Search results

AIMS: To evaluate the long-term clinical and economic outcomes associated with insulin detemir and neutral protamine hagedorn (NPH) insulin in combination with mealtime insulin aspart in patients with type 1 diabetes in Sweden, based on data from a two-year, multi-national, open-label, randomized, controlled trial.METHODS: Insulin detemir was associated with significant improvements in glycaemic c

Electric road systems (ERSs) present a transformative advancement in transportation electrification, offering continuous charging capabilities for electric vehicles (EVs) during travel. This innovation has the potential to significantly mitigate range anxiety by enabling in-motion charging, thereby enhancing the overall efficiency of electric mobility, and reducing the frequency of charging stops

De senaste åren har den digitaliserade ekonomin etablerats i Sverige. En del av utvecklingen är plattformsarbete eller gig-jobb, som innebär att korta uppdrag åt flera uppdragsgivare förmedlas via en digital delningsplattform eller app. Rättsreglerna är uppbyggda binärt, vilket förenklat innebär att det finns två möjliga system: det ena gäller för dem som är arbetstagare och det andra för dem som

Different types of information are combined during variation interpretation. Computational predictors, most often pathogenicity predictors, provide one type of information for this purpose. These tools are based on various kinds of algorithms. Although the American College of Genetics and the Association for Molecular Pathology guidelines classify variants into five categories, practically all pat

Purpose: This study aimed to assess the relationship between regional body composition and metabolic dysfunction-associated fatty liver disease (MAFLD) in Chinese children.Methods: In this study, 1399 children aged 7–14 years were included. Liver steatosis was assessed using the controlled attenuation parameter (CAP) measured through Fibroscan. MAFLD is defined as the presence of liver steatosis a

Background/Objectives: The surgeon’s subjective intraoperative evaluation is the standard of care to assess postoperative residual disease (RD) in advanced epithelial ovarian cancer (EOC). We investigated the feasibility of ctDNA as an objective marker for postoperative RD. Methods: This prospective study included 27 patients with advanced ovarian cancer (FIGO IIIA1–IVB) who underwent primary surg

Compacted graphite iron (CGI) is an intermediate material between conventional grey cast iron and the stronger, more wear resistant ductile iron, making it a suitable material choice for different automotive applications. The improved material properties of CGI as to conventional grey cast iron makes it more difficult to machine, and finding a suitable tool material with low wear rates is a challe

The disruption of microtubule dynamics serves as a pivotal strategy for eliminating tumor cells, despite its accompanying toxicities affecting non-tumor cells. This study investigates the potential of selectively targeting γ-tubulin1 (TUBG1) as a therapeutic strategy in cancer treatment. By elucidating the TUBG1-E2F1-retinoblastoma protein (RB1) network, we introduce a novel compound, 4-(6-((3-Met

The chapter focuses on how process is reviewed in the general framework of EU legal analysis applicable to national pre-authorisation schemes. By examining the model of judicial review developed by the Court of Justice in this regard, I hope to enrich the discussion on what process federalism within the Union can look like and how it may function. After some brief explanations regarding the charac

BACKGROUND: The increasing longevity of people with intellectual disability creates a need for a healthy-ageing perspective, translated into evidence-based interventions in this multi-morbidity group. Accordingly, the aim of this scoping review was to identify, summarise and analyse the empirical research on healthy ageing in older adults with intellectual disability.METHODS: This review was based

Identifying structural change is a crucial step when analyzing time series and panel data. The longer the time span, the higher the likelihood that the model parameters have changed because of major disruptive events such as the 2007–2008 financial crisis and the 2020 COVID-19 outbreak. Detecting the existence of breaks and dating them is therefore necessary for not only estimation but also unders

Last week, six intrepid retail researchers from the Centre for Retail Research at Lund University travelled to London to observe the latest retail trends. Here, we summarise the most important trends and what the Swedish retail industry can learn from what is happening in London.

Objective: Studies have implied that fibroblasts may act as regulators of immune cells in the tumor microenvironment (TME). We investigated the clinical relevance of fibroblast activation protein (FAP) positive stroma in high-grade serous ovarian cancer (HGSC) in relation to CD8+ lymphocyte's infiltration. Methods: In a discovery cohort (N = 113) of HGSC, expression of FAP and CD8 in the TME was a

Expectations of what constitutes a positive customer experience have changed over time. Developments in technology and digital services have enabled new kinds of customer experience. As have new store formats and diversified retail offerings. Regardless of the form it has taken, customer experience has always been of paramount importance to retail managers. And it continues to be so. Over 50% of p

The new retail landscape is complex. New types of touchpoints and new store formats mean messy, non-linear customer journeys with multiple online and offline touchpoints. If we want to understand these journeys, and what value customers derive from new and innovative touchpoints, we must use methods that allow them to explain their own complex customer journeys in all their messy glory!