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Intracapsular pressure and pain in coxarthrosis

Intracapsular hip pressure was measured before surgery in 17 patients (18 hips) with coxarthrosis. The results were correlated to pain as registered on a visual analog scale. With the hip in extension, the pressure was 49.5 mmHg (SD, 40.2); in 45 degrees of flexion, it was 21.3 mmHg (SD, 14.6); in extension and inward rotation, it was 105.7 mmHg (SD, 76.0); and in extension and outward rotation, i

Follow-up of antiretroviral treatment in liver transplant recipients with primary and chronic HIV type 1 infection

The prognosis of HIV-1-infected patients has dramatically improved but progression to liver failure occurs now frequently in subjects coinfected with hepatitis C virus (HCV). This has raised the issue of organ transplantation, but the knowledge about the effect of concomitant antiretroviral and immunosuppressive therapy is limited. The objective of the study was to describe viral and immunological

Directed self-organization of single DNA molecules in a nanoslit via embedded nanopit arrays

We show that arrays of nanopit structures etched in a nanoslit can control the positioning and conformation of single DNA molecules in nanofluidic devices. By adjusting the spacing, organization and placement of the nanopits it is possible to immobilize DNA at predetermined regions of a device without additional chemical modification and achieve a high degree of control over local DNA conformation

Block-copolymer micro-emulsion with solvent-induced segregation

Reverse micelle formation of the poly(ethylene oxide)/poly(propylene oxide) block-copolymer (EO)(13)(PO)(30)(EO)(13) (L64) in p-xylene was investigated as a function of water content and copolymer content, using small-angle neutron scattering (SANS). PEO/PPO block-copolymers are generally soluble in xylene but without forming aggregates. However, the effective block segregation increases dramatica

CoGenT++: an extensive and extensible data environment for computational genomics

Motivation: CoGenT++ is a data environment for computational research in comparative and functional genomics, designed to address issues of consistency, reproducibility, scalability and accessibility. Description: CoGenT++ facilitates the re-distribution of all fully sequenced and published genomes, storing information about species, gene names and protein sequences. We describe our scalable imp

Weak- and strong-coupling electrostatic interactions between asymmetrically charged planar surfaces

We compare weak- and strong-coupling theory of counterion-mediated electrostatic interactions between two asymmetrically charged plates with extensive Monte Carlo simulations. Analytical results in both weak- and strong-coupling limits compare excellently with simulations in their respective regimes of validity. The system shows a surprisingly rich structure in terms of interactions between the su

An experimental manometric study simulating upper esophageal sphincter narrowing

RATIONALE AND OBJECTIVES. Elevated intrabolus pressure above a pharyngeal narrowing has been postulated as an important finding in patients with cricopharyngeal bars. To elucidate the significance of intrabolus pressure around lumen narrowings in the pharynx, intraluminal pressure characteristics were evaluated in a laboratory model simulating upper esophageal sphincter narrowing. METHODS. Intralu

Documentation of soiled and biodeteriorated facades: a case study on the Coliseum, Rome, using hyperspectral imaging fluorescence lidars

Non-invasive documentation of historic façades with fluorescence lidar techniques can provide helpful information for the cultural heritage sector, especially when large areas outdoors are to be examined. This paper presents a case study on the Coliseum, Rome, where both cleaned and heavily soiled areas of the monument were scanned and analysed with two fluorescence lidar systems. Biodeterioration

A plasma membrane zinc transporter from Medicago truncatula is up-regulated in roots by Zn fertilization, yet down-regulated by arbuscular mycorrhizal colonization

Here we present a Zn transporter cDNA named MtZIP2 from the model legume Medicago truncatula. MtZIP2 encodes a putative 37 kDa protein with 8-membrane spanning domains and has moderate amino acid identity with the Arabidopsis thaliana Zn transporter AtZIP2p. MtZIP2 complemented a Zn-uptake mutant of yeast implying that the protein encoded by this gene can transport Zn across the yeast's plasma mem

Computer-assisted calculation of myocardial infarct size shortens the evaluation time of contrast-enhanced cardiac MRI

Background: Delayed enhancement magnetic resonance imaging depicts scar in the left ventricle which can be quantitatively measured. Manual segmentation and scar determination is time consuming. The purpose of this study was to evaluate a software for infarct quantification, to compare with manual scar determination, and to measure the time saved. Methods: Delayed enhancement magnetic resonance ima

Biotite and muscovite 40Ar/39Ar geochronological constraints on the post-Svecofennian tectonothermal evolution, Forsmark site, central Sweden

In order to characterize the post-Svecofennian tectonothermal evolution of the Fennoscandian Shield, 40Ar-39Ar biotite and some 40Ar-39Ar muscovite geochronological data are reported from a total of 30 surface outcrop and 1000 m long borehole samples at Forsmark, central Sweden. The thirteen surface samples were collected across three branches of a major WNW to NW trending system of deformation zo

Genetic aberrations in hypodiploid breast cancer: frequent loss of chromosome 4 and amplification of cyclin D1 oncogene

The evolution of somatic genetic aberrations in breast cancer has remained poorly understood. The most common chromosomal abnormality is hyperdiploidy, which is thought to arise via a transient hypodiploid state. However, hypodiploidy persists in 1 to 2% of breast tumors, which are characterized by a poor prognosis. We studied the genetic aberrations in 15 flow cytometrically hypodiploid breast ca

Relationship between the electrical and rheological properties of potato tuber tissue after various forms of processing

The impedance at frequencies of 1-1000 kHz and dynamic bending storage modulus measured by the vibrating reed method were compared for potato tuber tissue, which had been processed by various methods. Raw potato tuber tissue strips were either heated for 30 min up to 100°C or frozen-thawed. Some samples were osmotically dehydrated in a mannitol solution up to a concentration of 0.7 mol/l. The elec

Social capital, the miniaturization of community and high alcohol consumption: a population-based study

Aims: To study the impact of social participation, trust, and the miniaturization of community, i.e. high social participation/low trust, on the risk of high alcohol consumption. Methods: The Scania 2000 public health survey is a cross-sectional, postal questionnaire study. A total of 13 604 persons aged 18–80 years were included. A logistic regression model was used to investigate the association