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G protein-coupled estrogen receptor 1 (GPER) in the female reproductive tract: from physiology to cancer
Popular Abstract in Swedish Östrogen är ett av de viktigaste/ mest studerade kvinnliga könshormonerna som styr utvecklingen av våra fortplantningsorgan och deras reproduktionsförmåga. Östrogen påverkar dessutom många av kroppens andra organ, bland annat hjärnan, skelettet, och hjärt-kärlsystemet. Mängden östrogen som finns i kroppen varierar vanligtvis under menstruationscykeln och med kvinnans ålEstrogen effects are mediated either through genomic action involving the classical estrogen receptors, estrogen receptor alpha (ERα) and beta (ERß), which function as transcription factors in the nucleus, or through rapid non-genomic action via receptors associated with plasma membrane. Recently, a member of the G protein-coupled receptor family was ascribed estrogen receptor properties and propo
Hydrogen analysis and profiling with a position sensitive detector
The double sided silicon strip detector (DSSSD) is a segmented silicon detector commonly used in the fields of high energy physics and nuclear physics. This type of detector is used for analysis of reactions produced by charged particles. This makes it well suited for a number of analytical methods commonly used in ion beam analysis (IBA), such as Rutherford Backscattering (RBS) and elastic recoil
Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells
Popular Abstract in Swedish Allt liv på jorden är beroende av energi. Växter och vissa bakterier kan fånga och utnyttja solens energi för att bygga upp sina celler och dess delkomponenter som fetter, sockerarter och proteiner. Den energi som på så sätt blir bunden i dessa molekyler kan användas av djur och människor genom att vi konsumerar dem. För att energin skall kunna utnyttjas av kroppen måstSepsis is a devastating disease that is caused by the host’s response to an overwhelming infectious process. As sepsis progresses, organs distant from the site of infection become affected and sepsis-induced multiple organ failure ensues. An impaired immunologic response, including dysfunctional peripheral blood immune cells has been described as part of the septic syndrome. Mitochondrial dysfunct
Cell-line-specific stimulation of tumor cell aggressiveness by wound healing factors - a central role for STAT3
Background: Local recurrence is a major factor affecting survival after treatment for head and neck squamous cell carcinoma (HNSCC). It is possible that the normal processes involved in wound healing after surgical removal of a primary tumor can boost the regrowth of residual cancer cells, thereby contributing to the recurrent growth. In this work, we collected human wound fluids and used them to
Testing the quality of carriers: a field experiment on lizard signallers
In the Australian painted dragon lizard (Ctenophorus pictus), males occur in two different morphs with respect to gular color, with or without a yellow bib. Males without a bib lost within-clutch paternity significantly more often to rivals than bibbed males. Thus, it appears that bibs identify some phenotypic advantage linked to competitive ability. To test whether this could be related to whole-
Fragmentation and separation analysis of the photosynthetic membrane from spinach.
Membrane vesicles, originating from grana, grana core (appressed grana regions), grana margins and stroma lamellae/end membranes, were analysed by counter current distribution (CCD) using aqueous dextran-polyethylene glycol two-phase systems. Each vesicle population gave rise to distinct peaks in the CCD diagram representing different vesicle subpopulations. The grana vesicles and grana core vesic
Validity of diagnostic codes and prevalence of physician-diagnosed psoriasis and psoriatic arthritis in southern sweden - a population-based register study.
To validate diagnostic codes for psoriasis and psoriatic arthritis (PsA) and estimate physician-diagnosed prevalence of psoriasis and PsA in the Skåne region, Sweden.
Use of financial bootstrapping in new businesses: a question of last resort?
