The outstanding success of structural biology within the last two decades is closely related to the development and evolution of macromolecular crystallography (MX) beamlines. Indeed, many of today's synchrotron-based MX experimental sessions aim for fast but rigorous evaluations and data collections from very large numbers of samples [1–7]. To facilitate this, sample changing on most MX beamlines

We reanalyze the recent multilab preregistered study on ego-depletion by Hagger and Chatzisarantis (2016) as if their data were obtained under the research program-strategy (Witte & Zenker, 2016a, 2016b). This strengthens Hagger and Chatzisarantis’s (2016) main conclusion, because our reanalysis more directly corroborates the absence of a medium-sized, or a small-sized, ego-depletion effect (d

Currently I am studying the realization of two large-scale experimental natural science facilities: The European Spallation Source (ESS) and MAX IV (a synchrotron facility). They are examples of New Big Science (NBS) – facilities where substantial amounts of resources and hopes are tied to making future scientific discoveries. Both facilities will host more than 20 different instruments, catering Feminist technoscience studies (FTS) comprise a major strand of STS. Constituted by a diverse and heterogeneous set of projects and publications, these studies make politicised, impassioned contributions to contemporary critical thought about science, technology and medicine. They are also driven by a powerful desire for justice (see Reardon et al in Catalyst Vol 1 No 1). Building on century-old t

In this paper I will explore two trends that I argue pose significant challenges to feminist technoscience studies as a knowledge-producing endeavour. The first is Sweden democrats’ use of figures as facts, with the hope of changing society into a fascist one. The other is the investment in natural science research infrastructure with the hope of solving societies most pressing problems. Sweden de

Focusing on the Swedish census of 1900, the child-woman ratio and own-children method have been applied to assess socioeconomic differences in fertility. These indirect estimates of fertility have been compared to the vital statistics at the national level to assess their reliability. This comparison demonstrated that the estimated results suffered from few errors. Even if these indirect estimates

In continental margin basins, the hydrogeological setting is complex due to transgression/regression events that removed old sediments in the basin and formed new geologic units. Due to the geological complexity, the use of vertical electrical sounding has proven to be insufficient for groundwater explorations. The lack of understanding the geological underground has resulted in many boreholes wit

In the domain of current spatial semiotics two important, but also radically different, approaches can be distinguished as modelling the co-operative agency of human, material and legal properties of space, namely that of Manar Hammad’s and that of Bruno Latour’s. Hammad, being a semiotician, more true to the Greimasian heritage, regards a finite set of principal actantial types (owners, visitors,

The objective of this study was to develop, test and evaluate a specifically defined interdisciplinary approach—the human-centred approach—as applied to a case study, Iron Age Öland. Four themes were selected to highlight different aspects of particular interest in Öland: taphonomy, diet, migration, and social organization. The uncremated human skeletal remains from Öland are the basis for this st

Dynamic nuclear polarization of (13)C-labeled cell substrates has been shown to massively increase their sensitivity to detection in NMR experiments. The sensitivity gain is sufficiently large that if these polarized molecules are injected intravenously, their spatial distribution and subsequent conversion into other cell metabolites can be imaged. We have used this method to image the conversion

Purpose: Case reports suggest that patients with previous gastric bypass have an increased risk of severe hypocalcemia after total thyroidectomy, but there are no population-based studies. The prevalence of gastric bypass before thyroidectomy and the risk of hypocalcemia after thyroidectomy in patients with previous gastric bypass were investigated. Methods: By cross-linking The Scandinavian Quali

Wheat straw is one of the main agricultural residues of interest for bioethanol production. This work examines conversion of steam-pretreated wheat straw (using SO2 as a catalyst) in a hybrid process consisting of a short enzymatic prehydrolysis step and a subsequent simultaneous saccharification and fermentation (SSF) step with a xylose-fermenting strain of Saccharomyces cerevisiae. A successful

A series of amine adducts of the fungal metabolite galiellalactone (1) were prepared by reacting galiellalactone with different secondary amines via a Lewis acid catalyzed Michael addition. The adducts were assayed for in vitro effects toward prostate cancer cell lines and found to possess a similar ability to inhibit cell proliferation as galiellalactone itself. It was found that the Michael addi

Infection tolerance is the ability of a host to limit the health effects of a given parasite load. A few recent studies have demonstrated genetic variation for tolerance, but little is known about how environmental factors affect tolerance. Here, we used the intestinal nematode Heligmosomoides polygyrus in laboratory mice to test for effects of protein malnutrition on tolerance. We performed an ex

Understanding the mechanisms that govern the combustion processes is important for being able to further increase the efficiency ofcombustion devices. Temperature is considered to be one of the most important parameters controlling the progression and finalproducts of combustion. Regulating the temperature in combustion devices enables higher degrees of efficiency to be achieved. Theengine compone

The aim of this study was to synthesize and characterize a nano-hydroxyapatite (nHAP) and calcium sulfate bone substitute (NC) for cranioplasty. The NC was functionalized with low concentrations of bone morphogenetic protein-2 (BMP-2) and zoledronic acid (ZA) and characterized both in vitro and in vivo. In vitro studies included MTT, ALP assays, and fluorescent staining of Saos-2 (human osteoblast