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Two-colour time-resolved spectroscopy of helium using high-order harmonics

The radiative lifetime of the ls2p1P state of helium is measured in a two-colour ionization experiment with a 5% accuracy. The state is excited by the 13th harmonic of a tunable SO ps laser and ionized by a synchronous ultraviolet laser, with a variable time delay. This experiment demonstrates that the high harmonics generated in a jet of rare gas exposed to an intense laser field provide a tunabl

High-order harmonic generation in xenon : Intensity and propagation effects

We present experimental results on high-order harmonic generation in xenon, using a Nd:YAG laser (1064 nm). The harmonic generation efficiency is studied as a function of the laser intensity in the 1013 W/cm2 range. The harmonic conversion rates show a significant change of behavior when the medium becomes ionized (∼1013 W/cm2). This effect can be understood as the change of the nonlinear response

The origin of the occurrence rate profile of gas giants inside 100 d

We investigate the origin of the period distribution of giant planets. We fit the bias-corrected distribution of gas-giant planets inside 300 d found by Santerne et al. using a planet formation model based on pebble accretion. We investigate two possible initial conditions: a linear distribution of planetary seeds, and seeds injected exclusively on the water and CO icelines. Our simulations exclud

Focused laser intensity measurement at 1018 W/cm2 and 1053 nm

We present a simple experimental setup that makes possible the measurement of the beam section at focus under full-power conditions. We demonstrate that a 1.5-TW laser system can be focused down to a 13.5-μm-diameter spot using conventional lens focalization, thus achieving laser intensities of up to 1018 W/cm2.

Third-harmonic generation in xenon in a pulsed jet and a gas cell

We report experimental studies of harmonic generation in Xe using a 1064 nm Nd-YAG laser. Third-harmonic conversion is observed in a positively dispersive medium, using a tight-focusing geometry. The intensity of third-harmonic generation in a gas cell varies much more steeply with the laser intensity than a cubic law. The reason for the breaking of the phase matching condition is discussed.

Evidence for the formation of comet 67p/churyumov-gerasimenko through gravitational collapse of a bound clump of pebbles

The processes that led to the formation of the planetary bodies in the Solar system are still not fully understood. Using the results obtained with the comprehensive suite of instruments onboard the European Space Agency's Rosetta mission, we present evidence that comet 67P/Churyumov-Gerasimenko likely formed through the gentle gravitational collapse of a bound clump of mm-sized dust aggregates ('

Ac stark shifts induced by a YAG laser in the nP and nF Rydberg series in xenon

Nonresonant ac Stark shifts of Rydberg states in Xe have been investigated by probing an atomic transition with a weak UV light in the presence of an intense YAG-laser pulse. Rydberg atoms produced through two-photon excitation, 5p → np (n = 15-48) and 5p → nf (n = 12-49), are subsequently ionized. IR-laser-induced shifts of the resonant ionization profiles are then measured. The measured shift, 3

Spectroscopy of the np and nf even-parity rydberg series in xenon by two-photon excitation

The energies of the np[1/2]o, np[3/2]2, np[5/212, nf[3/2] 2, and nf[5/2]2 Rydberg states in Xe are measured within +0.3/-0.5 cm-1 from n = 12 to n = 49. The Rydberg states are excited by nonresonant two-photon absorption and detected by dc field ionization or infrared photoionization. We determine the ionization limit and the quantum defects for the different series involved.

Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci

Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, but the nature of the suggestive comorbidity is still unknown. We used a novel genetic pleiotropy-informed conditional False Discovery Rate (FDR) method to identify single nucl

Idrottande barn och ung­domar »vaccineras« mot frakturer i vuxenlivet : Träning är bra för alla – på olika sätt

High mechanical load in alternating directions with sufficient rest in between the loading periods is one of the best stimuli to enhance bone mass and skeletal structure, both contributing independently to bone strength. The age-frame where skeletal benefits from exercise are largest is in late pre- and early peri-puberty. Recent publications with low level of evidence infer that such skeletal ben

Abnormally decreased regional bone density in athletes with medial tibial stress syndrome

Medial tibial stress syndrome, a common condition of uncertain origin found in athletes, is characterized by pain in the distal posteromedial aspect of the tibia during exercise, with or without increased scintigraphic uptake in the affected region. To determine whether medial tibial stress syndrome with increased scintigraphic uptake is associated with a change in tibial bone mineral density conf

The duration of exercise as a regulator of bone mass

Exercise is associated with increased peak bone mineral density (BMD). To determine the relationship between the duration of exercise and BMD, we measured BMD of the axial and appendicular skeleton by dual-energy X-ray absorptiometry (DXA), and speed of sound (SOS), broadband attenuation (BUA), and stiffness index by quantitative ultrasound (QUS) of the calcaneus, in 67 active male national soccer

Bone loss in relation to menopause : A prospective study during 16 years

This prospective study evaluated bone loss in the peri- and postmenopausal period in 156 women followed from age 48 to 64 years. All women were premenopausal at the start of the study. Areal bone mineral density (g/cm2) was measured by single-photon absorptiometry (SPA) of the forearm at the 1 cm level (BMD 1 cm) and the 6 cm level (BMD 6 cm) every second year. Onset of menopause (MP) was determin

The evidence that exercise during growth or adulthood reduces the risk of fragility fractures is weak

There has never been, and will never be, a randomized double-blind placebo-controlled trial demonstrating that exercise in youth, adulthood or old age reduces fragility or osteoporosis-related fractures in old age. The next level of evidence, a randomized, controlled but unblinded study with fractures as an end-point is feasible but has never been done. The basis for the belief that exercise reduc

Skeletal effects of exercise in men

No prospective randomized study with fracture as end point exists in men. Data from retrospective and prospective observational and case control studies suggest that activity in men is associated with reduced fracture risk. This may be correct, but consistently replicated sampling bias may produce the same observation, as these studies are hypothesis generating, never hypothesis testing. Higher mu

Heterogeneity in the growth of the axial and appendicular skeleton in boys : Implications for the pathogenesis of bone fragility in men

Men with spine fractures have reduced vertebral body (VB) volume and volumetric bone mineral density (vBMD). Men with hip fractures have reduced femoral neck (FN) volume and vBMD, site-specific deficits that may have their origins in growth. To describe the tempo of growth in regional bone size, bone mineral content (BMC), and vBMD, we measured bone length, periosteal and endocortical diameters, B