INTRODUCTION: Early empirical broad-spectrum antimicrobial therapy is recommended for patients with severe infections, including sepsis. β-lactam/β-lactamase inhibitor combinations or carbapenems are often used to ensure coverage of likely pathogens. Piperacillin/tazobactam is proposed as a carbapenem-sparing agent to reduce the incidence of multidrug-resistant bacteria and superinfections. In the

The ac frequency in electrical power systems is conventionally regulated by synchronous machines. The gradual replacement of these machines by asynchronous renewable-based generation, which provides little or no frequency control, increases system uncertainty and the risk of instability. This imposes hard limits on the proportion of renewables that can be integrated into the system. In this paper,

Two-Higgs-doublet models (2HDMs) with a flavored U(1)′ gauge symmetry are a popular extension to the Standard Model (SM), yet they currently lack a complete survey. In this paper, we present a full classification of anomaly-free 2HDMs within the SM fermion content, resulting in a total of 11 distinct models. Four of these are relatively well studied, while the rest either partially, or entirely, l

As high technology device functionalities seem to constantly be moving towards decreasing critical dimensions and increasing density, there is a need for lithography research to move in the same direction. Block copolymer (BCP) lithography is a promising technique, which has single-digit nanometer resolution, typically has a pattern periodicity of 10-50 nm, and easily scales up the patterned area

There is a clinical need for improved wound treatments that prevent both infection and excessive inflammation. TCP-25, a thrombin-derived peptide, is antibacterial and scavenges pathogen-associated molecular patterns (PAMPs), such as lipopolysaccharide, thereby preventing CD14 interaction and Toll-like receptor dimerization, leading to reduced downstream immune activation. Here, we describe the de

Despite advances in the molecular exploration of paediatric cancers, approximately 50% of children with high-risk neuroblastoma lack effective treatment. To identify therapeutic options for this group of high-risk patients, we combine predictive data mining with experimental evaluation in patient-derived xenograft cells. Our proposed algorithm, TargetTranslator, integrates data from tumour biobank

Although automation has been introduced in all areas of public life, what seems to be missing is a reflection at the organizational or societal level about a policy of automation. By this we intend appropriate declarations made at the level of rationale, future plans and strategies to achieve intended goals and most importantly how those achievements will impact on various aspects of societal life

INTRODUCTION: Cerebral palsy (CP) is one of the most common neurodevelopmental disabilities. Yet, most individuals with CP are adults. How individuals with CP fare in terms of health, quality of life (QoL), education, employment and income is largely unknown. Further, little is known about the effects of having a child with CP on the parents. The Nordic countries are known for their strong welfare

Med hjälp av begreppet omsorgsrationalitet undersöker författaren några beskrivna församlingsdiakonala praktiker.

Even when the editor of the popular journal Populär Arkeologi claims to be communicating the latest advances in archaeological research to the public and that the authors often are professional archaeologists, this is done very rarely and focuses mostly on dating and artifacts. Is it the editor’s responsibility or must the archaeologists themselves highlight these issues in their articles? Common

Allt fler så kallade e-tjänster, exempelvis journaler på nätet, införs i vården. De kan dock leda till nya problem för personalen, inte minst när det gäller arbetsbelastning och yrkesroller. Projektet har tagit fram kunskap som förebygger arbetsmiljöproblem vid införandet av e-hälsotjänster.