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Neuronal signal substances as biomarkers of migraine

Of the sensory nervous system associated signal substances it is only calcitonin generelated peptide (CGRP) that is reliably associated with the degree of pain in the acute attacks of primary headaches. The treatment with triptans alleviates both the pain and the associated CGRP release, putatively via a presynaptic effect on the sensory nerves. The studies of opoids and other sensory neuropeptide

Benchmark Simulation Model No 2 in Matlab-Simulink: towards plant-wide WWTP control strategy evaluation

In this paper, implementation of the Benchmark Simulation Model No 2 (BSM2) within Matlab-Simulink is presented. The BSM2 is developed for plant-wide WWTP control strategy evaluation on a long-term basis. It consists of a pre-treatment process, an activated sludge process and sludge treatment processes. Extended evaluation criteria are proposed for plant-wide control strategy assessment. Default o

Proteomics principles and challenges

Proteomics studies rely on high-resolving separation techniques whereby the biological complexity can be unraveled. Both gel-based and liquid-phase separation principles are needed in order to mine deeper into the low abundant area of the proteins expressed in human cell samples. The expression levels that can be reached today with proteomics technology are still only reaching part of all proteins

Custom Datapaths for DSP ASICs Methodology and Implementation

This thesis regards datapath design and analysis at several abstraction levels. Five papers are presented that focus on datapath design for mobile communication systems and design methodologies for such datapaths. Paper I discusses different aspects of Turbo channel decoder design for high speed and low power applications. It is shown that critical path delay is significantly reduced by simple re

In the shadow of bad news - views of patients with acute leukaemia, myeloma or lung cancer about information, from diagnosis to cure or death

Many studies have been published about giving and receiving bad messages. However, only a few of them have followed the patients all the way through a disease as is done in this study. Many studies have been written about patients' coping strategies. In this study we will keep within the bounds of coping through information only. The aim of the study is to investigate patients' views of informatio

Sales of tranquillizers, hypnotics/sedatives and antidepressants and their relationship with underprivileged area score and mortality and suicide rates

OBJECTIVE: This study analyses the correlation between the Swedish underprivileged area score and sales of tranquillizers, hypnotics/sedatives, neuroleptics and antidepressants, and the correlation between these sales and mortality and suicide rates, with the aim of using sales data to identify areas with poor socioeconomic conditions. SETTING: Southern Sweden, 33 municipalities in Skane, 1987 and

Modeling nutrient cycling and sustainable forest growth in a changing world

Popular AbstractSveriges relativa välstånd kan vi till stor del tacka skogen för. Skogen har ända sedan industrialiseringen började ta fart i Sverige bidragit med betydande exportinkomster. För att bevara den inkomstkälla skogen utgör måste vi se till att det skogsbruk som bedrivs är uthålligt och tar hänsyn till såväl ekonomiska som biologiska och sociala aspekter. Skogsproduktionen ska med andraIt took 70-80 years to realize the width of the impact of industrialization on the forest ecosystems since a forest ecosystem is a "slow system" as seen from a human perspective. An anticipated future climate change and increasing carbon dioxide and ozone levels will change the conditions even more with time and the widely used statistical forest growth models will not be applicable anymore. Compu

Electronic speckle pattern interferometry: A tool for determining diffusion and partition coefficients for proteins in gels

The aim of this study was to demonstrate electronic speckle pattern interferometry (ESPI) as a powerful tool in determining diffusion coefficients and partition coefficients for proteins in gels. ESPI employs a CCD camera instead of a holographic plate as in conventional holographic interferometry. This gives the advantage of being able to choose the reference state freely. If a hologram at the,re

Viljen vi veta, viljen vi förstå ... : kunskapsbildning inom socialtjänsten

Denna rapport handlar om socialtjänstens kunskapsbildning. I dess inledning konstateras att kunskapsutveckling är något som ligger i tiden. Från flera håll pekas det på att det sker stora och viktiga insatser på detta område medan socialtjänsten av någon anledning tycks ha hamnat i skamvrån. I själva verket riktas det från flera oberoende håll stark kritik mot dess verksamhet och det hävdas att ar

Neuropeptide Y-2 receptors are involved in enhanced neurogenic vasoconstriction in spontaneously hypertensive rats

1 The present study addressed the role of neuropeptide (NPY) Y-2 receptors in neurogenic contraction of mesenteric resistance arteries from female spontaneously hypertensive rats (SHR). Arteries were suspended in microvascular myographs, electrical field stimulation (EFS) was performed, and protein evaluated by Western blotting and immunohistochemistry. 2 In vasopressin-activated endothelium-intac

Acute effects of D-1 and D-2-receptor agonist and antagonist drugs on somatostatin binding, inhibition of adenylyl cyclase activity and accumulation of inositol 1,4,5-trisphosphate in the rat striatum

A recent study carried out by our group demonstrated that exogenous dopamine increases the somatostatin (SS) receptor–effector system in the rat striatum. The present study examined the participation of the D1- and D2-dopaminergic systems in the modulation of the rat striatal SS receptor–effector system by use of the D1-receptor agonist and antagonist SKF 38393 and SCH 23390, respectively, and the

Solar Wind Variations Related to Fluctuations of the North Atlantic Oscillation

A study on a possible solar wind interaction with the North AtlanticOscillation (NAO) is performed. Results are presented suggesting arelationship between the NAO index and the electric field strength E ofthe solar wind. A possible scenario for the suggested interaction isthat an electromagnetic disturbance is generated by the solar wind inthe global electric circuit of the ionosphere. This distur

Intravesical adenosine triphosphate stimulates the micturition reflex in awake, freely moving rats.

PURPOSE: Adenosine triphosphate (ATP) (Sigma Chemical Co., St. Louis, Missouri) is known to contract animal as well as human detrusor muscle and recent investigations have shown an involvement of ligand gated purinergic-1 receptors in detrusor contraction. In addition, ligand gated purinergic-3 receptors have been demonstrated on suburothelial sensory nerves (C-fibers) and may be involved in diste

Strategies for Industrial Relevance in Software Engineering Education

This paper presents a collection of experiences related to success factors in graduate and postgraduate education. The experiences are mainly concerned with how to make the education relevant from an industrial viewpoint. This is emphasized as a key issue in software engineering education and research, as the main objective is to give the students a good basis for large-scale software development

His Bobness

En recension av Mats Jacobssons doktorsavhandling om bob Dylans texter.

Generation of clusters of free eosinophil granules (Cfegs) in seasonal allergic rhinitis

Generation of clusters of free eosinophil granules (Cfegs), through lysis of eosinophils, has recently been proposed as a major paradigm for ultimate activation of airway mucosal eosinophils. In the present study involving patients with seasonal allergic rhinitis, we have investigated whether generation of Cfegs in the nasal mucosa is a feature of allergic rhinitis. Nasal mucosal biopsies were obt

The effect of pasture on starling (Sturnus vulgaris) breeding success and population density in a heterogenous agricultrual landscape in Southern Sweden

Populations of European starlings have declined over large parts of northern and western Europe during the last 20 years. It has been suggested that reduced availability of pasture in the agricultural landscape was one reason for this decline. To investigate this, breeding colonies for starlings were established in southern Sweden, in agricultural landscapes with different availabilities of pastur

Invändig tilläggsisolering : köldbryggor, fukt, rörelser och beständighet : thermal bridges, moisture problems, movements and durability = Internal additional insulation

The report deals with the problems which may be caused by internal additional insulation of an existing building component. Problems treated in this report are heat losses through and surface condensation at thermal bridges, condensation in the building components, stresses due to temperature and moisture content variations and possibly frost damage in facade materials. After internal insulation