This study examines motives for using financial bootstrapping in new businesses. First, it identifies and labels groups of new business founders based on their motives for using bootstrapping. Second, it examines the relation between variables referring to the founder and the business and the motives. The data were collected in a questionnaire sent by post to 120 new business founders in Swedish b
Psychometric properties of the disease-specific health-related quality of life instrument VascuQoL in a Swedish setting
Background: Traditional outcome measures in peripheral arterial disease (PAD) provide insufficient information regarding patient benefit. It has therefore been suggested to add patient-reported outcome measures. The main aim of this study was to validate the Swedish Vascular Quality of Life questionnaire (VascuQoL) version, a patient-reported PAD-specific health-related quality of life (HRQoL) ins
Search for new phenomena with the monojet and missing transverse momentum signature using the ATLAS detector in root s=7 TeV proton-proton collisions
A search for new phenomena in events featuring a high energy jet and large missing transverse momentum in proton-proton collisions at root s = 7 TeV is presented using a dataset corresponding to an integrated luminosity of 33 pb(-1) recorded with the ATLAS detector at the Large Hadron Collider. The number of observed events is consistent with the Standard Model prediction. This result is interpret
A European survey of atmospheric heavy metal deposition in 2000-2001
The background, administration and current status of the monitoring programme "European Survey of Atmospheric Heavy Metal Deposition" is described. All European states are invited to join the survey 2000-2001. The co-ordination and responsibility for the survey will gradually be transferred from the Nordic Council of Ministers to the International Cooperative Programme on Effects of Air Pollution
Hypotermi efter perinatal asfyxi minskar risken för hjärnskada. Men för tidigt att rekommendera rutinmässig behandling
Måttlig hypotermi efter perinatal asfyxi reducerar mortaliteten och risken för överlevnad med svårt handikapp, visar två randomiserade, kontrollerade studier. Fler studier pågår och förväntas bli publicerade inom de närmaste åren. Den publicerade studien visar dock att det endast är barn med måttlig hjärnskada som har effekt av hypotermi. Hypotermi efter perinatal asfyxi kan ännu inte rekommenderaTwo randomised controlled trials evaluating intervention with moderate hypothermia after perinatal asphyxia will probably be published this year. The first study, evaluating head cooling with a "cool cap" is already published, and preliminary data from the other study evaluating body cooling earlier have been presented. Both studies indicate that moderate hypothermia, initiated within 6 h after bi
Perforations of the Upper Gastro-Intestinal Tract
Material and methods: In all, 237 consecutive patients with a perforated peptic ulcer admitted from 1974-1992 and 125 consecutive patients with an oesophageal perforation admitted from 1970-2006 to Lund University hospital were studied retrospectively. Prognostic factors were evaluated using the Cox proportional hazards model. All cases of gastro-duodenal ulcer perforations diagnosed in Sweden fr
Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: Results of the CABG surgery cohort of the GUARDIAN study
Objectives: To evaluate the effects of cariporide on all-cause mortality or myocardial infarction at 36 days in patients at risk,of myocardial necrosis after coronary artery bypass graft surgery. Methods: In the coronary artery bypass graft cohort of the GUARD During Ischemia Against Necrosis trial, patients greater than or equal to 18 years who required urgent coronary artery bypass graft, repeat
The fate of assimilated carbon during drought: impacts on respiration in Amazon rainforests
Interannual variations in CO2 exchange across Amazonia, as deduced from atmospheric inversions, correlate with El Nino occurrence. They are thought to result from changes in net ecosystem exchange and fire incidence that are both related to drought intensity. Alterations to net ecosystem production (NEP) are caused by changes in gross primary production (GPP) and ecosystem respiration (R-eco). Her
Prognostic effects of pre-hospital and in-hospital therapeutic interventions on 30-days mortality in patients with cardiogenic shock
Activation of a Temporal Memory in Purkinje Cells by the mGluR7 Receptor.
Cerebellar Purkinje cells can learn to respond to a conditioned stimulus with an adaptively timed pause in firing. This response was usually ascribed to long-term depression of parallel fiber to Purkinje cell synapses but has recently been shown to be due to a previously unknown form of learning involving an intrinsic cellular timing mechanism. Here, we investigate how these responses are elicited
Skräddaren, sömmerskan och modet : arbetsmetoder och arbetsdelning i tillverkningen av kvinnlig dräkt 1770-1830
The aim of this study in textile studies and cultural history is to gain a greater understanding of what happened to the division of labour and manufacturing techniques when female fashions changed in the period 1770-1830. This was a time of upheaval as regards fashions, and a change in dress practice. The decades around 1800 were a period of major societal and cultural transformation. Female fash
Lavar på Jordö
Denna rapport baseras på två inventeringar. Dels en inventering av sten- och jordlavar som genomfördes den 25 juli 2009 av Lars Fröberg, dels en inventeringen av skyddsvärda träd som genomfördes mellan 21 oktober och 12 november 2008 av Mattias Lif och Sofie Willman. Jordö är en halvö vid västra delen av Almö som ligger i norra delen av Listerby skärgård. Området är troligtvis ett av de artrikaste