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Läkares utbildning har tre faser med skilda uppdrag och ansvar – från grundutbildning och vidareutbildning till specialistutbildning och sedan fortbildning. Grundutbildningen, men även vidareutbildningen, har ett särskilt ansvar för kompetensförsörjning baserat på hälso- och sjukvårdens långsiktiga behov, nationellt och internationellt [1]. Det förutsätter en analys av de arbetsuppgifter som läkar

© 2017 Metal cutting simulations have become an important part of cutting tool design and the research in the field in general. One of the most important aspects of modeling is the accuracy of the tool geometry. 3D microscopy is used for measuring the tool edge radius with good accuracy. However, especially with sharp tools, i.e. small tool edge radii, the measurements, no matter how accurate, are

The goal of metal cutting research is to predict process conditions accurately with a model or a simulation, in order to optimize and develop the processes. Development of such a model requires understanding of multiple branches of physics and engineering such as continuum mechanics, thermodynamics, tribology and materials science. For an accurate model, each aspect of the process must be modelled

© 2018 Elsevier Ltd Electrical steel is used for the active parts in electrical machinery that form the magnetic circuits because the material experiences low iron loss, and thus, has superior magnetizing properties. A typical electrical sheet has a thickness of 0.5 mm and is punched into its final shape via a piercing process. Piercing causes large deformations and residual stresses in the narrow

A low-molecular-weight heparin (LMWH), Tinzaparin, was compared with unfractionated heparin (UFH) for their effects on platelet aggregation in vitro and ex vivo. Both heparins showed a dose-dependent proaggregatory effect on ADP- and collagen-induced platelet aggregation in vitro, but LMWH was less potent. The differences in potency between Tinzaparin and UFH depended on how the compounds were com

Mitochondrial open reading frame of the 12S rRNA-c (MOTS-c) is a mitochondrial-derived peptide that attenuates weight gain and hyperinsulinemia when administered to high fat-fed mice. MOTS-c is therefore a potential regulator of metabolic homeostasis under conditions of high-energy supply. However, the effect of insulin resistance and obesity on plasma MOTS-c concentration in humans is unknown. To

The aim of the present study was to investigate whether tinzaparin sodium (a low-molecular-weight heparin (LMWH)) was fully and permanently neutralized in vivo in man by protamine sulphate (PS) after intravenous (i.v.) or subcutaneous (s.c.) injection. Fifty healthy adults equally divided in five age- and sex-matched groups were included. The groups received 50 IU unfractionated heparin (UH)/kg bo

The aim was to investigate whether a truncated recombinant Tissue Factor Pathway Inhibitor (TFPI1-161) which lacked the third Kunitz-type domain and the basic c-terminal region, had an antithrombotic effect comparable to LMWH in a randomised double-dummy study. The experimental thrombosis was induced in jugular veins, in a total of 40 rabbits by a combination of destruction of the endothelium and

AIM: This study investigated time trend and regional disparities in hospitalisations due to osteoarthritis (OA) among people aged ≥20 years in Sweden from 1998 through 2015.METHODS: National and regional data on hospital admissions with a primary diagnosis of OA were collected from the National Patient Register. The absolute and relative regional disparities were assessed using the absolute weight

Integrated development environments have provided increasingly powerful tools for software creation, and yet the creation of complex computer programs remains difficult and time-consuming. Liveness in a programming environment has been identified as one direction in which to pursue further improvements in programmer productivity. We propose a scheme for achieving strategically predictive liveness, t