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This study examined the role of a daytime nap in the consolidation and generalization of fear learning. 31 healthy, young adult participants (16 in the wake group and 15 in the sleep group) underwent a fear acquisition procedure in which the conditioned stimulus (CS+), a composite image consisting of a geometrical figure imposed on a background, was repeatedly paired with a mild electric shock. Th
Polystyrene micro- and nanoplastics (PS-MNPs) are emerging environmental pollutants with potential implications for human health. This study investigated the cytotoxic effects of PS particles by using two different sizes of PS-MNPs (0.25 µm and 1 µm) on non-small cell lung cancer (A549, H460), small cell lung cancer (DMS53, H372), and normal lung epithelial (BEAS-2B) cells as well as on human-deri
This article explores how public transportation workers and passengers conceptually can be brought together. This is well worth discussing because of how these two positions are interconnected and simultaneously impacted by how public transportation is organized and operated. This applies to for example increased efficiency measures and digitalization, possibly well received by some passengers whi
This dataset presents a comprehensive collection of microscopic images, infrared (IR) spectra of particles obtained from beach sediment in Tioman Island, Malaysia. Sediment samples were collected from multiple sites across three selected beaches to identify material composition and assess the concentration of plastic particles, including both microplastics (<5 mm) and macroplastics (>5 mm), in the
A complication in the treatment of any strongly charged particle is the SU(3) color structure. For the standard model quarks, antiquarks and gluons there are various well-known strategies for dealing with the color structure, including orthogonal multiplet bases. For exotic representations, beyond triplets, antitriplets and octets, non-orthogonal bases have been systematically worked out only rece
Background: Colorectal cancer (CRC) is shaped by a complex tumor immune microenvironment in which inflammatory mediators like cyclooxygenase-2 (COX-2) and immune checkpoints such as programmed cell death ligand 1 (PD-L1) play central regulatory roles. However, the prognostic significance of these makers, individually and in combination with T-cell infiltration, remains poorly defined.Methods: We i
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: Primary objective To evaluate the benefits and harms of intratracheal instillation of corticosteroids combined with surfactant versus surfactant alone for the preventing chronic lung disease in preterm infants. Secondary objective To identify equity issues that may be associated with the implementation, uptake,
Background: Psychological resilience refers to a person's positive adaptation when faced with adversities, such as a breast cancer (BC) diagnosis. Highly resilient patients are more likely to regain stability and be protected from health conditions such as depression, anxiety, and posttraumatic stress disorder. We aimed to identify epigenetic markers that distinguish high- and low-resilient patien
Geomagnetic field models constrained by direct observations extend back some 400 years and the magnitude of decadal to centennial variations that they display is often assumed to be typical of the secular variation over longer timescales. Here we present archaeomagnetic directions from layered Neolithic hearths in Orkney, dating to around 3000 BCE, that challenge this assumption. Combining stratig
Each year as the seasons turn, the skies fill with millions of travellers. From the tundra to the tropics, birds embark on remarkable journeys guided by an innate programme and perform one of nature’s most remarkable phenomena: migration. In this thesis, I tackle the study of the genetic basis of migratory behaviour in several Phylloscopus species with a multimodal approach. Here, I combine geoloc
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy, yet clinical tools for diagnosis, prognosis, and treatment remain limited, and molecular profiling of histotypes is lacking. Here, we leverage proteomic data to further stratify four main EOC histotypes, borderline (BL) and benign (B) tumors, and identify candidate prognostic and diagnostic biomarkers. Using proteomic data
Hair analysis has been used in the past as a method to explore environmental exposure to chemicals, toxins or drug ingestion, with wide applications in forensic science, environmental studies, anthropology and medicine. Although not a conventional sample type, hair offers significant advantages over traditional biospecimens, such as blood or urine. These include its stability, non-invasive nature
Introduction: This study focused on characterizing the phase transition behavior in water of thermoresponsive cationic diblock copolymers comprised of a cationic and a non-ionic block. Background: Thermoresponsive polymers, especially block copolymers, have long been of interest to researchers within the field of drug delivery systems. However, more research into their phase transition behavior i
Purpose: The sugar industry is always pressured to be suitable and enhance its operational effectiveness. Digital Twin (DT) has the potential to transform this industry. However, the lack of industry-specific Key Performance Indicator (KPI) frameworks makes it challenging to implement them. This study provides a hierarchical KPI model for DT adoption in the sugar sector, interconnecting the United
PurposeIn the age of digital businesses, the rise of innovative digital transformation has made supply chain transparency (SCT) an essential research topic. While digital technologies provide possibilities for enhancing transparency in supply chains, there is limited research on how digital businesses overcome different SCT issues or provide real-time visibility and traceability. This study aims t
Connections between proof complexity and circuit complexity have become major tools for obtaining lower bounds in both areas. These connections – which take the form of interpolation theorems and query-to-communication lifting theorems – translate efficient proofs into small circuits, and vice versa, allowing tools from one area to be applied to the other. Recently, the theory of TFNP has emerged
