To examine pathways of glutamate and glutamine metabolism in the ectomycorrhizal fungus Paxillus involutus, tracer kinetic experiments were performed using L-[U-C-14]glutamate and L-[U-C-14]glutamine and the enzyme inhibitors methionine sulfoximine (MSX), azaserine (AZA) and aminooxyacetate (AOA). When [C-14]glutamate was supplied to fungal cultures, 25% of the radioactivity of the amino acid frac

This paper empirically addresses two questions using a large, individual-level Swedish data set which links mortality data to health survey data. The first question is whether there is an effect of an individual's self-assessed health (SAH) on his subsequent survival probability and if this effect differs by socioeconomic factors. Our results indicate that the effect of SAH on mortality risk decli

Lifetimes of four short-lived levels belonging to the 4f(8)(F-7)6p configuration of Tb III have been measured using a two-step excitation time-resolved laser-induced fluorescence technique. They agree quite well with multiconfigurational relativistic Hartree-Fock calculations performed with inclusion of core-polarization effects. Using the experimental lifetimes and the theoretical branching fract

A previously developed biosensor for fast estimation of short-term biochemical oxygen demand (BODst) was used for off-line monitoring of intermediate products from the initial step of an anaerobic process in laboratory scale. Good agreement was generally achieved between the results from the biosensor method and the conventional 5-day test except for samples with high content of organic polymers.

Increased morbidity among teenage smokers has been reported, but specific current health problems and medication use other than of alcohol and narcotics have received less attention. The aim of this study was to examine the association between health problems and daily smoking in teenagers. Ninety percent of all teenagers attending junior high or high schools participated in a cross-sectional stud

Dinuclear carboxylate-bridged zinc complexes of one symmetric and one asymmetric phenolate-based ligand catalyse the transesterification of 2-hydroxypropyl-p-nitrophenyl phosphate (HPNP) at different rates, with an unsymmetrical complex being more active than a symmetric one.

New chemical probes were synthesized to label galectin-3. They are based on the high affinity thiodigalactoside ligand. The probes were synthesized with benzophenone or acetophenone moieties as the photolabel for covalent attachment to the protein. Besides labeling the protein, these aromatic photolabels also greatly enhance the affinity of the probes towards galectin-3, due to the interaction of

Background: Thrombomodulin (TM) is predominantly a vascular endothelial cell plasma membrane glycoprotein that, via distinct structural domains, interacts with multiple ligands, thereby modulating coagulation, fibrinolysis, complement activation, inflammation and cell proliferation. We previously reported that by mediating signals that interfere with mitogen-activated protein kinase and nuclear fa

Aberrations in the GI/S transition of the cell cycle have been observed in many malignancies and seem to be critical in the transformation process. Few studies have delineated the presence of GI/S regulatory defects and their clinical relevance in renal cell carcinoma (RCC). Therefore, we have examined the protein contents of cyclin D 1, D3, E, and p27 in 218 RCCs, using tissue microarray and immu

Both subjects with a low likelihood for coronary artery disease (CAD) and patients with normal findings on coronary angiography have been used as reference populations in non-invasive stress testing, including myocardial perfusion scintigraphy. Both of these criteria of normality--low likelihood of CAD and normal coronary angiography--have been criticised, and consensus on this issue is lacking. T

In this work H-1 NMR self-diffusion experiments have been performed to determine the self-diffusion coefficients of n-octyl beta-D-glucoside and n-nonyl beta-D-glucoside in alpha-cyclodextrin and beta-cyclodextrin solutions at 25 degreesC. Two questions are addressed. The first concerns the general influence on nonionic surfactant transport properties when cyclodextrins are present in solution. Th

The gamma decay of excited states in the N = Z odd-odd nucleus Rb-74 has been observed for the first time. The reaction Ca-40(Ca-40,alpha pn)Rb-74 at 128 MeV beam energy was used. The ground state rotational band can be interpreted as being formed from the T = 1 isobaric analog states of Kr-74 with pairing correlations based on T = 1, M(T) = 0 neutron-proton pairs. At higher rotational frequency,

Two ADP receptors have been identified on human platelets: P2Y(1) and P2Y(12). The P2Y(12) receptor blocker clopidogrel is widely used to reduce the risks in acute coronary syndromes, but, currently, there is no P2Y(1) blocker in clinical use. Evidence for variable responses to clopidogrel has been described in several reports. The mechanistic explanation for this phenomenon is not fully understoo

The Torrabaai-Koigabmond Complex (southern Kaoko Belt, Namibia) consists of three main intrusive rock types including metaluminous hornblende- and titanite-bearing quartz diorites, metaluminous hornblende- and biotite-bearing granodiorites and peraluminous garnet- and muscovite-bearing leucogranites. Uranium-Pb zircon data obtained on the granodiorites and leucogranites indicate concordia upper in

OBJECTIVE: The aim of this study was to investigate any association between vaginal carriage of Mycoplasma hominis and genital signs and symptoms, other microbial findings, and some risk behavior factors in women with and without bacterial vaginosis. STUDY DESIGN: Women who had attended two family planning clinics and a youth clinic for contraceptive advice were divided depending on the result of

The neotropical, freshwater copepod Notodiaptomus iheringi decreased the growth of small colonies in cyanobacteria-dominated plankton, indicating that they can be efficiently ingested and that they may represent an important food source for this copepod in reservoirs dominated by cyanobacteria. Cultured, colonial, toxic Microcystis aeruginosa was not affected, indicating that toxicity may cause a

Ocean waves exhibit more or less a Gaussian distribution for the instantaneous water surface height, and there is a need to develop simple models for generation of the characteristic non-Gaussian statistics, namely the asymmetric distributions of water surface height and wave slope. We argue that a simple class of non-linear oscillators can reproduce some of the characteristic features of random w

The recent interest in photodynamic therapy of human prostate cancer is accompanied by a need for techniques for in vivo monitoring of optical and physiological characteristics. We propose time-of-flight (TOF) spectroscopy in combination with Monte Carlo evaluation as a reliable optical technique for quantitative assessment of absorption, scattering, hemoglobin content and tissue oxygenation in th

Nanofiltration (NF) has attracted increasing attention during recent years due to the development of new applications. The advantage of NF compared with reverse osmosis (RO) and ultrafiltration (UF) is that it is possible to separate organic substances from some types of salts. It is, furthermore, also possible to separate different kinds of salts due to the negatively charged groups on the membra