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Role of adhesion molecules and chemokines in TNF-alpha-induced leukocyte recruitment

Popular Abstract in Swedish Svensk sammanfattning Inflammation är kroppens svar på yttre störning. Det inflammatoriska svaret är nödvändigt för att bekämpa infektioner, t.ex. med bakterier. Å andra sidan orskar det inflammatoriska svaret mycket skada när det aktiveras utan närvaro av infektioner, tex vid astma, reumatism, blodförgiftning och inflammatorisk tarmsjukdom. Akut inflammation karaktäriMigration of leukocytes from the circulating blood into the extravascular tissue is a key component in inflammatory reactions. Leukocyte extravasation (rolling-activation-adhesion-transmigration) is strictly coordinated by adhesion molecules and chemokines expressed on cell surfaces and in tissues. Tumor necrosis factor-alpha (TNF-alpha) is pleiotrophic cytokine, which plays an important role in t

Unruhe und Ungewissheit – Stem Cells and Risks

“Die Unruhe und Ungewissheit sind unser Theil”, writes Goethe in a letter to the German novelist Sophie von la Roche in 1774. But is it the incalculable and indeterminate that cause disquiet, or is it our bustling pursuit of knowledge that makes us uncertain? Contemporary psychologists have taught us a great deal about the way we perceive risks and about the way affects and emotions influence our

Optimal Control of a Fully Decentralized Quadratic Regulator

In this paper, we consider a fully decentralized control problem with two dynamically decoupled agents. The objective is to design a state-feedback controller for each agent such that a global quadratic cost is minimized. No communication, explicit or implicit, is permitted between the agents. However, the performance of the agents is coupled via the cost function as well as the process noise. We

I väntan på asyl. Retorik och praktik i svensk flyktingpolitik.

Popular Abstract in Swedish I min forskning undersöker jag hur lagar och regler om asyl översätts till praktik i handläggningen av asylärenden i Sverige. Mina utgångspunkter är samhällets organisation av asylprövningen och strukturerna i denna organisation. I avhandlingen finns en redogörelse för ett enskilt fall. I detta fall finns en mängd av de olika problem som uppstår i asylärenden representeThe purpose of my research is to examine the translation of logos into praxis in the handling of asylum-cases in Sweden. My point of departure has been the manner in which society has organised the handling of asylum-cases and the structure of this organisation. My thesis contains an account of an individual case which is representative of a multitude of problems in the asylum case handling. Casew