing knowledge on operation andmaintenance of the transport infrastructure for pedestrians and cyclists, the highlight how operation andmaintenance affect pedestrians and cyclists, in terms of accessibility, safety and security. The
As urban areas expand rapidly worldwide, wildlife is exposed to a wide range of novel environmental stressors, such as increased air pollution and artificial light at night. Birds in highly polluted and/or urbanized habitats have been found to have increased antioxidant protection, which is likely important to avoid accumulation of oxidative damage, which can have negative fitness consequences. YeAs urban areas expand rapidly worldwide, wildlife is exposed to a wide range of novel environmental stressors, such as increased air pollution and artificial light at night. Birds in highly polluted and/or urbanized habitats have been found to have increased antioxidant protection, which is likely important to avoid accumulation of oxidative damage, which can have negative fitness consequences. Ye
When the story of Scandinavian literature is being told in an international context, the Swedish proletarian novels of the 1930s are frequently held up as the more important of the regional canon. 1 In these celebrated novels, childhood and children are at the center-so much so, that I would suggest that the child is one of the more prominent motifs of Swedish literature between the two World Wars
