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Neutrophil extracellular traps (NETs) are involved in acute pancreatitis (AP) but mechanisms controlling NET expulsion in AP are incompletely understood. Herein, we examined the role of c-Abelson (c-Abl) kinase in NET formation and tissue damage in severe AP. AP was induced by taurocholate infusion into pancreatic duct or intraperitoneal administration of l-arginine in mice. Pancreatic, lung, and
Alpha-1-antitrypsin deficiency (AATD) is a hereditary disorder. AATD is a known risk factor for the development of emphysema and liver disease. A cohort of severe (PiZZ) and moderate (PiSZ) AAT-deficient newborn infants was identified by the Swedish national neonatal AAT screening in 1972-1974 and has been followed up since birth. Our aim was to study survival in this cohort up to 43-45 years of a
Purpose: Speech signal degradation such as a voice disorder presented in quiet or in combination with multi-talker babble noise could affect listening comprehension in children with hearing impairment. This study aims to investigate the effects of voice quality and multi-talker babble noise on passage comprehension in children with using cochlear implants (CIs) and/or hearing aids (HAs). It also a
This article analyzes vocals-only Islamic pop music as a musical genre and mode of production. The aim is to present and discuss this particular form in relation both to its history as an Islamic phenomenon and, more broadly, to consumer society aesthetics. The article focuses on songs from the Islamic media company Awakening and its highly successful output of Islamic pop music, sketching the gen
The effects of hydroethanolic extract of Yacon leaves (HEYL) on antioxidant, glycemic, and inflammatory biomarkers were tested in diabetic rats. Outcome parameters included glucose, insulin, interleukin-6 (IL-6), and hydrophilic antioxidant capacity (HAC) in serum and IL-6, HAC, malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in soleus. The rats
Planktonic community respiration is an important carbon cycling process, typically quantified by converting measured values of dissolved O 2 consumption rates into CO 2
Hawkmoths (Lepidoptera, Sphingidae) comprise around 1500 species, most of which forage on nectar from flowers in their adult stage, usually while hovering in front of the flower. The majority of species have a nocturnal lifestyle and are important nocturnal pollinators, but some species have turned to a diurnal lifestyle. Hawkmoths use visu
Obesity is considered an important risk factor for several disorders, such as diabetes mellitus, systemic arterial hypertension, dyslipidemia, and atherosclerosis, which are associated with inflammation and oxidative stress as a trigger factor. Passiflora edulis contains important bioactive compounds, such as phenolics, carotenoids, vitamin C, and polyamines in pulp, leaves, seeds, and bark. Aim:
The Carrot psyllid, Trioza apicalis Förster (Homoptera: Psylloidea: Triozidae) is one of the major insect pests of carrots (Daucus carota L.) in parts of northern and central Europe. Gas chromatography–single-sensillum recording (GC–SSR) previously confirmed several active compounds in a carrot leaf extract, but the most active compound rem
Resveratrol (RSV), polyphenol from grape, was studied to evaluate its effects on calorimetric parameters, energy metabolism, and antioxidants in the myocardium of diabetic rats. The animals were randomly divided into four groups (n = 8): C (control group): normal rats; C-RSV: normal rats receiving RSV; DM: diabetic rats; and DM-RSV: diabetics rats receiving RSV. Type 1 diabetes mellitus was induce
Under the Paris Agreement, nations have committed to preventing dangerous global warming. Scenarios for achieving net-zero emissions in the second half of this century depend on land (forests and bioenergy) to remove carbon from the atmosphere. Modelled levels of land-based mitigation could reduce the availability of productive agricultural land, and encroach on natural land, with potentially sign
Ecosystem services inherently involve people, whose values help define the benefits of nature's services. It is thus important for researchers to involve stakeholders in ecosystem services research. However, a simple and practicable framework to guide such engagement, and in particular to help researchers anticipate and consider key issues and challenges, has not been well explored. Here, we use e
The effects of the inhalation of Cymbopogon martinii essential oil (EO) and geraniol on Wistar rats were evaluated for biochemical parameters and hepatic oxidative stress. Wistar rats were divided into three groups n = 8: G1 was control group, treated with saline solution; G2 received geraniol; and G3 received C. martinii EO by inhalation during 30 days. No significant differences were observed in
AIM: To investigate the effects of fructose consumption on the antioxidant capacity in heart and kidney, cardiovascular disease risk factors, and evaluation of these variables after its removal.METHODS: Male Wistar rats (n = 36) were divided into control group (n = 12): standard chow + water or F group: standard chow + fructose in drinking water (30%) for 15 weeks. After, F group was divided to co
Caloric restriction, defined as a reduction in calorie intake below ad libitum, without malnutrition can have beneficial effects. In this study, we evaluated the impact of caloric restriction of 30 and 60% on calorimetric parameters and oxidative stress in cardiac tissue in rats. Rats were randomly divided into 3 groups (n = 8): G1 = control; G2 = rats exposed to dietary restriction of 30%; and G3
The kidney is an important organ in the maintenance of body homeostasis. Dietary compounds, reactive metabolites, obesity, and metabolic syndrome (MetS) can affect renal filtration and whole body homeostasis, increasing the risk of chronic kidney disease (CKD) development. Gamma oryzanol (γOz) is a compound with antioxidant and anti-inflammatory activity that has shown a positive action in the tre
A model for strategic communication management was developed in South Africa on the basis of the excellence study and relationship management theories. This normative, theoretical model has been applied as part of a project in non-profit organisations (NPOs), government institutions and small-to-medium sized companies. However, the operational reality of organisations’ communication practices has
Francois Bloemhof submitted his novel for teenagers, “Slinger-slinger” for the Sanlam competition for youth fiction in 1996. Eventually this prizewinner in the beginners’ category was published in 1997. The main theme of “Slinger-slinger” is the sexual awakening and identity of teenagers.A study was undertaken to obtain the opinions of teenage readers about the success of “Slinger-slinger” as a wh
Critical infrastructures provide society with services essential to its functioning, and extensive disruptions give rise to large societal consequences. Risk and vulnerability analyses of critical infrastructures generally focus narrowly on the infrastructure of interest and describe the consequences as nonsupplied commodities or the cost of unsupplied commodities; they rarely holistically conside
The Steyn and Puth (2000) model for strategic communication management has been applied by students and other project participants to non-profit organisations (NPOs), government institutions and small and medium enterprises in South Africa, but organisations’ communication practices have not been measured against the model. This paper reports on the strategic communication management practices of
